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Life Threatening? No
Write-up: RUPTURED ACUTE MYOCARDIAL INFARCTION OF THE ANTERIOR ASPECT OF THE LEFT VENTRICLE; unresponsive; FEELING UNWELL; This is a spontaneous report from a contactable other healthcare professional (Coroner) downloaded from the a regulatory authority. The regulatory authority report number is [IE-HPRA-2021-074281]. A 57-years-old male patient received bnt162b2 (COMIRNATY), dose 1 via an unspecified route of administration on 13May2021 (Lot Number: Unknown) as single dose for covid-19 immunization at the age of 57 years old. Medical history included Chronic ischaemic heart disease, unspecified and aortic valve replacement. Concomitant medication(s) included warfarin. The patient experienced feeling unwell on 13May2021, ruptured acute myocardial infarction of the anterior aspect of the left ventricle on 16May2021. Reported as: On 13May2021, following vaccination, the patient felt unwell that night, next day and again on 16May2021. On 16May2021, the patient was found unresponsive on the floor at home. Given the temporal relationship between the first vaccine and death, a Coroner''s autopsy was directed. On 19May2021, the post-mortem report indicated that the cause of death was a ruptured acute myocardial infarction of the anterior aspect of the left ventricle in the context of chronic ischaemic heart disease and aortic valve replacement. It was noted that nasopharyngeal swab was obtained, which SARS-CoV-2 RNA was not detected on 19May2021. The patient died on 16May2021. An autopsy was performed that revealed ruptured acute myocardial infarction of the anterior aspect of the left ventricle. No follow-up attempts are possible; information about lot/batch number cannot be obtained.; Reported Cause(s) of Death: unresponsive; RUPTURED ACUTE MYOCARDIAL INFARCTION OF THE ANTERIOR ASPECT OF THE LEFT VENTRICLE; FEELING UNWELL; Autopsy-determined Cause(s) of Death: RUPTURED ACUTE MYOCARDIAL INFARCTION OF THE ANTERIOR ASPECT OF THE LEFT VENTRICLE
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