National Vaccine
Information Center

Your Health. Your Family. Your Choice.

MedAlerts Home
Search Results

Found 472 cases where Vaccine targets Measles (MEA or MER or MM or MMR or MMRV) and Patient Died and Vaccination Date on/before '2018-11-30'

Case Details

This is page 33 out of 48

Result pages: prev   24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42   next


VAERS ID: 188088 (history)  
Form: Version 1.0  
Age: 9.0  
Sex: Female  
Location: Foreign  
Vaccinated:1982-01-01
Onset:1982-04-01
   Days after vaccination:90
Submitted: 2002-07-23
   Days after onset:7417
Entered: 2002-07-29
   Days after submission:6
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MEA: MEASLES (ATTENUVAX) / MERCK & CO. INC. - / UNK - / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: Brain oedema, Cardio-respiratory arrest, Cerebellar syndrome, Choking, Coma, Difficulty in walking, Disturbance in attention, Drooling, Dyskinesia, Electroencephalogram abnormal, Encephalitis, Hypotonia, Infection, Irritability, Lethargy, Mood swings, Pneumonia, Posturing, Visual disturbance
SMQs:, Torsade de pointes/QT prolongation (broad), Anaphylactic reaction (narrow), Angioedema (broad), Peripheral neuropathy (broad), Hyperglycaemia/new onset diabetes mellitus (broad), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Arrhythmia related investigations, signs and symptoms (broad), Shock-associated circulatory or cardiac conditions (excl torsade de pointes) (narrow), Dementia (broad), Dyskinesia (narrow), Dystonia (broad), Parkinson-like events (broad), Acute central respiratory depression (broad), Psychosis and psychotic disorders (narrow), Guillain-Barre syndrome (broad), Noninfectious encephalitis (narrow), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Hyponatraemia/SIADH (broad), Hostility/aggression (broad), Haemodynamic oedema, effusions and fluid overload (narrow), Glaucoma (broad), Optic nerve disorders (broad), Lens disorders (broad), Eosinophilic pneumonia (broad), Retinal disorders (broad), Depression (excl suicide and self injury) (broad), Hypotonic-hyporesponsive episode (broad), Generalised convulsive seizures following immunisation (broad), Hypersensitivity (broad), Respiratory failure (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Hypoglycaemia (broad), Infective pneumonia (narrow)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: ABO incompatibility; chickenpox; croup; jaundice NOS; measles; pneumonia NOS
Allergies:
Diagnostic Lab Data: 4/19/90; EEG-bilateral slow delta waves over the posterior temporal regions; Physical exam-blunt affect, slow responses, well oriented, head and neck including cranial nerves were nml; normal muscle mass, tone and reflexes bilaterally, difficulty walking in a straight line, mild dysdiadochokinesis and impaired finger-nose touching; Renal function study-nml; urinalysis-neg for lead and mercury; CSF-nml; serum electrolytes-nml; thyroid function-nml; CBC-nml; 4/23/90 measles antibody titers on-1:128,000 serum; Elisa-1:6400 CSF; both plantars upgoing; myoclonic jerks; reflexes including jaw jerk were brisk, deficits in gait and other motor skills worsened; complement fixation test-1:4 CSF; complement fixation test-1:1024 serum; EEG-periodic discharge activity synchronous with myoclonic jerks; serum and CSF displayed prominent antibody reactivity; measles IgM was present in CSF; 5/19/90 decorticate posturing; Autopsy 5/90 ?-brain was diffusely edematous, flattened gyri, narrowed sulci, slit-like ventricles; brain weight 14 days formalin fixation 1410 grams; multiple foci of cortical necrosis; numerous intranuclear and cytoplasmic eosinophilic viral inclusion bodies were observed; lungs showed severe bronchopneumonia; spinal chord not examined; electron microscopy confirmed presence of numerous tubular nucleocapsids
CDC Split Type: WAES0207CAN00051

Write-up: Information has been received from authors of a literature article concerning a 9 year old female with a history of jaundice due to ABO incompatibility in the neonatal period, chickenpox at 2 years of age, croup at the age of 2 and a half, and pneumonia NOS at 7 and a half years of age who in 1/82, was vaccinated with MMR. In 4/82, the pt experienced an attack of presumed measles. The authors reported that the pt had progressed in her development well and was doing well in school, the pt was 1 of 3 siblings, in which 1 of her siblings had mild visual perception difficulties. One of the pt''s maternal aunts on her father''s side was thought to suffer from a demyelinating neurotic disease. A maternal cousin had multiple sclerosis and it was also reported that there was no history of consanguinity. On approx. 4/10/90, the pt experienced deterioration in hand writing and difficulty in walking and in concentrating. The authors also reported that the pt was moody and irritable with marked deterioration of vision and increasing lethargy. On 4/17/90, the pt started drooling and had 2 episodes of choking. Ten days earlier, she had been able to do gymnastics. On 4/19/90, the pt experienced delayed acute measles inclusion body encephalitis and was hospitalized. The authors reported that upon physical exam, the pt had a blunt affect, slow responses and well oriented. The head and neck including cranial nerves were normal. The pt''s muscle mass and tone were normal and had normal bilateral reflexes, both plantar reflexes were down going. The pt''s sensory system was reported as normal. The pt had difficulty in walking in a straight line, mild dysdiadochokinesis, and had impaired finger-nose touching. On 4/23/90, the pt was referred to a Hospital for further investigation, at which point, all the pt''s reflexes were brisk including her jaw jerk, both plantars were up going and the pt''s deficits in gait and other motor skills steadily worsened. The pt started having myoclonic jerks and a repeat EEG showed periodic discharge activity synchronous with myoclonic jerks. The pt underwent further test. The authors reported that the pt was thought to have subacute sclerosing panencephalitis. On 5/19/90, the pt''s lever of consciousness deteriorated and started having decorticate posturing. Her condition deteriorated rapidly, she became comatose and developed multiple episodes of aspiration pneumonia. Subsequently, she had a cardiorespiratory arrest. She died 6 weeks after the onset of symptoms. A diagnostic pathological exam that was performed 2 hours after death, showed that the brain was diffusely edematous, flattened gyri, narrowed sulci, slit-like ventricles and weighed 1410 grams after 14 days formalin fixation. The authors also reported that there were multiple foci of cortical necrosis, numerous intranuclear (Cowdry type A) and cytoplasmic eosiniphillic viral inclusion bodies that were observed in neurons and glial cells were present in the brain as well as in the leptomenginges. No neurofibrillary tangles of Alzheimer type or demyelination were observed and gliosis was not prominent. A marked contrast of the measles viral antigen distribution between the gray matter and white matter of the cerebral hemispheres was revealed in the immunohistologic exam. The white matter of the cerebral hemispheres was heavily loaded with the viral antigen, which was easily noticeable with unaided eye. However, the upper portion of the cortex was virtually free of the viral antigen. In between them, some neurons in the deeper portion of the cortex displayed a linear distribution of the viral antigen in the cytoplasmic extensions as well as in the cell bodies. The viral antigen was seen in the dendrites with acute angle branches and also in the straight axons with rare right angle branches. There was also M protein present in the cytoplasm of the cells. In situ hybridiration with digoxigenin labeled probes for NP gene revealed the presence of numerous tubular nucleocapsids (of 20nm in diameter) in the cytoplasm as well as in he nucleus of neurons and the glial cells. There was also the presence of clusters of tubular nucleocapsids in the dendrites and axons. A severe bronchopneumonia was revealed in the lungs. No viral inclusions or antigen could be demonstrated in any other organ than the brain. The authors concluded by saying that the cause of death was "delayed type of acute measles inclusion body encephalitis and severe bronchopneumonia". The authors reported that the pt followed, for only 6 weeks after onset, a rapidly progressive downhill course. The latent period was aprox. 7 years following vaccination and measles infection. This case is reported as being consistent with delayed acute type of measles inclusion body encephalitis without immunosuppression. The observed features in this case probably reflect the short duration of illness. The heavy involvement of the white matter by the viral antigen is consistent with the clinical history of predominant motor dysfunction and relative preservation of intelligence in the beginning as well as the absence of seizure activity. No further information is available.


VAERS ID: 192483 (history)  
Form: Version 1.0  
Age: 1.0  
Sex: Male  
Location: Foreign  
Vaccinated:1994-10-13
Onset:0000-00-00
Submitted: 2002-10-30
Entered: 2002-11-05
   Days after submission:6
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 1037W / UNK - / -

Administered by: Unknown       Purchased by: Unknown
Symptoms: Autism, Gastrointestinal disorder, Hydroureter, Psychomotor hyperactivity
SMQs:, Anticholinergic syndrome (broad), Retroperitoneal fibrosis (narrow), Dementia (broad), Akathisia (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Hostility/aggression (broad), Depression (excl suicide and self injury) (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: UNK
CDC Split Type: WAES0210USA02146

Write-up: Information has been received regarding a case in litigation concerning a male child who on 10/13/94, at the age of 12 months was vaccinated with a dose of MMR II (lot 609861/1037W; batch 850672). It is alleged that following the vaccination the pt developed Asperger''s syndrome and bowel problems. Upon internal review the pt''s Asperger''s syndrome and bowel problems were considered to be other important medical events (OMIC). No further info is available. A 15-day follow up report received 3/10/2003 adds: Information has been received concerning a 13 month old male child with mild asthma, mild hydroureteronephrosis and a medical history of clicking hips, bilateral ureteric reflux, and meconium staining of the liquor during during, who on 10/13/1994 was vaccinated with a dose of measles virus vaccine live (+) mumps virus vaccine live (+) rubella virus vaccine live (second generation) (Lot #609861/1037W: Batch #950672 (diluent)). It is alleged that following the vaccination the pt developed Asperger''s syndrome, Attention Deficit Disorder with Hyperactivity, and Lymphoid Nodular Hyperplasia in the terminal ileum. Additional info was received and indicted that the pt was crying, screaming and writhing about on one afternoon during the week post vaccination. This was unusual, as the pt never behaved like this before. Within 6 weeks post vaccination, the pt began to pick up his toys one after the other, look at them and then throw them away. He was no longer playing appropriately with them. Also the pt was extremely restless. He was not seeking out the company of adults as he had done before. He started to throw heavy objects around the house. Also within 8 weeks, his speech patterns had changed and from conversational cadences to being less talkative and expressing himself in a kind of gibberish that did not sound like conversational attempts. Within 3 to 4 months, his sleep patterns completely changed. He now needed little sleep, during which he was restless and twitchy. Within approximately 6 months, the pt had developed an obsession with the same audio and videocassettes. He would play then 30 or 40 times over and over again. If they were turned off, he would scream for hours. Within 6 months, the pt was displaying many typical autistic traits. He had gradually begun hand wringing and having temper tantrums. He had also lost all of his eye contact gradually in the 6 months post vaccination. He did not want to be near familiar people and developed a severe dislike of strangers. He would arch his body and go completely rigid if he was somewhere that he was uncomfortable with. In February 1997, the pt was seen by a pediatrician and was diagnosed as having attention deficit disorder with hyperactivity. He was prescribed methylphenidate (RITALIN) which made his condition worse and so he was brought off it after 3 months. On 05/07/1998, the pt was diagnosed with Asperger''s syndrome. Following continuous bouts of constipation for a period of around 12 months, the pt was seen and referred by a general practitioner on 06/16/1999. The pt underwent a colonoscopy on 05/16/2000 and the specialist in pediatric gastroenterology made a diagnosis of Grade 2 lymphoid nodlar hyperplasia in his terminal ileum with loss of vascular pattern up to the transverse colon. During the same appointment, the pt underwent an OGD (oesophagogastroduodenoscopy) that showed normal oesophagus, minimal antral erythema and duodenal erythema in ''D1''. In an assessment performed on 05/01/1997, at the age of 3.5 years old, a physician indicated that the pt''s mother had non-insulin dependent diabetes and needed insulin during pregnancy. The pt was born vaginally at 40 weeks without problems after an induction. He was an easy baby, slept a lot and was breast-fed until 8 months. He began verbalizing at about a year old and had a few words by the age 0f 2. He was talking in sentences now. His parents could not remember when the pt began to sit, crawl, stand, or walk but felt that they were within normal limits. He was an affectionate child. The pt was currently on methylphenidate (RITALIN) 5mg ''mane''. None at weekends. His parents indicated that his behavior was very destructive and had general motor over-activity. He would go around touching everything. He would interrupt others constantly and found it difficult to listen. They reported that he was generally quite easily distractible but with certain tasks, such as sitting with a book, using the computer or watching videos, he was able to maintain concentration. Mealtimes were also difficult in getting him to sit down and eat. His mother felt that the pt was more amenable since starting methylphenidate (RITALIN) with less tantrums and was more settled. His father felt that it made little difference. The pt appeared to have quite a number of ritualistic, almost obsessional behaviors. For istance, the pt insisted that he must eat this breakfast while wearing his dressing gown. He insisted that many tasks are done in a specific order and also had his own ''special tasks'' such as putting lids on bottles or putting fruit into plastic bags in the supermarket. He also appeared to have a compulsive need to touch things. He had a particular interest in books of any kind and will sit and ''read'' a book from cover to cover. He would throw a tantrum, lasting for an hour or so, if he were not allowed to finish the task. Recently, the pt had been experiencing night terrors. Toileting is another main problem. Toilet training had begun last summer and he was dry during the day to the point where he was able to wear ordinary pants but was still soiling. He appeared to be retaining his feces but constipation was ruled out as a possible cause and laxatives were of little help as he was producing small amounts often. Currently, he refused to use a pot; he said, ''I can''t''. He was back to wearing nappies full time now. He played quietly and appropriately with toys on his own for most of the interview. He seemed placid and happy. Although the pt did seem to have some of the features of ADHD (attention-deficit hyperactivity disorder), in general his behavior did not seem to have the pervasiveness that one would expect with such a diagnosis. Medication appeared to have helped with some of his behavior, but then it can also bring about improvements in concentration and ability to settle to tasks in children without such a diagnosis. Regarding his problems of soiling, if constipation has been ruled out as a cause, then it might be a behavioral expression over issue of control. A behavioral approach was suggested for toileting problems. In an assessment performed on 08/13/1997, a physician indicated that the pt was born at 40 weeks following induction. There was meconium staining of the liquor. Chicking hips were diagnosed at birth that resolved spontaneously. Bilateral ureteric reflux was also diagnosed early. Motor milestones were achieved without difficulty and the pt was walking by his first birthday. Theh 18-month check highlighted concerns about the pt''s hearing because of his speech was not making expected progress. He was starting to talk at about 2 years old. His vocabulary grew satisfactorily and sentences developed at the expected time. It was the content of his speech that was of concern and has continued to do so. The pt has no history of ENT (ear, nose, throat) problems; he recently had undergone a full audiological assessment. His inappropriate use of language such as I hungry. I''d better go to bed has been of concern. His mother suspected that he learned and recited verbatim and everything he did was parrot-fashion. He tended to find inappropriate uses for whatever he was given to play with. Formal assessment was not completed. He sat for a short while and attempted a number of tasks successfully. He then decided to get down from the table and left the room. Based on observation, his gross locomotor skills were probably age appropriate. He was a physically active, strong and energetic boy. Cognitive development appeared to be age appropriate. His personal/sociall skills were an area of concern. He dressed himself independently. He had an aversion to using the toilet and would hide when he needed to go. He could relate to other children but did not see the need for them. He paid no attention to visiting children and was very good at amusing himself. He was a messy eater. He was constantly up and down from the table during a meal and always had to dissect his sandwiches. He could use a spoon and fork independently. Hearing was within normal limits. There had been some discussion of language development earlier and of the pt''s sometimes-inappropriate use of language. He actively avoided fine motor tasks. He disliked drawing and avoided using a pencil as much as possible. In an assessment performed on 07/08/1996, a pediatrician indicated that the pt was diagnosed as having mild hydroureteronephrosis which was currently just being monitored and had no overt clinical effects. He had very mild asthma, which was well controlled. He used budesonide (PULMICORT) two puffs at night through a spacer. This was increased to two puffs in the jmorning and at night if he became wheezy. He also required albuterol (VENTOLIN) two puffs through a spacer if he became wheezy. There were no concerns about his vision but he has not had formal testing to date. He seemed to pick up very tiny details of things both near and far. He always had a problem with stool retention but was improving with a behavioral program of going to the toilet every evening. He wore diapers at night and had an occasional accident but in general his toileting during the day was problem free. Due to his disinterest, he needed help with dressing and washing.The pt was receiving help with social communication and developing his imagination. He had an exceptional memory and tended to learn language often by rote. His ability with language made him sound very mature but if asked to give an account of an event, he might provide a disjointed account. He had difficulties with conversations as he made literal interpretations and found difficulty with turn taking. His abstract understanding was also likely to be impaired, although his understanding of physical concepts such as shape, size, and color might well be ahead of his peers. He had a little concept of fear or danger and needed to be supervised. He was recently started a trial of a gluten-free diet. An immunization history indicated that the pt was vaccinated with diphtheria, pertussis, tetanus toxoid, polio and haemophilus B conjugate on 11/11/1993, 12/07/1993 and 01/11/1994. Upon internal review the pt''s Asperger''s syndrome, Attention Deficit Disorder with Hyperactivity, and Lymphoid Modular Hyperplasia in the terminal ileum were considered to be other important medical events. No further information is available. A copy of the pt''s complete medical records is available upon request.


VAERS ID: 197850 (history)  
Form: Version 1.0  
Age: 12.0  
Sex: Female  
Location: Foreign  
Vaccinated:2002-11-26
Onset:2002-12-03
   Days after vaccination:7
Submitted: 2003-02-12
   Days after onset:71
Entered: 2003-02-19
   Days after submission:7
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK - / -

Administered by: Unknown       Purchased by: Unknown
Symptoms: Meningitis, Pyrexia, Sensation of heaviness
SMQs:, Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Noninfectious meningitis (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2002-12-08
   Days after onset: 5
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: NONE
Current Illness:
Preexisting Conditions: Hydrocephalus; meningoencephalitis
Allergies:
Diagnostic Lab Data: Serum measles IgG antibody on 12/8/02, comment: no results reported, measles; Serum measles IgM antibody on 12/8/02, comment: no results reported, measles; Serum mumps IgG antibody on 12/8/02, comment: no results reported, mumps; Serum mumps IgM antibody on 12/8/02, comment: no results reported, mumps; Serum rubella IgG antibody on 12/8/02, comment: no results reported, rubella; Serum rubella IgM antibody on 12/8/02, comment: no results reported, rubella; Autopsy: big, swollen, fluid-filled and slightly asymmetric brain with thick membrane and compressed under side, content of stomach found in air pathways,
CDC Split Type: WAES0302USA00230

Write-up: Information has been received from a health authority concerning a 12 year old female who on 11/26/02 was vaccinated with a dose of MMR II. It was noted that the pt had a history of "intern hydrocephalus and signs of meningioencephalitis," but the onset of these is unclear. There was no concomitant medication. Eight days after vaccination, on 12/3/02 the pt developed a fever. On 12/8/02 the pt died (cause of death not reported). Follow up information from the health authority indicated that on 12/3/02 the patient developed numbness in her arms and legs. On 12/7/02 the patient developed a fever up to 40.3C. After contact with a doctor, the patient received penicillin treatment (tablets). On 12/8/02 the patient continued to complain about the pain in her legs and arms, and she was vomiting. The patient''s temperature decreaed to 37.3C. The patient was examined by a doctor 1/2 hour before her death. The doctor said that the patient was able to walk in her room and one could talk to her. The results of the autopsy showed, big, swollen, fluid-filled and slightly asymmetric brain with thick membrane and compressed under side. The content of the stomach has been found in the air pathways. There were no other findings. Clinical examinations showed in both lungs insignificant presence of bacteria type haemophilus haemoliticus. Intestinal bacteries type pseudomas aeruginosa was present in the normal range. Antigen examination did not show presence of meningococs type A, B, and C or pneumococcal polysaccharide. The presence of borelia IgG and IgM had not been shown. Examinations of antibody against MMR viruses showed the presence of IgG and IgM against measles and IgM against mumps but not IgG. IT was not founded any signs or acute or earlier infections with measles virus or reaction on this infection. Neuropathological examinations showed chronic changes in the brain membrane as a result of coalescence of the frontal lobe with brain membrane and brain surface reminding inflamed cell infiltration. The pattern of cell infiltration occurred along cavity forms the typical glial scar. It was reported that the chances in the brain membrane had started at least a half hear ago or for several years ago. The health authority assessment indicated that the results of the autopsy and other examinations showed that compression of the brain causes death from lack of breathing or heart stop. The changes in the brain membrane indicated that earlier cerebrospinal memingitis resulted in the formation of a cavity. The assessment noted, it is unclear if the increased fluid content in the brain was the result of MMR vaccinatoin or infection, possible influenza. However, the results of the examinations showed that the most likely, the increased fluid in the brain and resulted compression of the brain was the consequence of virus infection during earlier cerebrospinal meningitis resulting in formation of cavity in the brain. Follow up information, in the form of an autopsy report, indicated that the patient developed afever and felt well on 12/3/02 on her way home from school. The family took it to be influenza, as a number of families had had it. On 12/8/02 the patient continued to get worse, vomiting and still complaining of a sensation of heaviness and pains in her arms and legs. Post mortem findings were: stomach contents found to have been sucked down into the airways, and an large, swollen, fluid-filled and slightly asymmetrical brain with thickened meninges and signs of pressure on the underside. No pathological changes otherwise. Additional examinations indicated that a full bacteriological examination was carried out, indicating only isolated bacteria of the type haemophilus haemoliticus in both lungs, and these were not attributed any significance. Cultures were taken for pathogenic intestinal bacteria, indicating the presence of naturally occurring pseudomonas aeruginosa. No antibodies were found for rubella. It was noted that the results for mumps antibodies were consistent with a recently administered vaccination, and no previous infection with rubella, or sign of reaction ot the administered vaccine was demonstrated. The neuropathological examination revealed chronic changes, with a thickened meninx and subsequent coalescence of the frontal lobes and attaching of the meninges to the surface of the brain, plus the presence of small inflammatory cell infiltrates. Isolated inflammatory cell infiltrates were observed around the vessels and along their cavities, plus the presence of scar tissue in the form of so-called gliosis. The changes were interpreted as an existing result of a previous inflammation in the meninges and brain tissue, which had taken place at least 5 years ago, or possibly more. Brain atrophy was demonstrated and an enlarged brain cavity wsa noted. Acute fluid accumulation was also found in the brain, with signs of the cerebrum having been pressed down around the brain stem. The conclusion was that, cause of death may be assumed to be respiratory and cardiac arrest resulting from downward pressure on the brain. It was noted that changes found in the brain indicated a past meningeal and brain inflammation, with a subsequently enlarged brain cavity. It was further noted that of relevance is the finding of pronounced fluid accumulation and subsequent downward pressure from this. The extent to which fluid accumulation in the brain was caused by MMR vaccine or an infection, possibly influenza, cannot be determined with certainty, but based on antibody determinations and culture results, it is most likely that fluid accumulation and subsequent downward pressure on the brain arose due to a viral infection in either the previously inflamed meninges or brain (which had occasioned an enlarged brain cavity), in an already weakened 12 year old girl. It was noted that the pt was examined for IgG and IgM for measles, mumps and rubella, but no results were reported. Additional information is not expected. Case closed.


VAERS ID: 199294 (history)  
Form: Version 1.0  
Age: 1.08  
Sex: Male  
Location: Foreign  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2003-03-07
Entered: 2003-03-12
   Days after submission:5
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK - / -

Administered by: Unknown       Purchased by: Unknown
Symptoms: Coma, Convulsion, Haemorrhage intracranial, Hypotonia, Thrombocytopenia, Vomiting
SMQs:, Acute pancreatitis (broad), Haematopoietic thrombocytopenia (narrow), Peripheral neuropathy (broad), Haemorrhage terms (excl laboratory terms) (narrow), Hyperglycaemia/new onset diabetes mellitus (broad), Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (broad), Haemorrhagic central nervous system vascular conditions (narrow), Convulsions (narrow), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Gastrointestinal nonspecific symptoms and therapeutic procedures (narrow), Hypotonic-hyporesponsive episode (broad), Generalised convulsive seizures following immunisation (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Hypoglycaemia (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: Imaging studies revealed subdural hemorrhage; physical examination flaccid and unresponsive; platelet count 50x10 to the 9/L
CDC Split Type: WAES0302CAN00126

Write-up: Information has been received from three physicians publishing an article titled "Thrombocytopenia after immunization of children, 1992 to 2001" concerning a 13 month old male who was vaccinated between 1992 to 2001 with MMR II. Subsequently the pt experienced thrombocytopenia and was hospitalized 6 days post therapy with MMR II. The authors reported that the pt was previously well but had fallen down a few stairs three days prior to hospitalization. On the day of admission the pt had vomited and had a seizure. A physical examination was done that revealed the pt to be flaccid and unresponsive. Subsequently, imaging studies of his head revealed a subdural hemorrhage and a blood platelet count of 5x10 to the 9/1. The pt was treated with four units of platelets, one dose of hydrocortisone and two doses of IV immunoglobulin. Within a few hours of being hospitalized the pt died. The authors felt that the cause of death was intracranial haemorrhage nos. No further info is available.


VAERS ID: 205367 (history)  
Form: Version 1.0  
Age: 1.6  
Sex: Female  
Location: Foreign  
Vaccinated:1982-01-05
Onset:1982-01-09
   Days after vaccination:4
Submitted: 2003-06-20
   Days after onset:7831
Entered: 2003-06-25
   Days after submission:5
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MM: MEASLES + MUMPS (MM-VAX) / MERCK & CO. INC. - / UNK - / -

Administered by: Unknown       Purchased by: Unknown
Symptoms: Convulsion, Electroencephalogram abnormal, Encephalitis, Laboratory test abnormal, Loss of consciousness, Mydriasis, Pyrexia
SMQs:, Torsade de pointes/QT prolongation (broad), Hyperglycaemia/new onset diabetes mellitus (broad), Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Arrhythmia related investigations, signs and symptoms (broad), Convulsions (narrow), Noninfectious encephalitis (narrow), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Hypotonic-hyporesponsive episode (broad), Generalised convulsive seizures following immunisation (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Hypoglycaemia (broad)

Life Threatening? Yes
Birth Defect? No
Died? Yes
   Date died: 1982-01-14
   Days after onset: 5
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: Assisted ventilation; EEG: severe general alterations; Intubation; Spinal tap unremarkable and 145/3 cells; Measles antibody negative, mumps antibody negative; Mycoplasma pneumoniae titer 1:16;Lymphatic structure biopsy: echo virus type V; Other virus titers negative; Body temp: fever; Clinical serology test: narrative; Body temp: 40C; Diagnostic lab test: othre virus titers negative; Autopsy: meningoencephalitis of middle grade extension; Diagnostic lab test: mycoplasma pneumoniae titer: 1:16; Lymphatic structure biopsy: Echo virus type V; Spinal tap: 145/3 cells; Intubation; EEG: severe general alterations; Spinal tap: unremarkable;
CDC Split Type: WAES0306USA01727

Write-up: Information has been received from two health professionals concerning a 19 month old female who in May 1982, was vaccinated with measles (+) mumps virus vaccine live. In May 1982, on the day of vaccination, the patient had serous rhinitis, but was in good general health. On the 6th day, the patient had a fever (value not reported). On the 7th day, the patient''s fever was 40 degrees C. On the 8th day, the patient developed unconsciousness with convulsions. The lumbar puncture was unremarkable. Subsequently, the patient developed deep coma. Her EEG noted severe general alterations. The patient required intubation and was placed in a respirator. On the 9th day, her pupils were fixed and dilated with muscular hyptonia. The lumbar puncture indicated 145/3 cells, virus serologic findings were negative. Subsequently, the patient died. A lymph node biopsy specimen detected Echo virus type V. The measles and mumps antibodies were negative as well as all other virus titers examined. The mycoplasma pneumoniae titer 1:16 section noted moderately distinct meningoencephalitis, signs of central death. The outcome of the meningoencephalitis was not reported. Upon internal review, meningoencephalitis was considered to be immediately life-threatening and an other important medical event (OMIC). No further information is available. A 15-day follow up report received 10/31/2003 adds: Additional info was received which reported the vaccination date as 01/05/1982. In addition, the pt was reported as a 15-month old female pt, with a slight respiratory infection and acute rhinopharyngitis, who was vaccinated with measles virus vaccine live (+) mumps virus vaccine live vaccine, 0.5 ml, subcutaneous administration. Concomitant medications included "analgesics/antirheumatics". Additional pt info included that the pt suffered from brain edema and subsequently, the pt was hospitalized. The date of death was reported as 01/14/1982. The autopsy revealed meningoencephalitis was considered to be immediately life-threatening and an other important event. In addition, the article discussed the experiences of 28 other patients (WAES #0305USA00689, WAES #0306USA01721 through WAES #0306USA01725 and WAES #0306USA01727 through WAES #0306USA01748). No further info is available. This article was identified during a review of the literature for MMR II. A copy of the English translation has been provided. A 15-day follow up report received 10/31/2003 adds no new info. Follow up on 01/09/04: "This is an amended report. The date of vaccination now reads 01/05/1982 instead of 01/05/1985."


VAERS ID: 209467 (history)  
Form: Version 1.0  
Age:   
Sex: Male  
Location: Foreign  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2003-09-17
Entered: 2003-09-22
   Days after submission:5
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
IPV: POLIO VIRUS, INACT. (NO BRAND NAME) / UNKNOWN MANUFACTURER - / UNK - / -
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK - / -

Administered by: Unknown       Purchased by: Unknown
Symptoms: Gastrooesophageal reflux disease
SMQs:, Gastrointestinal nonspecific dysfunction (narrow)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness:
Preexisting Conditions: Premature birth; Gastric disorder
Allergies:
Diagnostic Lab Data: UNK
CDC Split Type: WAES0309USA00381

Write-up: Information has been from an internet new site concerning a male infant, born prematurely at 28 weeks and suffers from a rare stomach disorder, who was vaccinated with a dose of MMR (second generation) (date unknown). Secondary suspect therapy included poliovirus vaccine inactivated (unspecified) (date unknown). The news report stated that "The patient who was born prematurely at 28 weeks suffered a rare stomach disorder. It meant that highly gastric contents entered his airways. But a top surgeon said that the infant suffered the unfortunate coincidence of undergoing immunization before he died while he was being bottle fed by his mother. A consultant neurosurgeon at a hospital, said he believed the immunization could have depressed the patient''s natural instinct to attempt to reject the milk. A pathologist from a hospital, said he was sceptical about any links between jabs and the death. But he said that the consultant neurosurgeon was better qualified to evaluate the risk than himself. On Tuesday, the Coroner recorded a verdict of accidental death after the patient, inhaled some gastric contents. She added: "I was thinking about recording the proximity of the immunization but probably it is too uncertain for me to say that. "But obviously, it is something important that health care practitioners will want to consider. File to be completed. Additional information is not expected.


VAERS ID: 212888 (history)  
Form: Version 1.0  
Age:   
Sex: Male  
Location: Foreign  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2003-11-17
Entered: 2003-11-25
   Days after submission:8
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK - / -

Administered by: Unknown       Purchased by: Unknown
Symptoms: Encephalitis
SMQs:, Noninfectious encephalitis (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: UNK
CDC Split Type: WAES0311USA01281

Write-up: Information has been received from a newspaper article. A male pt, with no reported relevant history, was vaccinated on an unspecified date with a dose of MMR II. The article reported that over the eighteen months following vaccination the p developed subacute sclerosing panencephaltiis and lost the ability to do everything. It was reported that the pt died at 18 years of age from subacute sclerosing panencephalitis. The exact date of death was not specified. No further info is available. Case is closed.


VAERS ID: 214003 (history)  
Form: Version 1.0  
Age: 2.7  
Sex: Female  
Location: Foreign  
Vaccinated:2003-02-28
Onset:2003-02-28
   Days after vaccination:0
Submitted: 2003-12-10
   Days after onset:285
Entered: 2003-12-16
   Days after submission:6
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. C2831 / UNK - / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Laboratory test abnormal, Neoplasm, Pyrexia, Sarcoma
SMQs:, Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Non-haematological malignant tumours (narrow), Non-haematological tumours of unspecified malignancy (narrow)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2003-11-27
   Days after onset: 272
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: NONE
Current Illness:
Preexisting Conditions: NONE
Allergies:
Diagnostic Lab Data: Ultrasound: there is a low echo area where an artery passes through. Diagnostic pathological examination: parvicellular malignant tumor probably originated from granulocytic sarcoma. Bone biopsy: eosinophilic granulocyte increased, neutrophil alkaline phosphatase increased. Body temp 38.5 C. WBC normal. Hemoglobin decreased. Lymphocyte count normal. Neutrophil count normal; Platelet count decreased.
CDC Split Type: WAES0312CHN00004

Write-up: Information has been received from a physician concerning a 34 month old girl who at 1:00 PM, 2/28/03 was vaccinated with MMR, 0.5 ml, IM. In the evening of 2/28/03, the girl experienced fever with 38.5 of body temperature. At 7:00 PM, 2/28/03, the girl developed a 0.5x0.5cm square of mass around her right ear. On 5/1/03, she was placed on fomentation therapy (detail unknown) for the treatment of the mass under doctor''s suggestion. On 3/25/03, the girl recovered from fever. On 4/29/03, the girl was hospitalized because the mass increased to 4x2cm square. The physical examination showed the mass was middle texture with clear borderline, coarse surface and limited mobility. At the time, the result of her blood examination revealed 7.7 of white blood cell count, 35.1 of blood lymphocyte count, 59.4 of blood neutrophil count, 2.7 of blood platelet count and 100 of blood hemoglobin. On the same day, her right ear ultrasound result showed there was a low echo area where an artery passes through. On 4/30/03, the girl was diagnosed with parvicellular malignant tumor in right parotid gland via diagnostic pathological examination. The physician estimated the parvicellular malignant tumor probably originated from granulocytic sarcoma in lymphatic and hematopoietic system. On 5/9/03, the result of her bone biopsy revealed her eosinophilic granulocyte and neutrophil alkaline phosphatase were increased. On 11/27/03, the girl died because of parvicellular malignant tumor in right parotid gland. The reporting physician felt the girl''s parvicellular malignant tumor in right glad region was definitely not related to the vaccination with MMR. Additional information is not expected.


VAERS ID: 216187 (history)  
Form: Version 1.0  
Age: 8.0  
Sex: Male  
Location: Foreign  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2004-02-03
Entered: 2004-02-09
   Days after submission:6
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / 1 UN / UN

Administered by: Unknown       Purchased by: Unknown
Symptoms: Drug ineffective, Heart rate increased, Hypotension, Hypoxia, Infection, Laboratory test abnormal, Pneumonia, Pyrexia, Rash papular, Respiratory disorder, Tachypnoea
SMQs:, Anaphylactic reaction (narrow), Asthma/bronchospasm (broad), Lack of efficacy/effect (narrow), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Arrhythmia related investigations, signs and symptoms (broad), Acute central respiratory depression (broad), Pulmonary hypertension (broad), Eosinophilic pneumonia (broad), Respiratory failure (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Infective pneumonia (narrow), Dehydration (broad), Hypokalaemia (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: Antineoplastic (unspecified)
Current Illness:
Preexisting Conditions: Acute lymphobalstic leukaemia; T-cell count decreased; chemotherapy
Allergies:
Diagnostic Lab Data: Chest x-ray: day 5: diffuse bilateral infiltrate; blood pressure measurement; chest x-ray: prominent interstitial pattern bilaterally, particularly mid and lower lung fields; immunofluorescence antigen testing both lungs: parainfluenza virus type 3 detected; bronchial irrigation: pending: fungal, mycobacterial, legionella, mycoplasma pneumoniae cultures; bronchial irritation: negative direct staining for bacteria, fungi, P carinii, acid-fact bacilli, Legionella pneumophila; renal function study: normal; endotracheal tube culture: coagulase-negative staphylococci; blood pressure measurement: hypotension; autopsy; chest x-ray: bilateral, diffuse mixed interstitial and airspace, SC emphysema most evident in left axilla; WBC count 11.2 x 10 9/L; absolute neutrophil count 8.6, 11,400/mm3; arterial blood O2 sat 94%; body temp 39.1 C, 40 C; hemoglobin 106 g/L; platelet count 44 x 10 9/L; vital sing 30 breaths/min; blood culture: negative; nasal culture: positive for parainfluenza virus type 3; wound culture: lip: herpes simplex type 1; serum L-lactate test: lactic acidosis; cytomegalovirus antibody screen: negative: urine and buffy coat; bronchial culture: bacterial culture negative; total heartbeat count 148 beats/min; hepatic function tests: normal; urine culture: negative.
CDC Split Type: WAES0401CAN00086

Write-up: Information has been received from a physicians publishing article, January 2004 titled "Fever and Respiratory Distress in an 8 year old boy Receiving Therapy for Acute Lymphoblastic Leukemia," "Measles Vaccination" concerning an 8 year old male with acute lymphoblastic leukaemia, T-cell count decreased and chemotherapy was in remission by day 28 and had received his last dose IV chemotherapy therapy 2 weeks prior hospitalization, who in approximately 1988 was vaccinated with MMR II. The boy was previously a healthy boy. In 1995, the pt was hospitalized in a local hospital with a history of fever for a week and tachypnea and respiratory distress for 24 hrs. Therapy with ceftazidime and topical therapy was initiated on his upper lip for a cold sore. Blood culture and urine culture were negative. At day 5 of hospitalization, the pt experienced persistent high fever, hypoxemia and a deteriorating mental status. A chest x-ray demonstrated diffuse bilateral infiltrates. The pt was transferred to a hospital. On admission to the hospital, the pt had the following vital signs: body temp: 39.1 C, heart rate: 148 beats/min; oxygen sat 94% on room air, blood pressure: 90/50mmHg. The pt''s ears were red, with fluids. Examination demonstrated dry, slightly red and crusty conjunctivae and few scattered petechiea, several slightly raised, slightly red papules on skin on hand and back. No lymphadenopathy or hepatosplenomegaly were noted. Liver and renal function were normal. The pt also had the following test results: Hemoglobin: 106g/l, white blood cell count: 11.2 x 10 9/L, absolute neutrophil count: 8.6, platelets: 44 x 10 9/L, chest x-ray: prominent interstitial pattern bilaterally, particularly in the mid and lower lung fields. Therapy with piperacillin, gentamicin and high dose of trimethoprim/ sulfamethoxazole was initiated followed by IV acyclovir the next day. The following day a nasopharyngeal swab demonstrated a positive result for Parainfluenza virus type 3. The pt was still febrile (40 C) 2 days later. The pt need in oxygen increased. The pt had an absolute neutrophil count of 11,400/mm3. The pt was admitted to the ICU and received bilevel-positive airway pressure. A bronchoalveolar lavage demonstrated negative staining for bacteria, fungi, Pneumocystis carinii, acid-test bacilli and Legionella pneumophila. Result were pending on fungal, mycobacterial and legionella and Mycoplasma pneumonia cultures. Immunofluorescence antigen testing on both lungs was positive Parainfluenza virus type 3. Herpes simplex type 1 was present in a scraping of the lip, coagulase-negative staphylococci grew on an endotracheal tube culture and urine and buffy coat were negative for cytomegalovirus. The pt was intubated 2 days later because of increasing hypoxia. Therapy with amphotericin-B was initiated empirically because of persistent fever and furosemide for positive fluid balance, decreased urinary output and ''wet-looking" lungs. Diffuse air space and interstitial disease with pneumomediastinum and SC emphysema, most evident in the left axilla were noted on chest x-ray the next day. Therapy with dopamine was initiated to maintain good perfusion, therapy with acyclovir was discontinued and therapy with ganciclovir was initiated. A second bronchoalveolar lavage confirmed the findings of the first one. The pt stayed febrile and was difficult to ventilate over the course of the next several days. The pt became more and more hypotensive and developed lactic acidosis despite liquid ventilation with a perfluorocarbon emulsion containing oxygen. Decision was made to not pursue further aggressive treatment and therapy with dopamine was discontinued. The pt died 18 days after hospitalization. An autopsy was performed. "The cause of death was clearly the recent measles infection causing the giant cell pneumonia with diffuse damage to the lining epithelium of the respiratory tract from trracheal to alveolar levels." The authors also stated that the "believed that the single dose of vaccine failed to protect our pt and possibly the sibling (see WAES0401CAN00087). We believed that the child with leukemia likely had depression of T-cell function as a result of chemotherapy" and further believe that he developed measles in part because he received only a single dose of vaccine, but that the infection proved fatal because of immunosupression." No further info is available.


VAERS ID: 222636 (history)  
Form: Version 1.0  
Age: 13.0  
Sex: Male  
Location: Foreign  
Vaccinated:2004-04-22
Onset:2004-05-04
   Days after vaccination:12
Submitted: 2004-06-11
   Days after onset:38
Entered: 2004-06-15
   Days after submission:4
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. D2499 / UNK - / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Acute leukaemia, Dizziness, Epistaxis, Gingival bleeding, Haematocrit decreased, Lymphadenopathy, Parotid gland enlargement, Platelet count decreased, Pyrexia, Red blood cell count decreased, Thrombocytopenia, Vomiting, White blood cell count increased
SMQs:, Acute pancreatitis (broad), Haematopoietic erythropenia (narrow), Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Haemorrhage laboratory terms (broad), Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Gingival disorders (narrow), Oropharyngeal conditions (excl neoplasms, infections and allergies) (narrow), Gastrointestinal nonspecific symptoms and therapeutic procedures (narrow), Vestibular disorders (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Haematological malignant tumours (narrow)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2004-05-12
   Days after onset: 8
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: Platelet count decreased; Bone marrow biopsy: marrow hyperplasia: I, Granulocyte count decreased to 4.5%, red blood cell count decreased to 3.5% and lymphocyte count increased to 92%; Blood pressure measurement 110/70; WBC increased; Hematocrit decreased; Hemoglobin normal; Lymphocyte count increased; Neutrophil count decreased; Basophil count 3.04; Eosinophil count 0.17; Monocyte count increased; HR: 96, sinus rhythm
CDC Split Type: WAES0406CHN00008

Write-up: Information has been received from an agency official concerning a 13 year old male who on approximately 4/22/04 was vaccinated with MMR, 0.5 ml, IM. On approximately 5/4/04, the boy experienced vomiting, dizziness, fever, lymph nodes swelling, teeth bleeding, nasal bleeding, parotid swelling and platelet count decreased (detail unknown). On 5/4/04, the boy was diagnosed with possible acute leukemia and was hospitalized. Subsequently (date unknown), the boy died. Follow up information was received from the reporting official on 6/4/04. It was on 4/21/04 that the boy was vaccinated with MMR, 0.5ml, IM. On approximately 4/25/04, the boy developed dizziness, weakness and vomiting without coffee-like contents and projective. On 5/2/04, the boy developed fever, rhinorrhoea and epistaxis and he was plaaced on therapies with fosfomycin and ibuprofen. Subsequently, he developed sternal pain, lymph nodes swelling and teeth bleeding when brushing. On 5/4/04, the boy was hospitalized. On the same day, the physical examination showed swelling of retruauricular lymph nodes, cervical lymph nodes, submaxillary lymph nodes, subaxillary lymph nodes and inguinal lymph nodes. The biggest lymph node was soybean-like, middle texture, movable and no tenderness. On 5/5/04, the bone marrow biopsy revealed level I of marrow hyperplasia, 4.5 of granulocute count, 3.5 of red blood cell count and 92 of lymphocyte count. The lymphoblast and prolymphocyte count was 80.5 and they were similar size, round or round-like, less volume of cytoplasm, bice color and opaque. Their nucleus was round and chromatin was crude. Pitting and fold could be observed and there were 2 to 4 nucleoli in some cells. On 5/8/04, the blood examination revealed 109.1 of white blood cells count, 0.246 of neutrophil count, 0.558 of blood lymphocyte count, 142 of blood hemoglobin, 29.4 of blood hematocrit and 70 of blood platelet count. On 5/9/04, he was placed on therapy with prednisone, 20mg three times a day. On 5/10/04, his blood examination showed 440.1 of white blood cell count, 3.93 of blood monocyte count, 0.17 of blood eosinophil leukocyte count, 3.04 of blood basophilic leukocyte count, 93.1 of lymphocyte count, 72.6 of blood hemoglobin, 25.0 of blood hematocrit, and 61 of blood platelet count. On 5/11/04, the boy developed pale face, restlessness, chest distress, and dyspnea. At that time, his BP was 110/70 and HR was 96 with sinus rhythm. On the same day, therapies with prednisone increased to 30mg three times a day and the boy was placed on therapy with dexamethasone, furosemide, and dopamine. At 4:33 PM, 5/12/04, the boy died of acute lymphocytic leukemia and respiratory failure. The physician considered respiratory failure was caused by acute lymphocyte leukemia and acute lymphocytic leukemia was definitely not related to the vaccination. This is an amended report. The US lot equivalent is 646344/0520N. Additional information is not expected. This is a corrected report, as amended.


Result pages: prev   24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42   next

New Search

Link To This Search Result:

https://www.medalerts.org/vaersdb/findfield.php?EVENTS=ON&PAGENO=33&VAX[]=MEA&VAX[]=MER&VAX[]=MM&VAX[]=MMR&VAX[]=MMRV&VAXTYPES[]=Measles&DIED=Yes&VAX_YEAR_HIGH=2018&VAX_MONTH_HIGH=11


Copyright © 2020 National Vaccine Information Center. All rights reserved.
21525 Ridgetop Circle, Suite 100, Sterling, VA 20166