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Found 472 cases where Vaccine targets Measles (MEA or MER or MM or MMR or MMRV) and Patient Died and Vaccination Date on/before '2018-11-30'

Case Details

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VAERS ID: 131605 (history)  
Form: Version 1.0  
Age: 10.0  
Sex: Male  
Location: Foreign  
Vaccinated:1999-10-21
Onset:1999-10-24
   Days after vaccination:3
Submitted: 1999-11-22
   Days after onset:29
Entered: 1999-12-01
   Days after submission:9
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK - / -

Administered by: Other       Purchased by: Other
Symptoms: Encephalitis, Infection
SMQs:, Noninfectious encephalitis (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations: ~ ()~~~In patient
Other Medications: unk
Current Illness: unk
Preexisting Conditions: unk
Allergies:
Diagnostic Lab Data: unk
CDC Split Type: WAES99111359

Write-up: p/vax pt exp meningoencephalitis;11/4/99 pt died;COD was infectious meningoencephalitis;


VAERS ID: 134580 (history)  
Form: Version 1.0  
Age: 1.0  
Sex: Female  
Location: Foreign  
Vaccinated:1999-12-08
Onset:1999-12-17
   Days after vaccination:9
Submitted: 2000-03-01
   Days after onset:75
Entered: 2000-03-07
   Days after submission:6
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEPA: HEP A (HAVRIX) / SMITHKLINE BEECHAM - / UNK - / IM
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK - / SC
MNC: MENINGOCOCCAL (MENINGITEC) / PFIZER/WYETH - / UNK - / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: CSF test abnormal, Convulsion, Hernia, Pneumonia
SMQs:, Systemic lupus erythematosus (broad), Convulsions (narrow), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Eosinophilic pneumonia (broad), Generalised convulsive seizures following immunisation (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Hypoglycaemia (broad), Infective pneumonia (narrow)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 1999-12-18
   Days after onset: 1
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness:
Preexisting Conditions:
Allergies:
Diagnostic Lab Data: Cerebrospinal fluid-protein rasied (1.2g/l)
CDC Split Type: 20000052892

Write-up: 9 days post vax, pt exp convulsions. Overnight neurological status worsened, pt died early 11/18. Cause of death: convulsion NOS. Post-mortem: bronchopneumonia, tonsillar herniation. Final brain post-mortem awaited. No further info avail.


VAERS ID: 154205 (history)  
Form: Version 1.0  
Age: 1.5  
Sex: Unknown  
Location: Foreign  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2000-06-08
Entered: 2000-06-14
   Days after submission:6
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK - / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: Lymphocytosis, Pneumonitis
SMQs:, Interstitial lung disease (narrow), Eosinophilic pneumonia (narrow), Hypersensitivity (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: Autopsy
CDC Split Type: WAES00060390

Write-up: Information has been received concerning a pt who at approximately 13 months old was vaccinated with MMR. Subsequently at 18 months old the pt died with a diagnosis of erythrophagocytic lymphohistiocytosis. Autopsy revealed a "giant cell pneumonitis". It was also noted that "measles RNA (presumably) was detected in lung tissue". Additional information has been requested.


VAERS ID: 158472 (history)  
Form: Version 1.0  
Age: 11.0  
Sex: Male  
Location: Foreign  
Vaccinated:2000-07-04
Onset:2000-07-05
   Days after vaccination:1
Submitted: 2000-08-01
   Days after onset:27
Entered: 2000-08-07
   Days after submission:6
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
DT: DT ADSORBED (NO BRAND NAME) / UNKNOWN MANUFACTURER - / 2 - / IM
IPV: POLIO VIRUS, INACT. (NO BRAND NAME) / UNKNOWN MANUFACTURER R10783 / 2 - / IM
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 121011A / 2 - / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Bacterial infection, Malaise, Sepsis
SMQs:, Sepsis (narrow)

Life Threatening? Yes
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications:
Current Illness:
Preexisting Conditions: Obesity, metabolic disorder
Allergies:
Diagnostic Lab Data: Autopsy revealed cause of death as pneumococcal sepsis.
CDC Split Type: WAES00072420

Write-up: This 11-year-old male received vaxs and one day post vax, became "severely ill (not specified) and was admitted to the hospital. Reanimation was unsuccessful and the pt died. An autopsy was performed that revealed a pneumococcal sepsis," which was the cause of death. Severe malaise was also considered life threatening event.


VAERS ID: 159871 (history)  
Form: Version 1.0  
Age: 13.0  
Sex: Male  
Location: Foreign  
Vaccinated:2000-03-27
Onset:2000-04-27
   Days after vaccination:31
Submitted: 2000-09-13
   Days after onset:139
Entered: 2000-09-19
   Days after submission:6
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK - / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: Convulsion
SMQs:, Systemic lupus erythematosus (broad), Convulsions (narrow), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Generalised convulsive seizures following immunisation (narrow), Hypoglycaemia (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2000-04-27
   Days after onset: 0
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: UNK
CDC Split Type: WAES00082984

Write-up: On 4/27/00, the pt collapsed and died from an unknown cause. No post-mortem was performed. The pt took no other drug within the past three months. The reaction text stated "Probably first fit but no clear evidence. Question was raised as the whether MMR is relevant to seizure. No further information is available.


VAERS ID: 165792 (history)  
Form: Version 1.0  
Age: 1.08  
Sex: Male  
Location: Foreign  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2001-02-06
Entered: 2001-02-13
   Days after submission:7
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK - / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: Aspiration, Dizziness, Gastritis, Hypotonia, Vomiting
SMQs:, Acute pancreatitis (broad), Peripheral neuropathy (broad), Anticholinergic syndrome (broad), Guillain-Barre syndrome (broad), Gastrointestinal nonspecific inflammation (narrow), Gastrointestinal nonspecific symptoms and therapeutic procedures (narrow), Vestibular disorders (broad), Hypotonic-hyporesponsive episode (broad), Generalised convulsive seizures following immunisation (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: sibling hx of flaccid attacks unrelated to vaccinations.
Allergies:
Diagnostic Lab Data: autopsy - aspiration of vomit caused by acute gastritis
CDC Split Type: WAES01012076

Write-up: 8 days post vax the parents noted flaccidity and faintness a few hours preceding the death, but the symptoms subsided immediately and the pt seemed entirely healthy when put to bed. Forensic autopsy disclosed the cause of death as aspiration of vomit caused by acute gastritis. No further information is available. No date of death available.


VAERS ID: 167085 (history)  
Form: Version 1.0  
Age: 1.5  
Sex: Male  
Location: Foreign  
Vaccinated:2001-02-21
Onset:2001-02-23
   Days after vaccination:2
Submitted: 2001-03-08
   Days after onset:13
Entered: 2001-03-15
   Days after submission:7
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 0615J / UNK - / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: Agitation, Bacterial infection, Blood pressure decreased, Brain oedema, Disseminated intravascular coagulation, Hepatomegaly, Hypotension, Hypoxia, Leukocytosis, Liver function test abnormal, Pyrexia, Sepsis
SMQs:, Liver related investigations, signs and symptoms (narrow), Anaphylactic reaction (broad), Asthma/bronchospasm (broad), Haemorrhage terms (excl laboratory terms) (narrow), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Dementia (broad), Embolic and thrombotic events, vessel type unspecified and mixed arterial and venous (narrow), Acute central respiratory depression (broad), Pulmonary hypertension (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Hyponatraemia/SIADH (broad), Hostility/aggression (broad), Haemodynamic oedema, effusions and fluid overload (narrow), Cardiomyopathy (broad), Eosinophilic pneumonia (broad), Respiratory failure (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (narrow), Hypoglycaemia (broad), Infective pneumonia (broad), Dehydration (broad), Hypokalaemia (broad), Sepsis (narrow)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2001-02-25
   Days after onset: 2
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: BP-50/30; temp-35C; pertinent blood results from this hospital were: WBC-33,000,000/liter (leukocytosis); lymphocytes-56%; neutrophils 34%; monocytes 9%; basophils 1%; "deranged" liver function tests; Nml ammonia and blood cultures showed coagulase neg staphylococci indentified as being skin contaminants; post mortem was being conducted on 2/25/01.
CDC Split Type: WAES01030189

Write-up: Information was received from a health professional concerning an 18 month old male who on 02/21/01, in the afternoon, was vaccinated with the MMRII. On 02/23/01, at 3 AM he was found in his bed "having a fit" with a temp of 40 degrees C. He was admitted to the hospital where he deteriorated rapidly. At 7:20 AM he was transferred to the pediatric ICU at another hospital. During his transfer, the child deteriorated and was described as "flat" and essentially brain dead on arrival. The anaesthetist suspected the patient may have "coned" (coning: axial displacement of the cerebellar tonsils through the foramen magnum) at that point. He was resuscitated by treatment with inotropes, antibiotics and ventilation. He had overwhelming sepsis with DIC. He was ventilated from 02/24/01 in the AM. On 02/25/01 the ventilator was switched off and the patient died. The cause of death was bacterial sepsis and disseminated intravascular coagulopathy. A post mortem was being conducted on 02/26/01. This information was received by Aventis Pasteur MSD manufacturer # UK011318. On F/U, the post mortem conducted on 2/26/01 revealed large swollen liver, clear meninges and a swollen brain. The cause of death was established as sepsis and a microscopic exam of the lung showed a 2 day old bronchopneumonic condition. No organism has yet been identified. It was reported that the family history is significant for a similar episode in sibling (did not report if related to a certain vaccination). The mother had 5 pregnancies, of which only 2 children remain. One was a stillbirth at term. One was a 4.5 year old child who died during a "fit" of a very rare degenerative brain condition (Otoharan syndrome). This is an amended report. The batch number HK45610 has been added to the narrative.


VAERS ID: 174275 (history)  
Form: Version 1.0  
Age: 5.0  
Sex: Female  
Location: Foreign  
Vaccinated:1999-10-08
Onset:1999-10-11
   Days after vaccination:3
Submitted: 2001-08-03
   Days after onset:662
Entered: 2001-08-14
   Days after submission:11
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK - / SC
YF: YELLOW FEVER (NO BRAND NAME) / UNKNOWN MANUFACTURER - / UNK - / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: Alanine aminotransferase increased, Anaemia, Anorexia, Aspartate aminotransferase increased, Cardio-respiratory arrest, Dehydration, Diarrhoea, Hyperaemia, Hyperbilirubinaemia, Hyperchromic anaemia, Hypochromic anaemia, Hypotension, Infection, Interstitial lung disease, Laboratory test abnormal, Prostration, Pruritus genital, Pyrexia, Respiratory distress, Tachypnoea, Vomiting, Vulval disorder
SMQs:, Torsade de pointes/QT prolongation (broad), Liver related investigations, signs and symptoms (narrow), Cholestasis and jaundice of hepatic origin (narrow), Anaphylactic reaction (narrow), Acute pancreatitis (narrow), Asthma/bronchospasm (broad), Haematopoietic erythropenia (broad), Hyperglycaemia/new onset diabetes mellitus (broad), Interstitial lung disease (narrow), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Arrhythmia related investigations, signs and symptoms (broad), Shock-associated circulatory or cardiac conditions (excl torsade de pointes) (narrow), Pseudomembranous colitis (broad), Acute central respiratory depression (broad), Biliary system related investigations, signs and symptoms (narrow), Biliary tract disorders (narrow), Gastrointestinal nonspecific symptoms and therapeutic procedures (narrow), Eosinophilic pneumonia (broad), Hypersensitivity (broad), Noninfectious diarrhoea (narrow), Respiratory failure (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Infective pneumonia (broad), Dehydration (narrow), Hypokalaemia (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 1999-10-16
   Days after onset: 5
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications:
Current Illness:
Preexisting Conditions: Aseptic meningitis; bronchitis; diarrhea; low birth weight
Allergies:
Diagnostic Lab Data: Biopsy-diffuse interstitial infiltrate; neurological exam of CSF-nml: WBC-12,000/L; hematocrit-34%; serum aspartate aminotransferase-114 IU/L; total serum bilirubin-18.8 umol/L; serum immunoglobulin M test-neg. WBC count 12000. Post-mortem bx-histopathological exam revealed changes consistent with those seen in wild-type yellow fever; serum protein electrophoresis was positive for yellow fever virus
CDC Split Type: WAES01077925

Write-up: Information has been received from a physician concerning a 5 year old white female who on 10/8/99 was vaccinated with MMRII and was given a simultaneous but separate vaccine of yellow fever virus vaccine live. Three days, post vax, the pt developed a fever (39.6C) and diarrhea, and the next day, anorexia, vomiting and vulva pruritus and was seen in the ER. On exam, the pt was tachypenic, had a hyperemic pharynx, was anemic (hematocrit 34%) and had raised serum aminotransferase concentrations (aspartate aminotransferase 114 IU/L, alanine aminotransferase 160 IU/L), bilirubin concentration was slightly raised (18.9 umol/L). On the 4th day, the pt had prostration, respiratory distress, increased vomiting and diarrhea, dehydration and scleral icterus. Abdominal exam revealed enlarged, tender liver. Possible meningismus was noted. Differential dx of pneumonia and meningitis was added. CSF exam was normal. CXR revealed diffuse interstitial infiltrate in the left lung. The hematocrit fell to 30%, total leucocyte count was 12,000/L. The next day, the pt was admitted to ICU and was hypotensive, not perfusing, cyanotic, in acute respiratory distress. The pt had a cardiorespiratory arrest, was resuscitated but died within the next hour. On 10/16/99, the pt died. The cause of death was yellow fever. A meeting of yellow fever experts was convened in May 2000 and the panel unanimously concluded that the vaccine virus was the probable cause of fatal infections, which closely resembled wild-type yellow fever. Additional information is not expected.


VAERS ID: 177571 (history)  
Form: Version 1.0  
Age: 1.08  
Sex: Female  
Location: Foreign  
Vaccinated:1992-05-20
Onset:1999-01-15
   Days after vaccination:2431
Submitted: 2001-11-06
   Days after onset:1026
Entered: 2001-11-12
   Days after submission:6
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MEA: MEASLES (ATTENUVAX) / MERCK & CO. INC. - / UNK - / SC

Administered by: Other       Purchased by: Other
Symptoms: Apraxia, CSF test abnormal, Disturbance in attention, Dysarthria, Dyskinesia, Electroencephalogram abnormal, Encephalitis, Hyperglobulinaemia, Hyperreflexia, Immunoglobulins increased, Personality change, Repetitive speech, Strabismus, Syncope, Tremor
SMQs:, Torsade de pointes/QT prolongation (broad), Neuroleptic malignant syndrome (broad), Arrhythmia related investigations, signs and symptoms (broad), Dementia (broad), Dyskinesia (narrow), Parkinson-like events (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (narrow), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Hostility/aggression (broad), Cardiomyopathy (broad), Conditions associated with central nervous system haemorrhages and cerebrovascular accidents (broad), Depression (excl suicide and self injury) (broad), Ocular motility disorders (narrow), Hypotonic-hyporesponsive episode (broad), Hypersensitivity (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Hypoglycaemia (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: Failure to thrive; respiratory tract infection NOS
Allergies:
Diagnostic Lab Data: 10/99; Blood test-elevated (34,000 IU/ml or hyperglobulinorrachia) IgG antibodies to measles in serum: more than 325 IU/ml is positive; Clinical exam revealed increased osteo-tendinous reflexes in the right leg, dysarthria, perseveration, vismoconiructive apraxia and writing difficulties; Romberg''s test-pos: EEG-slow waves and diffuse delta-activity with periodic slow wave complexes time-locked to synchronous generalized myoclonic jerks on video: CSF-oligoclonal banks of immunoglobulins and elevated IgG antibodies to measles virus (14,000 mIU/ml, Bochringer Elisa processor) and in serum.
CDC Split Type: WAES01104436

Write-up: An 8 1/2 year old girl was admitted to out hospital with mild tremor of the right hand and mouth for 3 months and occasional drop attacks. At school, the teacher noticed an altered writing pattern, diminished concentration, declining results and changes in behaviour. We managed to observe the mild tremor described by the mother and we clearly saw myoclonic jerks of the mouth and neck together with eye deviation to the right. The girl was born in the Philippines. Her Belgian parents adopted her in 10/92 at an age of 1 year and 2 months. There is little known about her 1st period of life except that she was hospitalized shortly before the adoption for a severe lung infection and failure to thrive. She received the essential vaccinations including MMR on 5/20/92. Although vaccination against measles virus was administered at 9 months of age, which is common in endemic areas, the dx of SSPE (Subacute sclerosing panencephalitis) based on the clinical presentation and disease progression. The initial treatment with valproate acid showed no beneficial effect on the myoclonic jerks. Therapy therefore was changed to carbamazepine with temporary improvement. One month after the dx, Isoprinosine (2000 mg/day) was added. After a disease progression of 7 months, the girl died in a vegetative state. F/U 8/2/02 states: The reporters noted that SSPE in vaccinated individuals had been reported before and that these cases were probably attributed to vaccine failure, not to the attenuated vaccine virus. No further information is available.


VAERS ID: 178961 (history)  
Form: Version 1.0  
Age: 1.3  
Sex: Male  
Location: Foreign  
Vaccinated:2001-10-15
Onset:2001-10-20
   Days after vaccination:5
Submitted: 2002-01-30
   Days after onset:102
Entered: 2001-12-13
   Days after submission:48
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / 1 LA / SC

Administered by: Other       Purchased by: Other
Symptoms: Abnormal behaviour, Cyanosis, Eye disorder, Hypoxia, Laboratory test abnormal, Neurological symptom, Pyrexia, Respiratory distress, Vomiting
SMQs:, Anaphylactic reaction (broad), Acute pancreatitis (broad), Asthma/bronchospasm (broad), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Dementia (broad), Acute central respiratory depression (broad), Psychosis and psychotic disorders (broad), Pulmonary hypertension (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Gastrointestinal nonspecific symptoms and therapeutic procedures (narrow), Hostility/aggression (broad), Corneal disorders (broad), Eosinophilic pneumonia (broad), Retinal disorders (broad), Hypotonic-hyporesponsive episode (broad), Hypersensitivity (broad), Respiratory failure (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Infective pneumonia (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2001-10-27
   Days after onset: 7
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: Varicella
Allergies:
Diagnostic Lab Data: Radiology-revealed b/l fleecy pneumopathy; ophthalmologica exam-did not follow light (papilla with pale coloration); arterial blood gas measurement-hypoxamia reacting to oxygen w/0 hypercapnia; total heartbeat count-tachycardia; CSF glucose-glycorrachia; cerebrospinal fluid total protein test-proteinorrhachia; cerebrospinal fluid culture-sterile
CDC Split Type: WAES01113361

Write-up: Information has been received from a health professional concerning a 16 month old male who in 11/01 was vaccinated in the left arm with a 1st dose of MMRII. Five days, post vax, the child experienced a fever and breathing disorder. Then, within the following night, his respiratory disorder was aggravated and in the morning he presented with cyanosis, respiratory distress and neurological trouble (shifty eyes). He was hospitalized, received oxygen and was ventilated. A few days later, he died. The dx was acute respiratory distress syndrome probably of viral origin. The exact cause of death was not specified. It was noted that he had received previous immunizations without any problem. No autopsy was performed. No further information is available. Follow-up info from the hospital medical record indicated that the boy was the third child of a three children family in good general state of health and was born at 36.5 weeks of amenorrhea. He experienced varicella in July 2001. He received his MMR on 10/15/2001. The infant did not present with any pathology and had an excellent psychomotor development. The first symptoms appeared on 10/20/2001 with febrile syndrome and respiratory troubles associated with a laryngitis treated with homeopathy. On 10/21/2001, two episodes of post food vomiting occurred and the child was cyanotic and dyspneic when he woke up. The prarents described their child as absent and with an altered behavior. There was no notion of head injury or drug poisoning. He received prednisone and epinephrine and was transferred to an intensive care unit. Upon admission, hemodynamic was correct, saturometry (83%) at ambient temperature. He received oxygen by nasal route and saturation reached 92-93%, fever was at 40 deg. C, tachycardia at 180/min. There was also dyspnea., absence of ocular following intermittent strabismus, obnibulation and peripheral hypertonia. The ENT examination was normal. Thorax radiography revealed a bilateral fleecy pneumopathy. Arterial garometry showed hypoxemia reacting to oxygen without any hypercapnia. The first diagnosis was the following: infectious pneumopathy associated with an infectious or hypoxic encephalopathy. During hospitalization, pulmonary lesions aggravated with stubborn hypoxemia and signs of typical and severe acute respiratory distress syndrome which necessitated intubation, ventilation controlled with enalgesic sedation and curarisation. Pneumothorax right then left were drained by pleurocath. A diffuse, generalized ventilated received antibiotics and received dobutamine after placement of a central venous route and azots monoxide. The child was transferred to another intensive care unit on the fifth day of care for severe SDRA (azote monoxide dependent) and a therapy with oscillator and respiratory assistance were introduced. On 10/27/2001 the child died. In conclusion, the child experienced an acute respiratory distress syndrome, probably secondary to an infectious pulmonary pathology, from probable viral origin. It was not possible to distinguish a hypoxic encephalopathy secondary to the SDRA and a viral infectious encephalitis. Serum and CSF were still available. No further info is available.


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