Found 472 cases where Vaccine targets Measles (MEA or MER or MM or MMR or MMRV) and Patient Died and Vaccination Date on/before '2018-11-30'

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VAERS ID: 360751 (history)   Form: Version 1.0   Age: 1.04   Sex: Male   Location: Michigan   Vaccinated: 2009-10-01 Onset: 2009-10-04    Days after vaccination: 3 Submitted: 2009-10-08    Days after onset: 4 Entered: 2009-10-14    Days after submission: 6 Vaccin­ation / Manu­facturer Lot / Dose Site / Route FLU3: INFLUENZA (SEASONAL) (FLUZONE) / SANOFI PASTEUR UT3178DA / 1 RL / UN HEPA: HEP A (HAVRIX) / GLAXOSMITHKLINE BIOLOGICALS AHAVB334BA / 1 LL / UN HIBV: HIB (ACTHIB) / SANOFI PASTEUR UF673AA / 4 RL / UN MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 0554Y / 1 LL / UN VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. 0731Y / 1 RA / UN Administered by: Private       Purchased by: Unknown Symptoms: Death SMQs: Life Threatening? No Birth Defect? No Died? Yes    Date died: 2009-10-04    Days after onset: 0 Permanent Disability? No Recovered? No Office Visit? No ER Visit? No ER or Doctor Visit? No Hospitalized? No Previous Vaccinations: Other Medications: Current Illness: none Preexisting Conditions: Seizure disorder; DANDY WALKER syndrome Allergies: Diagnostic Lab Data: CDC Split Type: Write-up: Patient was seen on 10/1/09. Death reported on 10/4/09. Pt has seizure disorder along with encephalocele. / DANDY WALKER Syndrome. Had received vaccines on 10/1/09.

VAERS ID: 366004 (history)   Form: Version 1.0   Age: 1.0   Sex: Female   Location: New York   Vaccinated: 2009-08-12 Onset: 2009-09-01    Days after vaccination: 20 Submitted: 2009-11-06    Days after onset: 66 Entered: 2009-11-09    Days after submission: 3 Vaccin­ation / Manu­facturer Lot / Dose Site / Route MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 1580X / 1 RA / UN PNC: PNEUMO (PREVNAR) / PFIZER/WYETH D39016 / 4 LA / UN VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. 0043Y / 1 LA / UN Administered by: Private       Purchased by: Public Symptoms: Death, Pneumonia, Polymerase chain reaction, Rash, Respiratory disorder SMQs:, Anaphylactic reaction (broad), Acute central respiratory depression (broad), Eosinophilic pneumonia (broad), Hypersensitivity (narrow), Respiratory failure (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Infective pneumonia (narrow) Life Threatening? No Birth Defect? No Died? Yes    Date died: 2009-11-02    Days after onset: 62 Permanent Disability? No Recovered? No Office Visit? No ER Visit? Yes ER or Doctor Visit? No Hospitalized? Yes, 57 days    Extended hospital stay? Yes Previous Vaccinations: Other Medications: Ferrin-sol; Poly-vi-sol; NYSTATIN PRN; Bactroban PRN Current Illness: See 19, Had mild cough, otherwise well Preexisting Conditions: Milk protein allergy; Chromosomal abnormality; Hypotonia (abnormal muscle biopsy); Disordered feeding; Aspiration pneumonia (recurrent); Anemia; G-tube feed 12/9/09 Received records. PMH: RAD, GERD, type 2 muscle atrophy, anemia, multiple hospitalizations for aspiration pneumonia, RSV, G-tube, otitis media, varicella Allergies: Diagnostic Lab Data: DOH did evaluation; PCR (+) for vaccine strain (isolated from fluid from skin lesions). 11/13/09 Death Certificate received DOD 11/2/09 Cause of Death: Multisystem Organ Failure, Acute Respiratory Distress Syndrome, Varicella Pneumonitis. 12/9/09 Received records. Diag/Labs: CBC abnormal, CXR(-), chemistry abn, CRP 1(H), sed rate 35(H), blood cult(-), tracheal aspirate cult (+)gram neg bacilli, pseudomonas aeruginosa 1/4/09 Additional diag/labs received from date 9/5/09 to 10/29/09. Diag/Labs: CBC w/ diff abnormal, blood culture(+)pseudomonas aeruginosa, urine cult(+)candida albicans, Immune tests: abs T cells 223(L), abs suppressor 46(L), abs helper 169(L), IGG subclass 1-4(L), CXR (+)rt side pneumothorax, abdominal US(-), brain US(-). CDC Split Type: Write-up: Patient given vaccine on 8/12/09. Hospitalized for respiratory illness/pneumonia 8/27-9/1, given steroids during hospitalization. Rash developed on 9/1/09, day of discharge. Saw patient on 9/2/09, started on oral acyclovir. DOH and hospital notified. 11/13/09 Death Certificate received DOD 11/2/09 Cause of Death: Multisystem Organ Failure, Acute Respiratory Distress Syndrome, Varicella Pneumonitis. 12/9/09 DC summary received for dates 8/27/09. DX: respiratory difficulty, bronchospasms, hypotonia. Chief c/o respiratory distress, URI x1day, fever, tachypnea, retractions. Caretaker reports pt having difficulty breathing, fever, irritable. Assessment, (+)fever, grunting, retractions, hypotonia, O2 sat 91% on 3LNC. Speech and swallow eval: oropharyngeal dysphagia. Pt improved over 3 days, stable at dc. ER/hospital 9/5/09 to 10/29/09. DX: muscular weakness disorder, viral pneumonitis, varicella. Resp distress, fever. Parent states varicella vax 8/12/09. Varicella skin rash formed 8/31/09.EMS presented pt. to ER. Assessment: stridor, rash, fever, mild distress. Pt admitted and following day resp distress increased, grunting, increase in fever 103F, pt found to be irritable, O2 sats 92% w/ O2 therapy. Tylenol given, within 30 min temp 104.5F. One hr later pt HR 220-240bpm. Pt later stabilized but prognosis guarded.

VAERS ID: 370987 (history)   Form: Version 1.0   Age: 1.69   Sex: Male   Location: Colorado   Vaccinated: 2006-11-22 Onset: 2006-11-30    Days after vaccination: 8 Submitted: 2009-11-23    Days after onset: 1089 Entered: 2009-12-01    Days after submission: 8 Vaccin­ation / Manu­facturer Lot / Dose Site / Route FLUX: INFLUENZA (SEASONAL) (NO BRAND NAME) / UNKNOWN MANUFACTURER - / UNK UN / UN MMRV: MEASLES + MUMPS + RUBELLA + VARICELLA (PROQUAD) / MERCK & CO. INC. 0522F / 1 UN / UN Administered by: Private       Purchased by: Private Symptoms: Blood test, Convulsion, Electroencephalogram, Encephalitis viral, Lumbar puncture, Nuclear magnetic resonance imaging, Pyrexia SMQs:, Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Convulsions (narrow), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Generalised convulsive seizures following immunisation (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Hypoglycaemia (broad) Life Threatening? Yes Birth Defect? No Died? Yes    Date died: 2009-10-07    Days after onset: 1041 Permanent Disability? Yes Recovered? No Office Visit? No ER Visit? Yes ER or Doctor Visit? No Hospitalized? Yes, 5 days    Extended hospital stay? No Previous Vaccinations: Long lasting crying and lump near shot~DTaP (no brand name)~1~0.00~Patient Other Medications: None Current Illness: None Preexisting Conditions: 12/04/09 DC summary for DOS received for DOS 09/09/09 ? 10/07/09. PMH: SZ disorder. Allergies: NKDA Allergies: Diagnostic Lab Data: EEG; MRI; Lumbar puncture; Blood work 12/04/09 DC summary for DOS received for DOS 09/09/09 ? 10/07/09. Lab and DX tests: ICP: 40-50; brain biopsy: negative; skin biopsy as part of autopsy. CDC Split Type: Write-up: Fever, seizure approximately 8 days after vaccines. Diagnosed with viral encephalitis at hospital. 12/03/09 Vac record received for DOS 11/22/09 12/22/09: Provisional Autopsy report received for date of exam 10/9/09. Findings: Clinical history of seizures; presented with status epilepticus and Influenza A (H1N1) positivity. A. Heavy lungs. B. Clinical hx. of encephalitis and brain herniation. C. Other findings: Heavy heart, pericardial effusion, hepatosplenomegaly. 12/04/09 DC summary for DOS received for DOS 09/09/09 ? 10/07/09. Final DX: Hypoxic ischemic encephalopathy Pt presented with seizure, rigors, tonic-clinic seizures. On neurological exam: febrile seizure, developed blown R pupil, diffuse cerebral edema, increased ICP; tx: hypertonic saline, pentobarbital, Tamiflu, Ativan, Dilantin, Manitol, serum sodium; Pt''s condition worsened and Pt was not responsive. Physician related cerebral edema to H1N1 influenza related encephalitis or metabolic disorders. Pt expired on 10/07/09.

VAERS ID: 371206 (history)   Form: Version 1.0   Age: 2.0   Sex: Male   Location: New York   Vaccinated: 2009-11-24 Onset: 2009-12-01    Days after vaccination: 7 Submitted: 2009-12-02    Days after onset: 1 Entered: 2009-12-02 Vaccin­ation / Manu­facturer Lot / Dose Site / Route DTAP: DTAP (TRIPEDIA) / SANOFI PASTEUR U2471AA / 4 RA / IM HIBV: HIB (ACTHIB) / SANOFI PASTEUR UT75AA / 4 RA / IM MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 0620Y / 4 LA / IM PNC: PNEUMO (PREVNAR) / PFIZER/WYETH D66586 / 1 LA / IM Administered by: Unknown       Purchased by: Unknown Symptoms: Autopsy, Cardiac arrest, Death, Resuscitation SMQs:, Torsade de pointes/QT prolongation (broad), Anaphylactic reaction (broad), Arrhythmia related investigations, signs and symptoms (broad), Shock-associated circulatory or cardiac conditions (excl torsade de pointes) (narrow), Acute central respiratory depression (broad), Cardiomyopathy (broad), Respiratory failure (broad) Life Threatening? No Birth Defect? No Died? Yes    Date died: 2009-12-01    Days after onset: 0 Permanent Disability? No Recovered? No Office Visit? No ER Visit? No ER or Doctor Visit? No Hospitalized? No Previous Vaccinations: Other Medications: Current Illness: No Preexisting Conditions: History of several febrile seizures 1 year ago. Normal EEG then. No seizures since then. Allergies: Diagnostic Lab Data: Unsuccessful resuscitation by EMS and Vassar Hospital ER. Was asystolic when EMS arrived. CDC Split Type: Write-up: Unexpected death. Patient was asymptomatic except for skipping lunch. Took his usual afternoon nap but expired during sleep. Autopsy today did not reveal a cause. 01/07/2010. Autopsy received. DOD 1201/2009. Cause of Death: 1. Undetermined. Manner of Death: Undetermined. Additional Information Abstracted: I. [History of Febrile Seizures]: Cerebral Edema and Congestion. II. Pulmonary Edema and Congestion. II. Postmortem Toxicology Results: A. Blood: 1. Atropine = 870 NG/ML. B. Vitreous Humor: 1. Sodium = 137 MEQ/L. 2. Potassium = 17.8 MEQ/L. 3. Chloride = Creatinine = 0.8 MG/DL. 5. Urea Nitrogen = 7 MG/DL. 6. Glucose = <20 MG/DL.

VAERS ID: 373588 (history)   Form: Version 1.0   Age:    Sex: Unknown   Location: Unknown   Vaccinated: 0000-00-00 Onset: 0000-00-00 Submitted: 2009-12-15 Entered: 2009-12-16    Days after submission: 1 Vaccin­ation / Manu­facturer Lot / Dose Site / Route MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / UNK UN / UN Administered by: Other       Purchased by: Other Symptoms: Death SMQs: Life Threatening? No Birth Defect? No Died? Yes    Date died: 0000-00-00 Permanent Disability? No Recovered? No Office Visit? No ER Visit? No ER or Doctor Visit? No Hospitalized? No Previous Vaccinations: Other Medications: Unknown Current Illness: Preexisting Conditions: Unknown Allergies: Diagnostic Lab Data: Unknown CDC Split Type: WAES0912USA01512 Write-up: Information has been received from a female consumer concerning her child who "over 10 years ago" was vaccinated with a dose of MMR II. The patient died after being given the vaccine. No further information is available.

VAERS ID: 382602 (history)   Form: Version 1.0   Age: 1.26   Sex: Female   Location: Oklahoma   Vaccinated: 2010-01-05 Onset: 2010-01-06    Days after vaccination: 1 Submitted: 2010-03-14    Days after onset: 67 Entered: 2010-03-14 Vaccin­ation / Manu­facturer Lot / Dose Site / Route HEPA: HEP A (VAQTA) / MERCK & CO. INC. 0950Y / 1 LG / IJ MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 0824Y / 1 LG / IJ VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. 1006Y / 1 LG / IJ Administered by: Private       Purchased by: Other Symptoms: Abasia, Abdominal distension, Aphasia, Condition aggravated, Decreased appetite, Dehydration, Lethargy, Somnolence, Staring, Vomiting, Weight decreased SMQs:, Acute pancreatitis (broad), Hyperglycaemia/new onset diabetes mellitus (broad), Anticholinergic syndrome (broad), Dementia (broad), Dystonia (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Gastrointestinal nonspecific symptoms and therapeutic procedures (narrow), Conditions associated with central nervous system haemorrhages and cerebrovascular accidents (broad), Hypoglycaemia (broad), Dehydration (narrow) Life Threatening? Yes Birth Defect? No Died? Yes    Date died: 2010-04-04    Days after onset: 87 Permanent Disability? No Recovered? No Office Visit? No ER Visit? Yes ER or Doctor Visit? No Hospitalized? Yes, 2 days    Extended hospital stay? No Previous Vaccinations: Severe Vomiting and spasm of body~Hep B (no brand name)~1~0.00~Patient Other Medications: Current Illness: Preexisting Conditions: Had previously been to the hospital for dehydration and vomiting about 2 weeks earlier...allergies suspected, but doctors could not find any other problem. Allergies: Diagnostic Lab Data: CDC Split Type: Write-up: Vomiting (up to 8 days later), lethargic, no appetite, dehydration, had to go back to the hospital for hydration. Stopped walking and talking and interacting with us. Stared into space, very droggy, wanted to sleep all the time; started losing weight and got a very distended abdomen, and loss of appetite. This has lasted for almost 3 full months, now.

VAERS ID: 382746 (history)   Form: Version 1.0   Age: 14.0   Sex: Male   Location: Michigan   Vaccinated: 2009-10-20 Onset: 2009-11-04    Days after vaccination: 15 Submitted: 2009-11-06    Days after onset: 2 Entered: 2010-03-16    Days after submission: 129 Vaccin­ation / Manu­facturer Lot / Dose Site / Route HEP: HEP B (ENGERIX-B) / GLAXOSMITHKLINE BIOLOGICALS AHBVB707AA / 2 RA / IM IPV: POLIO VIRUS, INACT. (IPOL) / SANOFI PASTEUR D0052 / 1 LA / SC MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 0153Y / 2 RA / SC MNQ: MENINGOCOCCAL CONJUGATE (MENACTRA) / SANOFI PASTEUR U3027AA / 1 RA / IM TDAP: TDAP (ADACEL) / SANOFI PASTEUR C3250AA / 1 LA / IM VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. 1046Y / 1 LA / SC Administered by: Public       Purchased by: Private Symptoms: Drug exposure during pregnancy, Foetal heart rate decreased, Unevaluable event SMQs:, Pregnancy, labour and delivery complications and risk factors (excl abortions and stillbirth) (narrow), Foetal disorders (narrow) Life Threatening? No Birth Defect? No Died? Yes    Date died: 2009-11-04    Days after onset: 0 Permanent Disability? No Recovered? No Office Visit? No ER Visit? No ER or Doctor Visit? No Hospitalized? No Previous Vaccinations: Other Medications: None Current Illness: None Preexisting Conditions: Developmental delay (severe); strabismus Allergies: Diagnostic Lab Data: Unknown CDC Split Type: Write-up: Unknown.

VAERS ID: 388098 (history)   Form: Version 1.0   Age: 1.01   Sex: Male   Location: Indiana   Vaccinated: 2010-04-19 Onset: 2010-04-28    Days after vaccination: 9 Submitted: 2010-05-19    Days after onset: 21 Entered: 2010-05-19 Vaccin­ation / Manu­facturer Lot / Dose Site / Route HEPA: HEP A (VAQTA) / MERCK & CO. INC. 1259Y / 1 RL / IM MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 1222Y / 1 RL / SC PNC13: PNEUMO (PREVNAR13) / PFIZER/WYETH D94433 / 4 LL / IM VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. 1405Y / 1 LL / SC Administered by: Private       Purchased by: Public Symptoms: Blood culture negative, Brain herniation, CSF culture negative, Chest X-ray abnormal, Chronic sinusitis, Computerised tomogram abnormal, Death, Electroencephalogram abnormal, End-tidal CO2 abnormal, Endotracheal intubation, Exposure to communicable disease, Herpes simplex serology negative, Hypocalcaemia, Intensive care, Lethargy, Listless, Livedo reticularis, Lumbar puncture, Meningitis, Mental status changes, Nystagmus, Peripheral coldness, Polymerase chain reaction, Poor peripheral circulation, Pupillary reflex impaired, Sepsis syndrome, Tonic clonic movements, Use of accessory respiratory muscles SMQs:, Rhabdomyolysis/myopathy (broad), Angioedema (broad), Dementia (broad), Convulsions (narrow), Acute central respiratory depression (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (narrow), Cardiomyopathy (broad), Depression (excl suicide and self injury) (broad), Vestibular disorders (broad), Ocular motility disorders (narrow), Generalised convulsive seizures following immunisation (broad), Chronic kidney disease (broad), Tumour lysis syndrome (broad), Respiratory failure (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Hypoglycaemia (broad), Infective pneumonia (broad), Sepsis (narrow) Life Threatening? Yes Birth Defect? No Died? Yes    Date died: 2010-05-04    Days after onset: 6 Permanent Disability? No Recovered? No Office Visit? No ER Visit? Yes ER or Doctor Visit? No Hospitalized? Yes, 6 days    Extended hospital stay? No Previous Vaccinations: Other Medications: none Current Illness: no Preexisting Conditions: hypospadius repair 1-22-2010 Allergies: Diagnostic Lab Data: Note: All result statuses are Final unless otherwise noted. Tests: (1) BLOOD CULTURE (BLC) Order Note: ! SPECIMEN DESCRIPTION "Result Below..." *1 RESULT: BLOOD(A) PERIPHERAL STICK ! SPECIAL REQUESTS "Result Below..." *2 RESULT: Peds bottle only received. ! CULTURE NO GROWTH 6 DAYS *3 ! REPORT STATUS FINAL *4 05042010 Note: An exclamation mark (!) indicates a result that was not dispersed into the flowsheet. Document Creation Date: 05/04/2010 8:21 AM CT HEAD WITHOUT CONTRAST Indication: Mental status changes, cyanotic, unresponsive Comparison: None Findings: The ventricles and CSF spaces are within normal limits. There is no acute hemorrhage, abnormal fluid collection or midline shift seen. No acute infarction or mass is seen. MRI may be helpful if symptoms persist. There are mild chronic sinusitis changes in the maxillary sinuses. Impression: 1. Mild chronic maxillary sinusitis changes. 2. Otherwise unremarkable for age. Note: All result statuses are Final unless otherwise noted. Tests: (1) HSV 1 AND 2 PCR QL (HSVPC) Order Note: ! HSV 1 NOT DETECTED NTD *1 ! HSV 2 NOT DETECTED NTD *2 This test was developed and its performance characteristics determined by Lab. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.Testing performed using real-time polymerase chain reaction (PCR) technology ! SOURCE "Result Below..." *3 RESULT: CEREBROSPINAL FLUID Note: An exclamation mark (!) indicates a result that was not dispersed into the flowsheet. Document Creation Date: 04/29/2010 1:22 AM Note: All result statuses are Final unless otherwise noted. Tests: (1) CSF CULTURE (CSFC) Order Note: ! SPECIMEN DESCRIPTION "Result Below..." *1 RESULT: CEREBROSPINAL FLUID ! SPECIAL REQUESTS "Result Below..." *2 RESULT: CEREBROSPINAL FLUID ! CULTURE NO GROWTH 5 DAYS *3 ! REPORT STATUS FINAL *4 05/03/2010 Note: An exclamation mark (!) indicates a result that was not dispersed into the flowsheet. Document Creation Date: 05/03/2010 7:40 AM Portable chest 4/28/2010 COMPARISON: None HISTORY: Shortness of breath COMMENT: The endotracheal tube is in satisfactory position on this single view. The patient is rotated. No effusion or pneumothorax is seen. The right lung appears grossly clear. There may be airspace disease in the left lung. IMPRESSION: Question left airspace disease. The right lung is grossly clear. The patient is rotated. Endotracheal tube appears satisfactory in this single view. CHEST XRAY BEDSIDE, Apr 28, 2010 02:52:39 PM INDICATION: Dyspnea There continue to be extensive areas of infiltrate predominately in the left upper lobe. The endotracheal tube is again noted. There has been apparent placement of an orogastric tube. The tip is located in the proximal portion of the thoracic esophagus. The right lung remains clear. IMPRESSION: 1. Presumed placement of an orogastric tube as discussed. 2. The study is otherwise unchanged from a study done earlier in the day. Reason For Initial Request: Pt Evidently, pt brought into ER on 4/28/10 for "Prolonged Seizure." Was intubated and transferred to another hospital. Currently, still intubated and determined significant hypoxia. Actions Taken Patient/Significant Other notified, MD notified Further Dialogue Received a call from resident Dr. Pt transferred from ER with Dx of meningitis. Per Dr, they think, pt had some sort of encephalopathy. Yesterday he had herniation of the cerebellar tonsils and pupils were not responding. Neurology consult was called in and an EEG done did not show any activity. After consultation with the relatives of the child it decided to withdraw life support and baby passed away last night. I appreciate Dr calling us and personally making us aware of this unfortunate incident. To Nurse PCC: kindly connect with parent/s to offer our condolence and to enquire if they need any help from us. 2 Failed attempts to reach mother at home. Reached Grma who will inform mother that we are aware and offering sympathy and assistance as needed. She does believe the list of support grief groups would be helpful and told we will mail in card to her. The Obituary will be listed tomorrow Friday, and services -12-2p 2pm Eulogy. Mother lives with son, and her father, also caregiver for pt. CDC Split Type: Write-up: CHIEF COMPLAINT: He presents here as a 12 month old that was brought in by mother, carried in from triage to shock room 2, lethargic and listless. HISTORY OF PRESENT ILLNESS: The patient, according to mother''s history, was exposed to several family members who have had URI symptoms over the last 24 hours and this morning he slept more than usual, walking up around 10:30 this morning, and was found to be lethargic. The patient was carried into shock room 2. Further history was not available. PAST MEDICAL HISTORY AND SURGICAL HISTORY: Negative. ALLERGIES: Negative. MEDICATIONS: Currently negative. REVIEW OF SYSTEMS: As per HPI; otherwise, all negative. PHYSICAL EXAMINATION: General: The patient was lethargic, listless, and unremarkable. HEENT: His oropharynx was clear. He did not have any tongue lacerations or abrasions. He had moist mucous membranes. Neck: Supple. I did not appreciate any obvious lymphadenopathy or meningeal signs. Lungs: Clear on auscultation. He had moderate accessory muscle use with intercostal retractions. Abdomen: Soft. I did not appreciate any distention or signs of trauma. Extremities: The lower extremity exam was cold to touch. He had poor perfusion. He was mottled. Neurologic: The patient had positive nystagmus and almost exhibited tonic-clonic-like activity. EMERGENCY DEPARTMENT COURSE: Immediately, we decided to intubate this patient to maintain a definitive airway. Using a 4.5 endotracheal tube that was uncuffed, I proceeded with intubation. A peripheral IV was inserted immediately by our nurse. I used 15 mg of IV succinylcholine with a dosing determined using a weight based scale. We believed the patient was anywhere from 10 to 12 kg. Once the patient was adequately paralyzed, I was able to successfully intubate this patient. He had positive end-tidal CO2 and condensation in the tube. He had blood work including a CBC, a blood culture, and a BMET. I had the patient transferred immediately to head CT which showed evidence of chronic maxillary sinusitis with no evidence of mass effect. When the patient returned back to the emergency room into shock room 2, I proceeded with spinal tap. Given the emergency situation, we did not have a chance to consent mother who was not immediately available. We went ahead and proceeded with the procedure. I was able to successfully perform a spinal tap using his pelvic crests as my landmarks. The entire procedure was performed under sterile conditions. The back was cleaned using iodine applied in circular fashion x3. Using the pediatric LP tray, and the spinal needle that was within the tray, I used the L3-L4 interspace to access the subarachnoid space. I was able to collect 3 tubes of CSF, at least 2 mL each, and these were sent for studies including HSV, PCR. We went ahead and ordered antibiotics including Rocephin 100 mg per kg IV. Laboratories returned with a white count 30.7, hemoglobin 14.0, platelet count 344. Sodium 153, potassium 6.9, chloride 113, CO2 of 10, BUN 88, creatinine 1.15, calcium 7.2. We are getting a BMET. I have ordered IV glucose, D25 2 mL/kg. A urine culture, and urinalysis, and a blood culture were ordered and pending. Postintubation chest x-ray showed left-air space disease. Right lung was clear. Endotracheal tube appeared to be in satisfactory position. Head CT did show evidence of chronic maxillary sinusitis. I spoke to Dr. from ICU and the patient will be transferred there in critical but stable condition. He asked that we go ahead and give him vancomycin 20 mg/kg IV as well as Acyclovir 20 mg per/kg IV, and I will also order maintenance IV fluids after receiving initial 200-mL normal saline bolus. We also gave him an ampule of calcium gluconate for his hypocalcemia. IMPRESSION: 1. Mental status changes. 2. Acute meningitis. 3. Sepsis syndrome. DISPOSITION: To ICU in critical but stable condition. CRITICAL CARE TIME: Exclusive of all procedures which included endotracheal intubation as well as spinal tape, greater than 60 minutes.

VAERS ID: 388916 (history)   Form: Version 1.0   Age: 1.06   Sex: Male   Location: Georgia   Vaccinated: 2010-01-07 Onset: 2010-01-28    Days after vaccination: 21 Submitted: 2010-05-13    Days after onset: 104 Entered: 2010-05-21    Days after submission: 8 Vaccin­ation / Manu­facturer Lot / Dose Site / Route FLU(H1N1): INFLUENZA (H1N1) (H1N1 (MONOVALENT) (SANOFI)) / SANOFI PASTEUR UP035BA / 2 UN / IM HEPA: HEP A (VAQTA) / MERCK & CO. INC. 1100Y / 1 UN / IM MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 0764Y / 1 UN / SC VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. 1229Y / 1 UN / SC Administered by: Private       Purchased by: Private Symptoms: Autopsy, Death, Endocardial fibroelastosis, Unresponsive to stimuli SMQs:, Hyperglycaemia/new onset diabetes mellitus (broad), Neuroleptic malignant syndrome (broad), Congenital, familial and genetic disorders (narrow), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Cardiomyopathy (broad), Hypotonic-hyporesponsive episode (broad), Hypoglycaemia (broad) Life Threatening? No Birth Defect? No Died? Yes    Date died: 2010-01-28    Days after onset: 0 Permanent Disability? No Recovered? No Office Visit? No ER Visit? No ER or Doctor Visit? No Hospitalized? No Previous Vaccinations: Other Medications: None Current Illness: None Preexisting Conditions: None Allergies: Diagnostic Lab Data: CDC Split Type: Write-up: Pt. received vaccines on 1/7/10 and was found unresponsive in crib on 1/28/10. Autopsy showed pt. died from Fibroelastosis of the heart.

VAERS ID: 404258 (history)   Form: Version 1.0   Age: 1.0   Sex: Female   Location: Nebraska   Vaccinated: 2010-10-11 Onset: 2010-10-18    Days after vaccination: 7 Submitted: 2010-10-18    Days after onset: 0 Entered: 2010-10-19    Days after submission: 1 Vaccin­ation / Manu­facturer Lot / Dose Site / Route FLU3: INFLUENZA (SEASONAL) (FLUZONE) / SANOFI PASTEUR UT3566BA / UNK RL / IM HEPA: HEP A (HAVRIX) / GLAXOSMITHKLINE BIOLOGICALS AHAVB441BA / UNK LL / IM MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 0647Z / UNK RL / IM VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. 0552Z / UNK LL / IM Administered by: Private       Purchased by: Private Symptoms: Apnoea, Death, Pulse absent, Resuscitation SMQs:, Shock-associated circulatory or cardiac conditions (excl torsade de pointes) (narrow), Acute central respiratory depression (narrow), Respiratory failure (narrow) Life Threatening? No Birth Defect? No Died? Yes    Date died: 2010-10-18    Days after onset: 0 Permanent Disability? No Recovered? No Office Visit? No ER Visit? No ER or Doctor Visit? No Hospitalized? No Previous Vaccinations: Other Medications: TYLENOL Children''s PO; QVAR 80, 1 inhaler, 10/14/2010, take 2 puffs by inhalation twice daily while awake; DIFLUCAN 10 MG/ML susr, 14 day supply, 10/11/2010, take 5 mL by mouth daily. Take 5 mls on day 1, then take 2.5 mls on days 2-14, or Current Illness: None Preexisting Conditions: Multiple congenital anomalies; Developmental delay; Esophageal reflux; Pneumonia, organism unspecified; Prematurity 36 weeks EGA; Hypothyroidism; Hypothalamic dysplasia; Bicuspid aortic valve; Oral thrush; Decreased sensation larynx; Stridor; GERD; Feeding difficulty; Dysphagia, pharyngeal Allergies: Diagnostic Lab Data: None CDC Split Type: Write-up: Patient was found pulseless and apneic in her bed by mom in the morning (0500). CPR performed and pt taken to ED. Unable to resuscitate.

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