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Found 781 cases where Vaccine is HPV4 and Life Threatening

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VAERS ID: 262735 (history)  
Form: Version 1.0  
Age: 16.0  
Sex: Female  
Location: Mississippi  
Vaccinated:2006-07-31
Onset:2006-08-13
   Days after vaccination:13
Submitted: 2006-09-07
   Days after onset:25
Entered: 2006-09-07
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0697F / 1 GM / IM
MNQ: MENINGOCOCCAL CONJUGATE (MENACTRA) / SANOFI PASTEUR 42107AA / 1 GM / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Guillain-Barre syndrome, Hypoaesthesia, Paraesthesia, Proteinuria, Red blood cell sedimentation rate increased
SMQs:, Acute renal failure (broad), Peripheral neuropathy (narrow), Systemic lupus erythematosus (broad), Guillain-Barre syndrome (narrow), Demyelination (narrow), Chronic kidney disease (broad), Proteinuria (narrow), Tubulointerstitial diseases (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, 5 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications:
Current Illness:
Preexisting Conditions:
Allergies:
Diagnostic Lab Data: MRI of brain, cervical, thoracic and lumbosacral spine, drug screen, pregnancy test, sed rate, Blood count, blood chemistries, Lumbar Puncture.
CDC Split Type:

Write-up: Vaccine was given on July 31 2006. She began having numbness and tingling in her feet and hands on or around August 13th or 14th, which persisted and slightly worsened until she was seen in our office on August 21st. Her neurological examination was normal, she had an elevated sedimation rate (39), mild protienuria, otherwize normal labs. MRI of her lumbosacral spine showed a (possibly old, chronic) subarachnoid cyst. She was referred to a neurologist and was seen on August 25th and was found to have weakened severely and was admitted to PICU for suspected Guillian-Barre syndrome which was confirmed by lumbar puncture. She was treated with IVIG with rapid improvement and has gone home. She is slowly improving and has residual weakness. Medical records including neurology received/reviewed. Final diagnosis is GBS. Was treated with IVIG as indicated on VAERS form. Per records pt has residual weakness. 12/19/06-progress notes received for and DC Summary DC DX: GBS.


VAERS ID: 267288 (history)  
Form: Version 1.0  
Age: 25.0  
Sex: Female  
Location: Maryland  
Vaccinated:2006-09-29
Onset:2006-09-30
   Days after vaccination:1
Submitted: 2006-11-15
   Days after onset:46
Entered: 2006-11-20
   Days after submission:5
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0800F / 1 UN / -

Administered by: Other       Purchased by: Other
Symptoms: Throat tightness, Tongue oedema, Urticaria
SMQs:, Anaphylactic reaction (narrow), Angioedema (narrow), Oropharyngeal allergic conditions (narrow), Oropharyngeal conditions (excl neoplasms, infections and allergies) (narrow), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? Yes
Recovered? Yes
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Yasmin, Macrobid
Current Illness: Urinary tract infection
Preexisting Conditions:
Allergies:
Diagnostic Lab Data:
CDC Split Type: WAES0611USA03232

Write-up: Information has been received from a physicians assistant concerning a 25 year old female who on 9/29/06 was vaccinated with a first dose of HPV vaccine. Concomitant suspect therapy initiated a few days prior included nitrofurantoin (Macrobid) for the treatment of a urinary tract infection (dose not reported). Other concomitant therapy included drospirenone + ethinyl Estradiol (Yasmin). On 9/20/06 the pt called the physicians office to state that she had developed hives. The physicians office referred her to the ER where she was placed on methylprednisolone (Medrol Dosepak). The pt was not hospitalized. On 10/2/06 the pt called the physicians office to report that her tongue was swelling and her throat was closing. The pt was immediately referred to the ER where she was given epinephrine (Epi Pen). The pt was not hospitalized. On 1/04/06 the pt recovered. Hives, tongue swelling and throat closing were considered to be disabling, immediately life threatening and other important medical events (OMIC). The physicians assistant reported that they were not sure if the reactions was to the HPV or the Macrobid. Additional information has been requested.


VAERS ID: 268143 (history)  
Form: Version 1.0  
Age: 13.0  
Sex: Female  
Location: Alaska  
Vaccinated:2006-11-22
Onset:2006-11-30
   Days after vaccination:8
Submitted: 2006-12-03
   Days after onset:3
Entered: 2006-12-03
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 1 UN / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Areflexia, Arthropathy, Blood product transfusion, CSF glucose normal, CSF white blood cell count increased, Computerised tomogram abnormal, Cough decreased, Dysstasia, Fall, Gait disturbance, Guillain-Barre syndrome, Headache, Hypokinesia, Increased bronchial secretion, Mechanical ventilation, Motor dysfunction, Muscular weakness, Paraesthesia, Peroneal nerve palsy, Residual urine, Retching, Sinusitis, Staphylococcal infection, Urinary tract infection, Wean from ventilator
SMQs:, Rhabdomyolysis/myopathy (broad), Peripheral neuropathy (narrow), Anticholinergic syndrome (broad), Akathisia (broad), Dyskinesia (broad), Dystonia (broad), Parkinson-like events (broad), Acute central respiratory depression (broad), Guillain-Barre syndrome (narrow), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Accidents and injuries (narrow), Gastrointestinal nonspecific symptoms and therapeutic procedures (broad), Demyelination (narrow), Hypotonic-hyporesponsive episode (broad), Arthritis (broad), Respiratory failure (broad), Hypoglycaemia (broad), Infective pneumonia (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 67 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: Zyrtec prn, guaifenesin prn, tylenol prn
Current Illness: I don''t have this info
Preexisting Conditions: None that I''m aware of
Allergies:
Diagnostic Lab Data: Elevated protein in CSF; clinical symptoms suggestive of Guillain-Barre syndrome (primarily motor weakness, some altered sensation) Head CT normal except for sinusitis. Coag negative staph UTI. CSF: protein 64, glucose 57 and 7WBC. EMG on 12/5 demonstrated severe neuropathy, appeared to be a more severe form of Guillain-Barre with Miller-Fisher variant with a lot of bulbar symptoms.Bronchoscopy demonstrated H.flu left lower lobe pneumonia.
CDC Split Type:

Write-up: Pt admitted to hospital on 12/1/06 with chief complaint of ascending weakness bilaterally, upper and lower extremities. Neuro consult diagnosed Guillain-Barre syndrome. Pt received the Gardasil vaccine on 11/22/06. Resident MD asked pharmacist to write up possible ADR of Guillain-Barre from this vaccine. 02/21/2007 records received and reviewed for DOS:12/1/06-02/06/2007 DC DX:Severe form of Guillain-Barre syndrome after HPV vaccine and possible URI. Respiratory failure with prolonged mechanical ventilation and tracheostomy tube placement. Haemophilus influenzae, left lower lobe pneumonia, coag negative staph UTI. Hypertension. Tachycardia associated with dysautonomia now resolved. Presented to PCP with URI around Thanksgiving with associated sinus infection. Began having numbness and tingling in hands days of admission as well as back pain, headache and greater problems walking and began falling over. Able to wiggle her toes but with great difficulty. Pneumococcal vaccine in September/October. HPV vaccine on 11/22/06. Mother has possible MS and possible lupus. Neuro exam:Weakness of deltoid bilaterally, weakness of lower extremities with grade 4/5 weakness at hip flexor, 4/5 hip extension, 4/5 knee flexion, 4+/5 knee extension and 3+/5 plantar flexion. Deep tendon reflexes absent in all extremities even with augmentation. Plantar responses downgoing. Gait abnormal some degree of pelvic girdle weakness and foot drop bilaterally.Began IVIG. On day 2 began developing post void residuals. Vital capacity deteriorated on day 3 to 2.2 increasing difficulties with secretions as her gag and cough diminished. Able to move only jaw and eyes. Intubated and placed on fentanyl and versed. Developed HTN. Developed neuropathic pain. At discharge able to stand with assistance. Off vent on 1/26/07. Tachycardia and hypertension associated with autonomic dysfunction now resolved at discharge. Did not completely recover as of Feb 2007 when she was discharged from a rehabilitation institute. Still needing physical & speech therapy. Diagnosis, Guillain-Barre syndrome Per annual follow up information: Unfortunately, since this was a courtesy injection and pt is not our pt we have not seen this pt since and I can not say for sure if she is fully recovered-Sorry. Per 60 day follow up: Unfortunately-pat is seen by another provider & we only did the shot as a courtesy so we have not seen the pt since- Have heard through the grapevine that pt is in Rehab now & off the ventilator & standing to walk again. Per 60 day follow up: Did not completely recover as of Feb 2007 when she was discharged from a rehabilitation institute. Still needing physical & speech therapy. Diagnosis: GUILLAIN-BARRE syndrome


VAERS ID: 268286 (history)  
Form: Version 1.0  
Age: 13.0  
Sex: Female  
Location: Tennessee  
Vaccinated:2006-10-27
Onset:2006-10-27
   Days after vaccination:0
Submitted: 2006-11-30
   Days after onset:34
Entered: 2006-12-05
   Days after submission:5
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0702F / 1 UN / IM

Administered by: Other       Purchased by: Other
Symptoms: Hypersensitivity, Injection site rash, Wheezing
SMQs:, Anaphylactic reaction (broad), Angioedema (broad), Asthma/bronchospasm (broad), Eosinophilic pneumonia (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 1 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: NONE
Current Illness:
Preexisting Conditions: Penicillin allergy
Allergies:
Diagnostic Lab Data:
CDC Split Type: WAES0611USA06133

Write-up: Information has been received from a registered nurse concerning a 13 year old female with an allergy to amoxicillin who on 10/27/06 was vaccinated IM with the first dose of HPV vaccine (lot 653650/0702F). There was no concomitant medications. On 10/27/06 approx 10 minutes after the injection, the pt started to break out in a rash around the injection site. The pt then started to wheeze. The pt was given Benadryl and Depo Medrol injection. however continued to wheeze. The wheeze was then relieved by a unit of Xopenex nebulizer treatment, but after ten minutes the pt started to wheeze again. The pt went to the ER and was admitted to the hospital. The nurse reported that th event was that of a standard allergic reaction. The pt was released from the hospital the next day, however had to continue with albuterol inhaler and prednisone therapy. The pt recovered by 10/29/06 and had not experienced any further complications. The nurse reported that the pt would not be receiving any further vaccinations with HPV vaccine. The events were felt to be other important medical events (OMIC) and immediately life threatening. Additional information has been requested.


VAERS ID: 268287 (history)  
Form: Version 1.0  
Age: 21.0  
Sex: Female  
Location: Massachusetts  
Vaccinated:2006-09-25
Onset:0000-00-00
Submitted: 2006-11-30
Entered: 2006-12-05
   Days after submission:5
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0688F / UNK UN / IM

Administered by: Other       Purchased by: Other
Symptoms: Epistaxis, Headache, Platelet count decreased, Thrombocytopenia
SMQs:, Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 0 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: NONE
Current Illness:
Preexisting Conditions: Idiopathic thrombocytopenic purpura.
Allergies:
Diagnostic Lab Data: Head computed axial 9/6 unspecified, spinal tap 9/06 results unspecified. Platelet count 9/06 43000
CDC Split Type: WAES0611USA06464

Write-up: Information has been received from a physician concerning a 21 year old female with no history of drug reactions/allergies, and a history of idiopathic thrombocytopenic purpura who on 9/25/06 was vaccinated IM with HPV vaccine (Lot 653735/0688F). There was no concomitant medications. In Sept 2006, a few days after vaccination the pt experienced a headache, nose bleed and developed thrombocytopenia. The pts platelet count on an unspecified date was 43,000. The pt was hospitalized and received platelet transfusion. A CT of the head and lumbar puncture were performed, however the results were unspecified. The pt subsequently recovered on an unspecified date. The reporting physician felt that one or more of the events was an other important medical event (OMIC) and life threatening. Additional Information has been requested.


VAERS ID: 270598 (history)  
Form: Version 1.0  
Age:   
Sex: Female  
Location: Unknown  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2007-01-16
Entered: 2007-01-17
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 2 UN / IM

Administered by: Other       Purchased by: Other
Symptoms: Anaphylactic reaction, Pharyngeal oedema, Pruritus
SMQs:, Anaphylactic reaction (narrow), Angioedema (narrow), Anaphylactic/anaphylactoid shock conditions (narrow), Oropharyngeal allergic conditions (narrow), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? Yes
Recovered? Yes
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: UNK
CDC Split Type: WAES0701USA01070

Write-up: Information has been received from a physician concerning a female who was intramuscularly, vaccinated with the second dose of HPV vaccine. Subsequently the patient developed an anaphylactic reaction (swelling of the throat, itching of hands and feet). At the time of the report, it was not reported if the patient recovered. The physician determined that the patient''s anaphylactic reaction (Swelling of the throat, itching of hands and feet) was considered to be immediately life threatening, disabling and an other important medical event. Additional information has been requested.


VAERS ID: 271177 (history)  
Form: Version 1.0  
Age: 16.0  
Sex: Female  
Location: New York  
Vaccinated:2007-01-13
Onset:2007-01-13
   Days after vaccination:0
Submitted: 2007-01-24
   Days after onset:11
Entered: 2007-01-25
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0962F / 2 UN / IM

Administered by: Other       Purchased by: Other
Symptoms: Blood test normal, Chest X-ray normal, Computerised tomogram normal, Convulsion, Electrocardiogram normal, Fall, Fatigue, Loss of consciousness
SMQs:, Torsade de pointes/QT prolongation (broad), Hyperglycaemia/new onset diabetes mellitus (broad), Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Arrhythmia related investigations, signs and symptoms (broad), Convulsions (narrow), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Accidents and injuries (narrow), Hypotonic-hyporesponsive episode (broad), Generalised convulsive seizures following immunisation (narrow), Hypoglycaemia (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: chest x-ray 01/13/07 - normal, computed axial 01/13/07 - normal, electrocardiogram 01/13/07 - normal
CDC Split Type: WAES0701USA02032

Write-up: Information has been received from a health professional concerning a 16 year old female who on 11-NOV-2006 was vaccinated intramuscularly with 0.5 ml of the first dose of GARDASIL vaccine (yeast) (lot#654510/0962F) and had no difficulties with the vaccine. On 13-JAN-2007 the patient was given her second dose of GARDASIL vaccine (yeast) (lot# not provided). Within a few moments of receiving the vaccine the patient experienced a seizure, had a very brief loss of consciousness and fell to the floor. The patient was sent to the emergency room for evaluation. The patient was not admitted to the hospital. While in the emergency room she had a CT scan, chest-x-ray and unspecified blood work. The results of these tests were all negative. The patient was seen for a follow-up appointment by the physician on 16-JAN-2007. The patient reported that she was tired, however had not suffered any additional seizures. The patient was referred for a neurology consult. The physician considered the event to be life-threatening. At the time of this report the patient had not recovered from the events. Additional information has been requested.


VAERS ID: 272720 (history)  
Form: Version 1.0  
Age: 13.0  
Sex: Female  
Location: Unknown  
Vaccinated:2007-02-01
Onset:2007-02-01
   Days after vaccination:0
Submitted: 2007-02-19
   Days after onset:18
Entered: 2007-02-20
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / UNK UN / -

Administered by: Other       Purchased by: Other
Symptoms: Contusion, Haemorrhage, Rectal haemorrhage
SMQs:, Haemorrhage terms (excl laboratory terms) (narrow), Gastrointestinal haemorrhage (narrow), Accidents and injuries (narrow), Ischaemic colitis (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? Yes
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: UNK
CDC Split Type: WAES0702USA02439

Write-up: Information has been received from a health professional concerning her 13 year old female cousin with pertinent medical history and drug reactions/allergies not specified who in approximately February 2007, was vaccinated with Gardasil (Lot # not reported) 0.5 ml. Concomitant therapy was unspecified. In approximately February 2007, the patient experienced "internal bleeding throughout her body" after being vaccinated with Gardasil. The bleeding presented initially as bruising and most recently as rectal bleeding. Medical attention was sought. On an unspecified date, the patient was hospitalized. At the time of reporting, the patient had not recovered. The patient''s internal bleeding, bruising, and rectal bleeding were reported as immediately life threatening and disabling events No further information was available at the tiem of reporting. Additional information has been requested.


VAERS ID: 272942 (history)  
Form: Version 1.0  
Age:   
Sex: Female  
Location: Pennsylvania  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2007-02-22
Entered: 2007-02-23
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 1 - / -

Administered by: Other       Purchased by: Other
Symptoms: Immune system disorder
SMQs:

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, 0 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: UNK
Current Illness:
Preexisting Conditions: UNK
Allergies:
Diagnostic Lab Data: UNK
CDC Split Type: WAES0702USA02738

Write-up: Information has been received from a nurse concerning her niece (age not reported) who on an unspecified date was vaccinated with Gardasil injection. Concomitant therapy was unspecified. Subsequently, the patient experienced "immune system shut down" after receiving the vaccination. The patient had sought medical attention. On an unspecified date, the patient was hospitalized and at the time of reporting it was unknown how long the patient was hospitalized or if she was still in the hospital. It was unspecified if the patient had recovered. The nurse felt that the "immune system shut down" was considered to be immediately life-threatening. Additional information has been requested.


VAERS ID: 273099 (history)  
Form: Version 1.0  
Age: 13.0  
Sex: Female  
Location: New York  
Vaccinated:2007-02-22
Onset:2007-02-22
   Days after vaccination:0
Submitted: 2007-02-23
   Days after onset:1
Entered: 2007-02-27
   Days after submission:4
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEPA: HEP A (HAVRIX) / GLAXOSMITHKLINE BIOLOGICALS AHAVB141AA / 1 RA / IM
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 1426F / 1 RA / IM
MNQ: MENINGOCOCCAL CONJUGATE (MENACTRA) / SANOFI PASTEUR U2158AA / 1 LA / IM
TDAP: TDAP (BOOSTRIX) / GLAXOSMITHKLINE BIOLOGICALS AC52B007AA / 1 LA / IM

Administered by: Private       Purchased by: Public
Symptoms:
SMQs:

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 1 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications:
Current Illness: NONE
Preexisting Conditions: NONE
Allergies:
Diagnostic Lab Data: records received 4/5/07-CBC:66 neutrophils. 24.6 lymphocytes.
CDC Split Type:

Write-up: None Stated 03/05/07-records received from facility: seen in ED for allergic reaction to vaccines. HX of cough, wheezing and SOB few hours prior to ED visit, symptoms began 30 minutes after vaccines. Initially returned to PCP with c/o chest tightness, difficulty breathing, treated with epipen and benadryl and sent to ED. No swelling of mouth, lips or tongue. Allergies to cat (owns a cat). Uses nasonex for nasal congestion. VS P: 141, resp 20 BP 130/91. Treated with solu medol and ranitidine. Tremors, difficulty breathing. PE unremarkable. Lungs clear, no rhonchi, no wheezes. Admitted for IV steroid treatment.


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