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This is VAERS ID 488177

History of Changes from the VAERS Wayback Machine

First Appeared on 4/13/2013

VAERS ID: 488177
Age:13.0
Gender:Female
Location:Minnesota
Vaccinated:2009-08-17
Onset:0000-00-00
Submitted:2013-04-01
Entered:2013-04-01
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0216Y / 2 LA / IM

Administered by: Unknown      Purchased by: Private
Symptoms: Asthenia, Dysphagia, Dyspnoea, Eyelid ptosis, Fall, Fatigue, Myasthenia gravis, Speech disorder

Life Threatening? Yes
Died? No
Permanent Disability? Yes
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? Yes, days:     Extended hospital stay? No
Previous Vaccinations:
Other Medications: Desmopressin
Current Illness: No
Preexisting Conditions: No! Perfectly healthy.
Diagnostic Lab Data: Patient was diagnosed with Myasthenia Gravis
CDC 'Split Type':

Write-up:Began having swallowing issues, talking issues, weakness, breathing problems, droopy eyelid. The symptoms started out with her feeling tired and weak not long after the shot. By April and may she started having difficulties with swallowing and she started to fall down. I began calling doctors in may and struggled to get appointments with specialists. A pediatric neurologist didn''t diagnose anything. It was a neurologist who ordered more testing. He sent her to the facility on July 14, 2010. Patient was diagnosed with Myasthenia Gravis at the age of 14.


Changed on 6/12/2013

VAERS ID: 488177 Before After
Age:13.0
Gender:Female
Location:Minnesota
Vaccinated:2009-08-17
Onset:0000-00-00 2009-09-17
Submitted:2013-04-01
Entered:2013-04-01
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0216Y / 2 LA / IM

Administered by: Unknown      Purchased by: Private
Symptoms: Asthenia, Dysphagia, Dyspnoea, Eyelid ptosis, Fall, Fatigue, Myasthenia gravis, Speech disorder

Life Threatening? Yes
Died? No
Permanent Disability? Yes
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? Yes, days: (blank) 49     Extended hospital stay? No
Previous Vaccinations:
Other Medications: Desmopressin
Current Illness: No
Preexisting Conditions: No! Perfectly healthy.
Diagnostic Lab Data: Patient was diagnosed with Myasthenia Gravis
CDC 'Split Type':

Write-up:Began having swallowing issues, talking issues, weakness, breathing problems, droopy eyelid. The symptoms started out with her feeling tired and weak not long after the shot. By April and may she started having difficulties with swallowing and she started to fall down. I began calling doctors in may and struggled to get appointments with specialists. A pediatric neurologist didn''t diagnose anything. It was a neurologist who ordered more testing. He sent her to the facility on July 14, 2010. Patient was diagnosed with Myasthenia Gravis at the age of 14.


Changed on 9/17/2013

VAERS ID: 488177 Before After
Age:13.0
Gender:Female
Location:Minnesota
Vaccinated:2009-08-17
Onset:2009-09-17
Submitted:2013-04-01
Entered:2013-04-01
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0216Y / 2 LA / IM

Administered by: Unknown      Purchased by: Private
Symptoms: Abdominal tenderness, Anxiety, Aspiration, Asthenia, Atelectasis, Barium swallow abnormal, Biopsy lung, Biopsy lung normal, Blood culture negative, Chest pain, Chest X-ray abnormal, Choking, Cough, Culture urine negative, Diarrhoea, Diplopia, Dysarthria, Dysphagia, Dysphonia, Dyspnoea, Echocardiogram normal, Enuresis, Erythema, Eye pain, Eyelid ptosis, Fall, Fatigue, Headache, Hypotension, Migraine, Mononucleosis heterophile test negative, Muscle spasms, Myasthenia gravis, Nasal congestion, Nausea, Nuclear magnetic resonance imaging brain normal, Pain, Pain in extremity, Pain in jaw, Parasite cervical specimen test negative, Plasmapheresis, Pneumonia aspiration, Pneumothorax, Retching, Sensation of heaviness, Sinusitis, Speech disorder, Thymectomy, Visual impairment, Vomiting, Weight decreased, Antiacetylcholine receptor antibody positive, Bone density decreased, Chest tube insertion, Facial paresis, Eye pruritus, Central venous catheterisation, Pulmonary mass, Temperature intolerance, Hypoaesthesia oral, Computerised tomogram thorax abnormal, Skin test negative, Sensation of foreign body, Ultrasound scan normal, Adjustment disorder, Herpes simplex serology negative, Catheter culture positive, Immunoglobulin therapy, Streptococcus test negative, Candida test negative

Life Threatening? Yes
Died? No
Permanent Disability? Yes
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? Yes, days: 49     Extended hospital stay? No
Previous Vaccinations:
Other Medications: Desmopressin
Current Illness: No
Preexisting Conditions: No! Perfectly healthy. The following information was obtained through follow-up and/or provided by the government. PMH: tonsillectomy, adenoidectomy. Allergy: PCN.
Diagnostic Lab Data: Patient was diagnosed with Myasthenia Gravis The following information was obtained through follow-up and/or provided by the government. 4/1/2013 lab/diagnostic records received for DOS 6/30-10/25/2010. Swallow study: weakened pharyngeal contraction, overflow aspiration particularly w/ thin liquids. MRI brain: inflammatory ethmoid sinus disease, otherwise WNL. Echo, lung bx WNL. CXR: opacity of RML & RLL, pneumothorax s/p chest tube removal. CT chest: pulmonary nodules. AChR binding Ab 74.7 nmol/L (H), AChR modulating Ab 95 nmol/L (H). Striated muscle Ab, allergen testing, mono, strep (-). 4/9/2013 lab/diagnostic records received for DOS 8/13-17/2011. Blood/urine cx (-). Central line cx (+) - most likely contaminant. Echo WNL. 4/9/2
CDC 'Split Type':

Write-up:Began having swallowing issues, talking issues, weakness, breathing problems, droopy eyelid. The symptoms started out with her feeling tired and weak not long after the shot. By April and may she started having difficulties with swallowing and she started to fall down. I began calling doctors in may and struggled to get appointments with specialists. A pediatric neurologist didn''t diagnose anything. It was a neurologist who ordered more testing. He sent her to the facility on July 14, 2010. Patient was diagnosed with Myasthenia Gravis at the age of 14. The following information was obtained through follow-up and/or provided by the government. 4/1/2013 neuro consultant records received for DOS 6/30-7/14/2010. Impression: dysphagia w/ dysarthria w/o clear cause. Pt c/o 2 wk hx difficulty swallowing, mouth/tongue numbness, voice changes. Symptoms worse in evenings. Sinus infection tx''d w/ ABX 2 wks prior to symptom onset. Foods feel stuck in throat, liquids feel like they will come out nose. Pt also c/o leg weakness & pain, falling, charley horses. PE unremarkable. Sent for MRI, blood work, speech eval, EMG of legs. Condition worsened, pt aspirating on liquids (even thickened), barely able to speak, coughing & choking on saliva, increased fatigue & legs giving out, eyelids heavy. Sent for hospital admission. 4/1/2013 pedi neuro consultant records received for DOS 8/27/2010. Impression: generalized Myasthenia Gravis, stable. Pt w/ hx as above, c/o double vision, weakness (especially on rt), neck weakness, difficulty swallowing. PE: thin, weak voice, vague abdominal tenderness, some ptosis, weak facial movements, neck weakness. Pt also c/o chest pain s/p surgery - resolving. Tx''t: steroids, Mestinon adjustment. Given care & f/u instructions. 4/9/2013 PCP records received for DOS 9/17/2009-1/10/2013. Assessments: 1) headaches; 2) Myasthenia gravis. Pt followed w/ c/o nausea, vomiting, diarrhea, dry heaves, weight loss, abdominal pain, body aches, fatigue, jaw pain, nasal congestion, itchy eyes, eye pain, vision changes, chest pain, SOB, muscular weakness, migraines, heat/cold intolerance, anxiety. Symptoms treated. Aspiration pneumonia several times. Chest tubes multiple times for pneumothorax. 4/9/2013 hospital records received for DOS 7/14-19/2010, 7/31-8/10/2010. D/c Dx''s: 1) Myasthenia gravis; 2) atelectasis; 3) incidental bilateral noncalcified nodules on CT; 4) recent weight loss & at risk for malnutrition; 5) nocturnal enuresis; 6) adjustment disorder w/ anxiety. Pt hospitalized for IVIG Tx''t. C/o worsening weakness. PE: fatigability OU, ptosis w/ sustained upgaze, proximal muscle weakness, facial weakness. Tx''t: central line. Plasmapheresis not tolerated. Mestinon dose adjusted. Lung nodules noted. Abdominal pain when pt anxious. Pt d/c''d home w/ Rx''s, care, & f/u instructions. 4/9/2013 hospital records received for DOS 8/19-24/2010. D/c Dx: Myasthenia gravis. Pt unresponsive to conventional medical therapy. Tx''t: thoracoscopic thymectomy w/ lt upper lobe wedge bx, chest tube, ABX. Developed pneumothorax. Condition improved, pt d/c''d home w/ care & f/u instructions. 4/9/2013 hospital records received for DOS 6/3-12/2011, 7/18-31/2011. D/c Dx: Myasthenia exacerbation. Pt admitted multiple times for MG exacerbations. Tx''t: central line, plasmapheresis, Rituximab infusions. HOTN, pain, & fatigue during plasmapheresis. Headaches s/p plasmapheresis. D/c''d home w/ care & f/u instructions. 4/9/2013 hospital records received for DOS 8/13-17/2011, 8/27-29/2012. D/c Dx: Myasthenia exacerbation. Pt c/o pain & redness to central line site, increased weakness & difficulty chewing/swallowing, difficulty speaking, frequent coughing/gagging while eating, difficulty smiling. Symptoms typically improve over course of day. CXR concerning for lt side infiltrate. Tx''t: ABX, Rituximab. Returned c/o acute onset MG symptoms. MG well controlled w/ home Rxs, IVIG every other wk, Rituximab 4x/yr. Tx''t: ABX, IVIG. D/c''d home in stable condition w/ care & f/u instructions.


Changed on 3/14/2015

VAERS ID: 488177 Before After
Age:13.0
Gender:Female
Location:Minnesota
Vaccinated:2009-08-17
Onset:2009-09-17
Submitted:2013-04-01
Entered:2013-04-01
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0216Y / 2 LA / IM

Administered by: Unknown      Purchased by: Private
Symptoms: Abdominal tenderness, Anxiety, Aspiration, Asthenia, Atelectasis, Barium swallow abnormal, Biopsy lung, Biopsy lung normal, Blood culture negative, Chest pain, Chest X-ray abnormal, Choking, Cough, Culture urine negative, Diarrhoea, Diplopia, Dysarthria, Dysphagia, Dysphonia, Dyspnoea, Echocardiogram normal, Enuresis, Erythema, Eye pain, Eyelid ptosis, Fall, Fatigue, Headache, Hypotension, Migraine, Mononucleosis heterophile test negative, Muscle spasms, Myasthenia gravis, Nasal congestion, Nausea, Nuclear magnetic resonance imaging brain normal, Pain, Pain in extremity, Pain in jaw, Parasite cervical specimen test negative, Plasmapheresis, Pneumonia aspiration, Pneumothorax, Retching, Sensation of heaviness, Sinusitis, Speech disorder, Thymectomy, Visual impairment, Vomiting, Weight decreased, Antiacetylcholine receptor antibody positive, Bone density decreased, Chest tube insertion, Facial paresis, Eye pruritus, Central venous catheterisation, Pulmonary mass, Temperature intolerance, Hypoaesthesia oral, Computerised tomogram thorax abnormal, Skin test negative, Sensation of foreign body, Ultrasound scan normal, Adjustment disorder, Herpes simplex serology negative, Catheter culture positive, Immunoglobulin therapy, Streptococcus test negative, Candida test negative

Life Threatening? Yes
Died? No
Permanent Disability? Yes
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? Yes, days: 49     Extended hospital stay? No
Previous Vaccinations:
Other Medications: Desmopressin
Current Illness: No
Preexisting Conditions: No! Perfectly healthy. The following information was obtained through follow-up and/or provided by the government. PMH: tonsillectomy, adenoidectomy. Allergy: PCN.
Diagnostic Lab Data: Patient was diagnosed with Myasthenia Gravis The following information was obtained through follow-up and/or provided by the government. 4/1/2013 lab/diagnostic records received for DOS 6/30-10/25/2010. Swallow study: weakened pharyngeal contraction, overflow aspiration particularly w/ thin liquids. MRI brain: inflammatory ethmoid sinus disease, otherwise WNL. Echo, lung bx WNL. CXR: opacity of RML & RLL, pneumothorax s/p chest tube removal. CT chest: pulmonary nodules. AChR binding Ab 74.7 nmol/L (H), AChR modulating Ab 95 nmol/L (H). Striated muscle Ab, allergen testing, mono, strep (-). 4/9/2013 lab/diagnostic records received for DOS 8/13-17/2011. Blood/urine cx (-). Central line cx (+) - most likely contaminant. Echo WNL. 4/9/2
CDC 'Split Type':

Write-up:Began having swallowing issues, talking issues, weakness, breathing problems, droopy eyelid. The symptoms started out with her feeling tired and weak not long after the shot. By April and may she started having difficulties with swallowing and she started to fall down. I began calling doctors in may and struggled to get appointments with specialists. A pediatric neurologist didn''t diagnose anything. It was a neurologist who ordered more testing. He sent her to the facility on July 14, 2010. Patient was diagnosed with Myasthenia Gravis at the age of 14. The following information was obtained through follow-up and/or provided by the government. 4/1/2013 neuro consultant records received for DOS 6/30-7/14/2010. Impression: dysphagia w/ dysarthria w/o clear cause. Pt c/o 2 wk hx difficulty swallowing, mouth/tongue numbness, voice changes. Symptoms worse in evenings. Sinus infection tx''d w/ ABX 2 wks prior to symptom onset. Foods feel stuck in throat, liquids feel like they will come out nose. Pt also c/o leg weakness & pain, falling, charley horses. PE unremarkable. Sent for MRI, blood work, speech eval, EMG of legs. Condition worsened, pt aspirating on liquids (even thickened), barely able to speak, coughing & choking on saliva, increased fatigue & legs giving out, eyelids heavy. Sent for hospital admission. 4/1/2013 pedi neuro consultant records received for DOS 8/27/2010. Impression: generalized Myasthenia Gravis, stable. Pt w/ hx as above, c/o double vision, weakness (especially on rt), neck weakness, difficulty swallowing. PE: thin, weak voice, vague abdominal tenderness, some ptosis, weak facial movements, neck weakness. Pt also c/o chest pain s/p surgery - resolving. Tx''t: steroids, Mestinon adjustment. Given care & f/u instructions. 4/9/2013 PCP records received for DOS 9/17/2009-1/10/2013. Assessments: 1) headaches; 2) Myasthenia gravis. Pt followed w/ c/o nausea, vomiting, diarrhea, dry heaves, weight loss, abdominal pain, body aches, fatigue, jaw pain, nasal congestion, itchy eyes, eye pain, vision changes, chest pain, SOB, muscular weakness, migraines, heat/cold intolerance, anxiety. Symptoms treated. Aspiration pneumonia several times. Chest tubes multiple times for pneumothorax. 4/9/2013 hospital records received for DOS 7/14-19/2010, 7/31-8/10/2010. D/c Dx''s: 1) Myasthenia gravis; 2) atelectasis; 3) incidental bilateral noncalcified nodules on CT; 4) recent weight loss & at risk for malnutrition; 5) nocturnal enuresis; 6) adjustment disorder w/ anxiety. Pt hospitalized for IVIG Tx''t. C/o worsening weakness. PE: fatigability OU, ptosis w/ sustained upgaze, proximal muscle weakness, facial weakness. Tx''t: central line. Plasmapheresis not tolerated. Mestinon dose adjusted. Lung nodules noted. Abdominal pain when pt anxious. Pt d/c''d home w/ Rx''s, care, & f/u instructions. 4/9/2013 hospital records received for DOS 8/19-24/2010. D/c Dx: Myasthenia gravis. Pt unresponsive to conventional medical therapy. Tx''t: thoracoscopic thymectomy w/ lt upper lobe wedge bx, chest tube, ABX. Developed pneumothorax. Condition improved, pt d/c''d home w/ care & f/u instructions. 4/9/2013 hospital records received for DOS 6/3-12/2011, 7/18-31/2011. D/c Dx: Myasthenia exacerbation. Pt admitted multiple times for MG exacerbations. Tx''t: central line, plasmapheresis, Rituximab infusions. HOTN, pain, & fatigue during plasmapheresis. Headaches s/p plasmapheresis. D/c''d home w/ care & f/u instructions. 4/9/2013 hospital records received for DOS 8/13-17/2011, 8/27-29/2012. D/c Dx: Myasthenia exacerbation. Pt c/o pain & redness to central line site, increased weakness & difficulty chewing/swallowing, difficulty speaking, frequent coughing/gagging while eating, difficulty smiling. Symptoms typically improve over course of day. CXR concerning for lt side infiltrate. Tx''t: ABX, Rituximab. Returned c/o acute onset MG symptoms. MG well controlled w/ home Rxs, IVIG every other wk, Rituximab 4x/yr. Tx''t: ABX, IVIG. D/c''d home in stable condition w/ care & f/u instructions.


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