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Life Threatening? No
Write-up: This case was reported by a physician in the frame of a study and described the occurrence of ileocolic intussusception in a 9-month-old male subject who was vaccinated with ROTARIX, (GlaxoSmithKline). Previous and/or concurrent vaccination included ROTARIX; GlaxoSmithKline; oral given on 15 April 2008. On 24 June 2008 the subject received 2nd dose of ROTARIX (oral). On 21 November 2008, 150 days after vaccination with ROTARIX, the subject experienced irritability, abdominal pain and biliary vomiting. Abdominal x-ray showed a probable intussusception. Abdominal ultrasound and barium enema confirmed the diagnosis without reducing it. The same day the subject was admitted to the emergency room without clinical signs of intussusception. At physical examination only bowel was study. Laparotomy was done. ileocolic intussusception was confirmed and it was resolved by taxis without complications. On 23 November 2008 the subject was discharged fully recovered and in good clinical conditions. The subject was hospitalized for 3 days and the physician considered the events were clinically significant (or requiring intervention). The subject was treated with cefotaxime, Metamizole, midazolam, Ranitidine. The physician considered the events were possibly related to vaccination with ROTARIX.
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