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This is VAERS ID 323683

Case Details

VAERS ID: 323683 (history)  
Form: Version 1.0  
Age: 14.0  
Gender: Female  
Location: Arizona  
Vaccinated:2008-03-13
Onset:0000-00-00
Submitted: 2008-08-28
Entered: 2008-08-29
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 1978U / 1 RA / UN
MNQ: MENINGOCOCCAL CONJUGATE (MENACTRA) / SANOFI PASTEUR U2376BA / 1 LA / UN

Administered by: Other       Purchased by: Other
Symptoms: Epstein-Barr virus infection, Facial palsy, Headache, Pyrexia, VIIth nerve paralysis
SMQs:, Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious meningitis (broad), Hearing impairment (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? Yes
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 5 days
   Extended hospital stay? Yes
Previous Vaccinations:
Other Medications: MENACTRA
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: Unknown LABS: MRI revealed enhanced facial nerves c/w neuritis CSF: protein 386(H), glucose (L) WBC 60(H), lymphs 96%, macrophages 4%c/s neg. EBV (+).
CDC Split Type: WAES0808USA04178

Write-up: Information has been received from a physician concerning a 14 year old female patient who on 13-MAR-2008 was vaccinated with her first dose of GARDASIL. Concomitant therapy included MENACTRA. On 09-APR-2008, the patient experienced back pain, fever and headache. The patient was given Z-PAK. On 14-APR-2008, the patient presented at the office with complete facial paralysis and was admitted to the hospital. On 18-APR-2008, the patient was discharged. A neurologist in the hospital diagnosed her with possible Guillain-Barre and bilateral 7th cranial nerve palsy. On 24-APR-2008, the patient was seen by a physician and her adverse events were resolving but not complete. On 15-MAY-2008, the neurologist felt her symptoms were resolving and possibly not related to Guillain-Barre or GARDASIL. The neurologist diagnosed her as having Epstein-Barr meningitis. Back pain, fever, headache, facial paralysis and Epstein-Barr meningitis were considered to be disabling, immediately life-threatening and an other important medical event. Additional information has been requested. 10/3/08 Reviewed neuro medical records of 5/15/2008. FINAL DX: Epstein Barr viral meningitis with montherapy multiplex Records reveal patient experienced HA x 2 weeks in 4/2008. Developed shoulder pain, LBP, sleep disturbance & fever. Seen in ER, dx w/throat lesion & tx w/antibiotics. No response to antibiotic therapy although throat lesion did improve. Developed severe pain, facial weakness, tingling in fingertips. Hospitalized & brain MRI revealed inflammation of VII crainal nerve bilaterally. LP showed WBC (H), protein (H) & marginal glucose indicating viral meningitis. EBV IgM (H). Neuro exam on 5/15/08 revealed right facial weakness w/depressed UE reflexes. 10/31/08 Reviewed hospital medical records of 4/14-4/18/2008. FINAL DX: bilateral 7th cranial nerve palsy, possible variant of GBS triggered by acute Epstein-Barr infection. Records reveal patient experienced HA, muscle aches, fevers, strep throat, mono x approx 2 wks. Developed facial paralysis 3 days prior to admit. Exam revealed cervical & submandibular lymphadenopathy w/peritonsillar erythema. Unable to close eyes completely, could not wrinkle forehead, smile or frown. Right patella areflexia. Neuro consult done. Tx w/IVIG.


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