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This is VAERS ID 316058

Case Details

VAERS ID: 316058 (history)  
Form: Version 1.0  
Age: 21.0  
Sex: Female  
Location: Georgia  
   Days after vaccination:26
Submitted: 2008-06-12
   Days after onset:36
Entered: 2008-06-12
Vaccin­ation / Manu­facturer Lot / Dose Site / Route

Administered by: Military       Purchased by: Military
Symptoms: Blood amylase, Coagulation test, Coma, Computerised tomogram abnormal, Diarrhoea, Full blood count, Hypoaesthesia, Laboratory test, Liver function test, Mental status changes, Nausea, Urine analysis, Vomiting
SMQs:, Acute pancreatitis (broad), Peripheral neuropathy (broad), Hyperglycaemia/new onset diabetes mellitus (broad), Neuroleptic malignant syndrome (broad), Dementia (broad), Pseudomembranous colitis (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Gastrointestinal nonspecific symptoms and therapeutic procedures (narrow), Cardiomyopathy (broad), Noninfectious diarrhoea (narrow), Hypoglycaemia (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 12 days
   Extended hospital stay? Yes
Previous Vaccinations:
Other Medications: None Known
Current Illness: None Known
Preexisting Conditions: None PMH: smoker.
Diagnostic Lab Data: LABS: MRI of head & spine WNL. CT angiogram of head WNL. PET scan abnormal. Right side craniotomy for biopsy of right frontal lobe. EEGs slow but WNL. CSF: WBC 14 monos, protein 17, glucose 68, cytopathlogy revealed mostly normal lymphocytes, mostly Tcells. DNASE-B AB 680 (H). ESR 33, CRP 0.2. TTE revealed ejection fraction WNL w/mild LVH. Urine c/s (+) for e. coli. Tracheal aspirate (+) MRSA. All blood c/s neg. Renal CT scan w/lesions.
CDC Split Type:

Write-up: 21 y/o female seen in ER 13 May with C/O it hand & lt. foot numbness approximately 1 month post GARDASIL vaccine. She also C/O of nausea, vomiting and diarrhea. A heat CT demonstrated bilateral basal ganglion infarcts and a MRI showed with similar results with no acute process. She was admitted 20 May with left hemiballsmus. On 22 May her mental status declined. She received many doses of HALDOL and ATIVAN for agitation and was intubated on 28 May. She was transferred to medical center 28 may for w/u for encephalitis and has since become comatose. Symptoms: Nausea w/vomiting, Diarrhea, Nausea w/o vomiting, Numbness. 7/11/08 Reviewed hospital medical records for 6/11-6/23/2008. FINAL DX: aseptic meningo-encephalitis; choreoathetosis r/t meningo-encephalitis; paroxysmal autonomic instability w/dystonia; e. coli UTI. Records reveal pt transferred from military hospital. Military deployment 1-3/2008. On leave 5/2008 developed n/v/d, abd pain & bifrontal HA which continued to worsen. Sought medical help but no dx given. Developed left side weakness, flaccidity & several falls. Found 5/12 unable to ambulate & incontinent of urine. Taken to ER where MRI revealed possible basalganglia infarct. To ICU where subsequent MRIs were WNL. Ventilated & remains in persistent vegetative state. LPs done. PICC , trach & PEG tubes. Intermittently febrile, labile BP, asystole x2. Tx in multiple hospitals w/multiple meds including steroids, IVIG, antibiotics & antivirals. 12/11/08 Reviewed additional medical records of 5/08-7/08. FINAL DX: Records reveal patient experienced nausea/vomiting/diarrhea, dizziness & HA, left hand/foot numbness x 4-5 days. Seen in ER on 5/13 where labs were WNL but CT of brain revealed lacunar infarcts, bilateral basal ganglia & cavum verge. Numbness continued & developed involuntary jerking of LEs & difficulty walking. Admitted to MICU 6/08 w/encephalitis. Tx w/IVIG & steroids. Transferred to higher level of care & then to inpatient rehab program.

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