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Life Threatening? No
Write-up: Information has been received from a pharmacist concerning his 15 year old daughter who in September 2007 was vaccinated with Gardasil. Concomitant therapy included meningococcal vaccine (unspecified). A couple minutes after getting the vaccination, the patient suffered a grand mal seizure and fell on the ground in the office. She recovered from the grand mal seizure and was sent home. The pharmacist''s wife reported that a couple weeks after the vaccination, her daughter could not focus and would forget things. The symptoms caused problems in school, and her grades dropped. It was also reported that the patient had bad headaches, a lack of concentration, a change in personality, nausea and tasted blood in her mouth. In the last two weeks, the symptoms worsened. The patient is having daily headaches and petit mal seizures. She is going to be seen by a neurologist. At the time of this report, the symptoms persisted. The pharmacist considered his daughter''s symptoms to be disabling. Additional information has been requested. 3/24/2009 MR received from CDC. Case re-opened. Neuro consult 11/26/07 with dx: post vaccination encephalopathy. Pt may be having absence seizures. Generalized seizure after injection. Pt is intellectually impaired at this time. Per MR, pt had a tonic-clonic seizure a few minutes s/p Gardasil vax in 9/2007. Post-ictal and sore afterwards. since that time pt has had recurring staring spells, memory loss, dramatic drop in school grades (As to Fs), constant fatigue and confusion. Pt reports some visual disturbance of the L eye, H/As, occasional numbness of the hands and sphincter control issues. Currently being tx for UTI 2'' to blood in the urine. Not fully oriented on exam. PE WNL. 3/31/09 Additional records received from above neuro which include a neuropsychological eval dated 11/29-12/19/2007 with DX: Conversion D/O. Adverse reaction to HPV vaccine.
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