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This is VAERS ID 294545

Event Details

VAERS ID:294545 (history)  Vaccinated:2007-10-11
Age:67.0  Onset:2007-10-11, Days after vaccination: 0
Gender:Female  Submitted:2007-10-25, Days after onset: 14
Location:Michigan  Entered:2007-10-27, Days after submission: 2
Life Threatening? Yes
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness:
Preexisting Conditions: Unknown PMH: diverticulitis, colectomy. spinal stenosis & lumbar disk disease. Arthritis. Hypothyroid. Vit D deficiency. ALLERGIES: levaquin, sulfa & demerol.
Diagnostic Lab Data: Unknown LABS: CT & MRI head WNL. CT abdomen/pelvis. CBC WNL. TSH 0.06 (L). Ammonia 11 (L). 10/18 CSF: glucose 108, protein 255, csf culture neg. WBC 8,200, segs 67, lymphs 24. UA (+) nitrite. Urine culture (+) E. coli. EEG abnormal.
CDC 'Split Type': WAES0710USA04429
Vaccination
Manufacturer
Lot
Dose
Route
Site
PPV: PNEUMO (PNEUMOVAX)MERCK & CO. INC.0964U IMLA
VARZOS: ZOSTER (ZOSTAVAX)MERCK & CO. INC.0883U SCLA
Administered by: Other     Purchased by: Other
Symptoms: Ammonia decreased, Asthenia, Balance disorder, Blood thyroid stimulating hormone decreased, CSF culture negative, CSF glucose increased, CSF protein increased, Computerised tomogram normal, Culture urine positive, Diverticulitis, Dyspnoea, Electroencephalogram abnormal, Encephalitis, Encephalopathy, Escherichia infection, Full blood count normal, Gastrointestinal tube insertion, Injection site erythema, Injection site streaking, Injection site swelling, Intensive care, Malaise, Nuclear magnetic resonance imaging brain normal, Pain, Pyrexia, Speech disorder, Urinary tract infection, Urine analysis abnormal
SMQs:, Anaphylactic reaction (broad), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Dementia (broad), Acute central respiratory depression (broad), Psychosis and psychotic disorders (broad), Pulmonary hypertension (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (narrow), Noninfectious encephalopathy/delirium (narrow), Extravasation events (injections, infusions and implants) (broad), Gastrointestinal nonspecific inflammation (broad), Haemodynamic oedema, effusions and fluid overload (narrow), Cardiomyopathy (broad), Hypothyroidism (broad), Hyperthyroidism (broad), Vestibular disorders (broad), Chronic kidney disease (broad)
Write-up: Information has been received from a physician concerning a 67 year old female who on 11-OCT-2007 was vaccinated with a dose of Zostavax (Oka/Merck) (lot# 658207/0883U). In October 2007, the patient developed encephalitis. On 16-OCT-2007 the patient was admitted to the hospital. The patient was treated with steroids and acyclovir. The patient''s encephalitis persisted. There was no product quality complaint. The physician considered encephalitis to be immediately life-threatening and an other important medical event. Additional information has been requested. 10/30/07 Follow up initiated at request of CDC. 11/16/07 Reviewed hospital & pcp medical records which also included vax info. VAERS database updated w/same. Records reveal patient experienced trouble talking, body aches, weakness, balance difficulty, SOB, malaise & fever x 2-3 days. Admitted 10/16-10/30/2007 & then to swing bed from 10/30-11/1/07. LP done. Had seen her pcp 10/11 w/complaints of LLQ abdominal pain, diarrhea, nausea & back/left leg pain. Started on oral antibiotics at that time for diverticulitis & received zoster & pneumo vax that day. On 10/15 left arm very red & swollen w/red streaking by phone & instructed to apply ice.Apparently had word retrieval difficulty beginning 2 days s/p vax. Neuro consult. Tx w/IV antibiotics & antiviral. Tx w/steroids & antiseizure meds & transferred to ICU. PICC & feeding tube inserted. FINAL DX: Encephalopathy; UTI.

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