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This is VAERS ID 292001

Case Details

VAERS ID: 292001 (history)  
Form: Version 1.0  
Age: 15.0  
Sex: Female  
Location: Tennessee  
Vaccinated:2007-09-24
Onset:2007-09-26
   Days after vaccination:2
Submitted: 2007-10-03
   Days after onset:7
Entered: 2007-10-03
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0927U / 2 RA / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Abasia, Blood glucose normal, CSF culture negative, Dysaesthesia, Grip strength decreased, Lumbar puncture normal, Myelitis, Myelitis transverse, Protein total normal, Radiculitis, Somatosensory evoked potentials, Visual evoked potentials normal
SMQs:, Peripheral neuropathy (broad), Anticholinergic syndrome (broad), Dystonia (broad), Guillain-Barre syndrome (broad), Demyelination (narrow)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 20 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: Claritin OTC PRN for allergy symptoms
Current Illness: None
Preexisting Conditions:
Allergies:
Diagnostic Lab Data: MRI spine revealed myelitis of the lower cervical and upper thoracic spinal cord and radiculitis of the cauda equina. Lumbar puncture CSF sample shows no WBC, normal protein and glucose, no evidence of viral or bacterial infection. Somatosensory evoked potential and visual evoked potential tests revealed no abnormalities. records received 11/13/07- ESR 8, CRP less than 0.3. MRI brain and spinal cord showed myelitis involving anterior aspect of lower cervical and upper thoracic spinal column from C6 to T1 and radiculitis of cauda equina. CSF glucose 43, protein 40, 0 WBC and 10 RBC. CSF culture negative and normal IgG index. Infectious disease titers were normal. Sensory evoked potentials normal. . Neurogenic bladder. Swallowing study mild dysphagia. Urine culture trace leukocyte esterase and 7 RBC with 1+ bacteria, E. coli .
CDC Split Type:

Write-up: 2 days after 2nd dose of Gardasil, patient developed dysesthesia in arm and decrease in grip strength, leg weakness, and difficulty voiding urine. Progressed to inability to ambulate within 5 hours. Patient admitted to Medical Center. MRI revealed inflammation around spinal cord consistent with transverse myelitis vs. Guillain Barre syndrome. Clinical physical exam supported diagnosis of Transverse Myelitis. Patient treated with IV Methylprednisolone 250mg q6hr x 5 days and subsequent oral steroid taper. Over course of hospitalization, currently 7 days in duration and continuing, patient has regained some upper extremity strength and improvement in sensory symptoms. Minimal lower extremity strength recovery at this point. Throughout course of hospitalization, patient has required bladder catheterization due to inability to void urine.11/13/07-records received for DOS 9/26-10/17/07-DC DX: Transverse myelitis. Urinary tract infection (UTI). Presented to ED with 24 hour history of progressive weakness and numbness. Unable to walk. Received Gardasil 2 dys prior to symptoms and tick bite 2 weeks prior to admission. She was also on a camping trip 5 days prior to admission. PE: weak grip strength, wrist flexors and extensors normal. Right leg proximal flexor strength 2/6 and left leg strength 0/5. Distal right leg strength 0/5. Subjective numbness at T4 and below. Reflexes 1+ bilaterally in upper and lower extremities. No dysarthria. High dose steroid treatment. PlasmapheresisTransferred to rehab facility


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