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Life Threatening? No
Write-up: ved-Information has been received from a physician concerning a female who on 15-FEB-2007 was vaccinated IM with a 0.5 ml dose of Gardasil (lot # 653736/0868F). On 09-MAY-2007 the patient developed weakness and paresthesia of the upper and lower extremities. The patient was hospitalized from 09-MAY-2007 to 14-MAY-2007. The diagnosis was determined to be transverse myelitis. Details of the hospitalization and treatment were not available. The physician reported that the patient had required additional hospitalization but the details were not available. At the time of the report, the patient''s transverse myelitis persisted. Additional information has been requested. 8/29/08-from CDC-19 y/o female who received the vaccine on 2/15/07, chart indicates she refused second dose because of symptoms after first dose (although not clear), on 5/17/07 she was admitted for leg weakness/numbness. The working diagnosis was TM although occasional back spasms had them consider seizure disorder as well. She experienced her nadir of no sensation to chest level and inability to walk. At one point ONM was also considered though unclear. After which she also developed seizure disorder. Final dx (thusfar): TM and MS*. She seemed to have improved in general. 10/3/08 Reviewed hospital medical records of 5/9-5/14/2007. FINAL DX: transverse myelitis w/left sided weakness (neuro suggested Devic''s disease/neuromyelitis optica); back arching spasms; questionable seizure disorder Records reveal patient experienced left side weakness & paresthesias x 1 day. Neuro consult done & exam abnormal. Tx w/high dose steroids x 5 days w/o improvement. Transferred to higher level of care. 10/15/08-records received for DOS 5/14-5/17/08-DC DX:transverse myelitis. One week of progressive left-sided weakness and numbness. Left sided weakness.
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