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This is VAERS ID 281096

Case Details

VAERS ID: 281096 (history)  
Age: 21.0  
Gender: Female  
Location: New York  
Vaccinated:2007-01-05
Onset:2007-02-15
   Days after vaccination:41
Submitted: 2007-06-08
   Days after onset:112
Entered: 2007-06-11
   Days after submission:3
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 1424F / 0 GM / IM

Administered by: Other       Purchased by: Other
Symptoms: Biopsy, Epistaxis, Henoch-Schonlein purpura, Leukocytoclastic vasculitis, Parvovirus infection, Pharyngitis streptococcal, Purpura
SMQs:, Agranulocytosis (broad), Haemorrhage terms (excl laboratory terms) (narrow), Oropharyngeal infections (narrow), Vasculitis (narrow), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? Yes
ER or Doctor Visit? Yes
Hospitalized? No
Previous Vaccinations:
Other Medications: hormonal contraceptives, prednisone
Current Illness:
Preexisting Conditions: Unknown
Diagnostic Lab Data: Sinus probe 02/28/07 - diagnosed with leukocytoclastic vasculitis records received 6/21/07-Labs: UA unremarkable. Borderline elevation of tranaminases. Basic metabolic and liver panel normal. Proteinase 3 antibody normal. Sjogren''s SSA and SSB negative. CCP antibody negative. C-reactive protein 0.6. Parvovirus D 19 antibody elevated at 5.4. IgG, IgM negative. Cryoglobulins negative. ASO titer negative.
CDC Split Type: WAES0706USA00031

Write-up: Information has been received from a physician concerning a 22 year old female with no pertinent medical history who on 05-JAN-2007 was vaccinated with a 0.5 ml dose of Gardasil. Concomitant therapy included penicillin, prednisone and hormonal contraceptives (unspecified). On approximately 15-FEB-2007 the patient experienced strep throat. On 21-FEB-2007 the patient sought medical treatment for rash/purpura and nose bleeds. On 28-FEB-2007 the patient had a sinus biopsy and was diagnosed with leukocytoclastic vasculitis. It was determined that the patient had been exposed to parvovirus. The patient was referred to an infectious disease physician who was "ruling out" the parvovirus. At the time of the report, the results of the parvovirus are unknown. After seeing several specialist, the patient was diagnosed with Henoch-Schonlein purpura. At the time of the report, the patient had not recovered. Upon internal review, Henoch-Schonlein purpura was considered to be an other important medical event. Additional information has been requested. 6/21/07-records received for DOS 2/27-5/17/07-office visits. Presented on 2/27/07 with complaint of generalized maculopapular rash. Ecchymosis around ankles pruritic. Some resolving areas on thighs and trunk and shoulders. Started superiorly and moved inferiorly. Likely viral exanthem. Seen on 3/8/07-rash continues, assessment:leukocytoclastic vasculitis confirmed with biopsy. Seen on 3/29/07-continues to have intermittent episodes of joing swelling and stiffness, no rash at present. CT scan sinuses negative. Recent infectious history included cold in late December, on a cruise in January and developed a sore throat. HPV vaccine early January. Patient had a pet hedgehog and a python. Visit on 5/17/07-vasculitis substanitally improved.


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