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Administered by: Unknown Purchased by: Unknown
Life Threatening? No
Write-up: Information was received from a health professional concerning an 18 month old male who on 02/21/01, in the afternoon, was vaccinated with the MMRII. On 02/23/01, at 3 AM he was found in his bed "having a fit" with a temp of 40 degrees C. He was admitted to the hospital where he deteriorated rapidly. At 7:20 AM he was transferred to the pediatric ICU at another hospital. During his transfer, the child deteriorated and was described as "flat" and essentially brain dead on arrival. The anaesthetist suspected the patient may have "coned" (coning: axial displacement of the cerebellar tonsils through the foramen magnum) at that point. He was resuscitated by treatment with inotropes, antibiotics and ventilation. He had overwhelming sepsis with DIC. He was ventilated from 02/24/01 in the AM. On 02/25/01 the ventilator was switched off and the patient died. The cause of death was bacterial sepsis and disseminated intravascular coagulopathy. A post mortem was being conducted on 02/26/01. This information was received by Aventis Pasteur MSD manufacturer # UK011318. On F/U, the post mortem conducted on 2/26/01 revealed large swollen liver, clear meninges and a swollen brain. The cause of death was established as sepsis and a microscopic exam of the lung showed a 2 day old bronchopneumonic condition. No organism has yet been identified. It was reported that the family history is significant for a similar episode in sibling (did not report if related to a certain vaccination). The mother had 5 pregnancies, of which only 2 children remain. One was a stillbirth at term. One was a 4.5 year old child who died during a "fit" of a very rare degenerative brain condition (Otoharan syndrome). This is an amended report. The batch number HK45610 has been added to the narrative.
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