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Found 928 cases where Symptom is Idiopathic t hrombocytopenic purpura or Thrombocytopenia or Th rombocytopenic purpura and Vaccination Date on/after '2006-06-01'

Case Details

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VAERS ID: 319789 (history)  
Age: 22.0  
Gender: Female  
Location: Louisiana  
Vaccinated:2007-07-25
Onset:0000-00-00
Submitted: 2008-07-15
Entered: 2008-07-17
   Days after submission:2
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0515U / 1 UN / UN

Administered by: Other       Purchased by: Other
Symptoms: Blood test, Drug exposure during pregnancy, Pregnancy test negative, Thrombocytopenia, Ultrasound scan normal, Vaginal infection
SMQs:, Haematopoietic thrombocytopenia (narrow), Systemic lupus erythematosus (broad), Pregnancy, labour and delivery complications and risk factors (excl abortions and stillbirth) (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? Yes
ER or Doctor Visit? Yes
Hospitalized? No
Previous Vaccinations:
Other Medications: PREMESIS RX; UNISOM (DOXYLAMINE SUCCINATE)
Current Illness: Pregnancy NOS (LMP = 7/30/2007); Cervical dysplasia; Hyperemesis
Preexisting Conditions:
Diagnostic Lab Data: diagnostic laboratory - results not reported; ultrasound, 09/20/07 - IUP at 7.2 weeks; serum alpha-fetoprotein, 12/07/07 - negative; Apgar score, 04/22/08 - 8/9
CDC Split Type: WAES0709USA01334

Write-up: Initial and follow-up information has been received through the Merck Pregnancy registry via a healthcare professional and a physician concerning a 22 year old white female with mild cervical dysplasia and a history of 2 previous pregnancies with full term delivered (January 2002 and August 2004) who on 25-MAY-2007 was vaccinated with the first dose of GARDASIL (lot #653736/0014U). On 25-JUL-2007, the patient was vaccinated with the second dose of GARDASIL (Lot #657872/0515U). Concomitant medications included UNISOM and PREMESIS. On approximately 25-MAY-2007, the patient developed vaginitis and on 25-MAY-2007 was placed on therapy with TINDAMAX. It was reported on 10-SEP-2007, the patient was 6 weeks pregnant. On 20-SEP-2007, ultrasound revealed intra-uterine pregnancy at 7.2 weeks. The patient last menstrual period (LMP) was of 30-JUL-2007 and estimated of delivery was 05-MAY-2008. The patient underwent unspecified blood work (results not reported). Unspecified medial attention was sought. On an unspecified date, the patient developed thrombocytopenia. On 22-APR-2008, 38.1 weeks from LMP, the patient delivered a healthy male infant. Weight was 7 pounds 8 ounces, head circumference was 13 5/8 inches and length was 20.5 inches. Apgar score was 8/9. On 20-MAY, the patient was vaccinated with a third dose of GARDASIL (lot # 660387/1967U). Other medications used this pregnancy included PRIMACARE ONE. Additional information has been requested.


VAERS ID: 320992 (history)  
Age: 17.0  
Gender: Female  
Location: Nevada  
Vaccinated:2008-07-07
Onset:2008-07-17
   Days after vaccination:10
Submitted: 2008-07-31
   Days after onset:14
Entered: 2008-07-31
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEPA: HEP A (HAVRIX) / GLAXOSMITHKLINE BIOLOGICALS AHAVB280AA / - UN / IM
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 1267U / - UN / IM
MNQ: MENINGOCOCCAL CONJUGATE (MENACTRA) / SANOFI PASTEUR U2548AA / - UN / IM
TDAP: TDAP (BOOSTRIX) / GLAXOSMITHKLINE BIOLOGICALS AC52B021CB / - UN / IM

Administered by: Private       Purchased by: Unknown
Symptoms: Contusion, Differential white blood cell count normal, Idiopathic thrombocytopenic purpura, Platelet count decreased
SMQs:, Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Accidents and injuries (narrow), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness: None
Preexisting Conditions: DUB; Acne; started on ortho tri-cyclen 7/7/08. PMH: migraines.
Diagnostic Lab Data: Differential normal. 9/15/08-records received-Platelets ranged from 16,000 to 166,000 on 8/9/08. 9/22/08-records received-Von Wilebrand''s panel negative.
CDC Split Type:

Write-up: Increased and very large bruises noted by patient - worse than her usual "easy bruising" around 1 1/2 week after shots. CBC showed ITP. Platelets = 22 on 7/21/08. Immunizations given 7/7/08. 9/15/08-records received-Outpatient infusion documentation received-treated with WINRho.9/22/08-records received for DOS 7/7/08-received vaccination. Regular periods. Begin BCP ortho-tri-cyclen.. Period 5-7 days heavy with clots. 7/28/08-Increased bruising and very large ones from minor trauma today. Symptoms began about 1 1/2 week ago with larger and more bruises. Feels fine. After vaccination on 7/7/08 felt little under the weather for 2 days.


VAERS ID: 321142 (history)  
Age: 21.0  
Gender: Unknown  
Location: Unknown  
Vaccinated:2008-04-15
Onset:2008-04-15
   Days after vaccination:0
Submitted: 2008-07-31
   Days after onset:107
Entered: 2008-08-01
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
SMALL: SMALLPOX (NO BRAND NAME) / UNKNOWN MANUFACTURER - / - UN / ID
TYP: TYPHOID VI POLYSACCHARIDE (NO BRAND NAME) / UNKNOWN MANUFACTURER A0522 / - UN / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Anaemia, Aplastic anaemia, Aspiration bone marrow, Basophil count normal, Biopsy bone marrow abnormal, Bone marrow failure, Ecchymosis, Eosinophil count normal, Granulocyte count decreased, Haematocrit normal, Haemoglobin normal, Lymphocyte count decreased, Mean cell haemoglobin concentration, Mean cell haemoglobin increased, Mean cell volume abnormal, Monocyte count decreased, Neutrophil count decreased, Pancytopenia, Platelet count decreased, Red blood cell count decreased, Red blood cell count increased, Thrombocytopenia, White blood cell count decreased
SMQs:, Agranulocytosis (narrow), Haematopoietic cytopenias affecting more than one type of blood cell (narrow), Haematopoietic erythropenia (narrow), Haematopoietic leukopenia (narrow), Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Haemorrhage laboratory terms (broad), Systemic lupus erythematosus (narrow), Malignancy related therapeutic and diagnostic procedures (narrow), Malignant lymphomas (broad), Myelodysplastic syndrome (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness:
Preexisting Conditions:
Diagnostic Lab Data: bone marrow biopsy: The peripheral smear shows a pancytopenia with a particularly marked reduction in platelets. The erythrocytes show an increased MCV and MCH, but the MCHC and RDW are within normal limits. Lymphocytes, monocytes, and granulocytes are reduced in number, but no abnormal or dyspoeitic forms are identified. No giant platelets are identified. The bone marrow aspirate is extremely dilute with no spicules present and is noncontributory. Similarly, the clot section and touch preps yield no valuable information. Evaluation of hematopoiesis is performed on the core which shows markedly reduced cellularity (15%), particularly given the patient''s age. The myeloid-to-erythroid ratio is estimated to be 3:1. All cell lines appea
CDC Split Type:

Write-up: SM was participating in SPV protocol and was noted to have a low plt ct prior to receipt or SPV on 4/15/08. Subsequent blood draws indicated thrombocytopenia and anemia as well. Symptoms: Ecchymosis.


VAERS ID: 323333 (history)  
Age: 5.0  
Gender: Female  
Location: Illinois  
Vaccinated:2008-07-17
Onset:2008-08-05
   Days after vaccination:19
Submitted: 2008-08-26
   Days after onset:21
Entered: 2008-08-26
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMR: MEASLES + MUMPS + RUBELLA (NO BRAND NAME) / UNKNOWN MANUFACTURER 0528X / - UN / UN
VARCEL: VARICELLA (NO BRAND NAME) / UNKNOWN MANUFACTURER 0346X / - UN / UN

Administered by: Unknown       Purchased by: Unknown
Symptoms: Autoimmune thrombocytopenia, Contusion, Idiopathic thrombocytopenic purpura
SMQs:, Haemorrhage terms (excl laboratory terms) (narrow), Accidents and injuries (narrow), Hypersensitivity (narrow)

Life Threatening? Yes
Died? No
Permanent Disability? No
Recovered? Yes
ER or Doctor Visit? Yes
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness: none
Preexisting Conditions: Autism Spectrum Disorder 12/11/08-records received-PMH: possible autistic spectrum disorder.
Diagnostic Lab Data: Diagnosed with Immune thrombocytopenic Purpura (ITP)Hemotologist diagnosed as a result of varicella vaccine. 12/11/08-records received-Platelet count 7000.
CDC Split Type:

Write-up: Severe bruising over entire body. Requires multiple weekly blood tests for several months to monitor platlet count. 12/11/08-records received for DOS 8/19/08-seen for 11 day history of easy bruising and rash classic for petechiae. Impression:classic childhood auto-immune thrombocytopenic purpura (AITP or ITP) likely trigger 4 weeks prior is VZV vaccine.


VAERS ID: 325170 (history)  
Age:   
Gender: Female  
Location: Indiana  
Vaccinated:2007-10-08
Onset:0000-00-00
Submitted: 2008-09-09
Entered: 2008-09-16
   Days after submission:7
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0388U / 0 UN / UN

Administered by: Other       Purchased by: Other
Symptoms: Idiopathic thrombocytopenic purpura, Injection site pain
SMQs:, Haemorrhage terms (excl laboratory terms) (narrow), Extravasation events (injections, infusions and implants) (broad), Hypersensitivity (narrow)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness:
Preexisting Conditions: Unknown
Diagnostic Lab Data: Unknown
CDC Split Type: WAES0808USA04883

Write-up: Initial and follow-up information has been received from a physician concerning a female patient who on 08-OCT-2007, was vaccinated with her first dose of GARDASIL (Lot # 657622/0388U). On 07-DEC-2007, was vaccinated with her second dose of GARDASIL (Lot # 659435/1265U). On 23-JUN-2008, was vaccinated with her third dose of GARDASIL (Lot # 660393/0067X). After receiving the vaccine "the patient experienced numbness at injection site. The physician stated that she may have thrombocytopenia, she required platelets." The patient sought unspecified medical attention. In follow-up, the nurse reported that the patient had a concurrent condition of Idiopathic thrombocytopenic purpura (ITP). The nurse stated that the patient''s mother inquired if the GARDASIL vaccinations had anything to do with the problems her daughter was experiencing with ITP. The nurse stated that the patient made a general statement that the injection was painful and the patient did not complain of injection numbness. Upon internal review, thrombocytopenia was determined to be an Other Important Medical Event. No further information is available. This is follow-up to report(s) on 09/09/2008: Information has been received from a physician concerning a female patient who was vaccinated with GARDASIL. After receiving the vaccine "the patient experienced numbness at injection site. The physician stated that she may have thrombocytopenia, she required platelets." The patient sought unspecified medical attention. Additional information has been requested.


VAERS ID: 325524 (history)  
Age: 14.0  
Gender: Female  
Location: Louisiana  
Vaccinated:2008-07-22
Onset:2008-07-22
   Days after vaccination:0
Submitted: 2008-08-14
   Days after onset:23
Entered: 2008-08-18
   Days after submission:4
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 1 UN / IM

Administered by: Other       Purchased by: Other
Symptoms: Platelet count decreased, Thrombocytopenia
SMQs:, Haematopoietic thrombocytopenia (narrow), Systemic lupus erythematosus (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? No
Previous Vaccinations:
Other Medications: None
Current Illness: Skin lesion
Preexisting Conditions:
Diagnostic Lab Data: platelet count - 07/22/08 - 40.00, platelet count - 07/24/08 - 42.00
CDC Split Type: WAES0807USA05111

Write-up: Information has been received from a physician concerning a 14 year old female patient who on 20-MAY-2008, was vaccinated with the first dose of GARDASIL vaccine (yeast) and the second dose of GARDASIL vaccine (yeast) was given on 22-JUL-2008. The patient had a lesion removed from her scalp (the lesion was present prior to starting of the HPV vaccine series). When the plastic surgeon requested to have additional margins of the lesion area of the scalp removed he performed a complete blood count on 22-JUL-2008 that showed a platelet count of 40.000. A diagnosis of thrombocytopenia was given. A repeat complete blood count was performed on 24-JUL-2008, and that showed a platelet count of 42.000. The physician mentioned that he spoke with the pathologist performing the complete blood count/manual smear review and was told that the smear was normal. The patient''s thrombocytopenia persisted. Additional information has been requested.


VAERS ID: 326106 (history)  
Age: 9.0  
Gender: Male  
Location: New York  
Vaccinated:2008-09-09
Onset:2008-09-18
   Days after vaccination:9
Submitted: 2008-09-22
   Days after onset:4
Entered: 2008-09-25
   Days after submission:3
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
FLU3: INFLUENZA (SEASONAL) (FLUZONE) / SANOFI PASTEUR U2786AA / 5 LL / UN

Administered by: Private       Purchased by: Private
Symptoms: Activated partial thromboplastin time normal, Blood culture negative, Contusion, Granulocyte count decreased, Haemoglobin normal, Idiopathic thrombocytopenic purpura, Lice infestation, Lymphocyte percentage, Monocyte percentage, Petechiae, Platelet count decreased, Prothrombin time normal, Rash, White blood cell count normal
SMQs:, Anaphylactic reaction (broad), Haematopoietic leukopenia (narrow), Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Accidents and injuries (narrow), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 2 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications:
Current Illness: None
Preexisting Conditions: None. PMH: Asthma, recent lice, impetigo. NKDA
Diagnostic Lab Data: WBC, 7.2; HgB, 14; Platelet count, 12; 40 L; 8 M; 51 GR; nl PT/PTT; (-) blood cx . Labs and Diagnostics: Platelet counts 12K, 16K, up to 35K after WinRho. Coags WNL. Alk Phos 149. ANA (-).
CDC Split Type:

Write-up: FLUZONE given 9/9/08. Had lice 9/15/08. Treated with NIX and homeopathic oils. Developed rash seen 9/19 (+) petechiae, bruising, platelet ct = 12. Admit Monday to hospital. Given Win-Rho suspect ITP. 11/26/08 MR received for DOS 9/19-20/2008 with DX: ITP. Pt presented with 1 wk hx of bruising with more recent addition of petechiae and purpura. Platelet count of 12K at PMD''s office. Admitted for WinRho tx of thrombocytopenia. Platelet count up to 35K prior to d/c. Will f/u as outpt.


VAERS ID: 326397 (history)  
Age: 7.0  
Gender: Female  
Location: Maryland  
Vaccinated:2008-07-31
Onset:2008-09-10
   Days after vaccination:41
Submitted: 2008-09-18
   Days after onset:8
Entered: 2008-09-29
   Days after submission:11
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEPA: HEP A (HAVRIX) / GLAXOSMITHKLINE BIOLOGICALS AHAVB284 / 1 LA / IM

Administered by: Private       Purchased by: Private
Symptoms: Idiopathic thrombocytopenic purpura, Pyrexia
SMQs:, Haemorrhage terms (excl laboratory terms) (narrow), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? Yes, 4 days
   Extended hospital stay? No
Previous Vaccinations: Fever~Hep A (no brand name)~1~7.00~Patient
Other Medications: No
Current Illness: No
Preexisting Conditions: Thrombocytopenia secondary; granuloma annulare to arms; cutaneous lupus PMH: ITP, 11/2007. Anemia. Received IVIG 7&8/2008 for recurrent ITP. Pityriasis (resolved), granuloma annulare x 4 years, recurrent sinus infections, heart murmur
Diagnostic Lab Data: Not available at present LABS: ESR 101(H). ANA neg. AST 244(H), ALT 71(H), alk phos 86 (L). WBC 3.7 (L), H/H 9.3/30.1(L), plts 22K, Cardiolipin IgM 15(H). Blood c/s neg. CT sinuses, CXR, abdominal US WNL. Calf skin lesion biopsy revealed superficial & deep perivascular lymphohistiocytic inflammation w/rare apoptotic kertinocytes c/w viral exanthem, insect bite reaction & drug reaction. Bone marrow biopsy revealed moderatly hypercellular marrow w/trilineage hematopoiesis c/w hematophagocytic syndrome. UA w/2+ protein
CDC Split Type:

Write-up: C/O fever and ITP x5-6 days - Mom went to ped E.D. 9/15/08 at 10 AM for evaluation - then admitted to inpatient for further mgmt by ped. hematology. Currently being treated with supportive therapy and empiric IV antibiotic therapy - awaiting culture results (see note) and bone marrow pathology. 10/1/08 Reviewed hospital medical records of 9/15-9/18/2008. FINAL DX: atypical idiopathic thrombocytopenic, extension of chronic skin condition Records reveal patient experienced fever x 10 days, nasal congestion, mild periumbilical pain, fatigue, thigh myalgias, bruising/petechia, 4-hour nosebleed, gum bleeding x 1 week. Tx w/IVF, IV antibiotics, steroids. Derm & Rheum consults done. Derm felt rash probably viral exanthem. Rheum felt probable evolving SLE. Improved & d/c to home on tapering steroids to be f/u in heme/onc clinic.


VAERS ID: 329847 (history)  
Age: 7.0  
Gender: Female  
Location: Illinois  
Vaccinated:2008-08-25
Onset:2008-09-21
   Days after vaccination:27
Submitted: 2008-10-23
   Days after onset:32
Entered: 2008-10-23
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
FLUN3: INFLUENZA (SEASONAL) (FLUMIST) / MEDIMMUNE VACCINES, INC. 500543P / - - / IN

Administered by: Private       Purchased by: Private
Symptoms: Idiopathic thrombocytopenic purpura, Platelet count decreased
SMQs:, Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? No
Hospitalized? Yes, 2 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications:
Current Illness:
Preexisting Conditions: 11/12/08-records received-PMH:35 week twin, required 10-12 days intubation, jaundice.
Diagnostic Lab Data: Still undergoing RX with IVIG to increase plt count (between 4.000-26.000 since then) 11/12/08-record received- Platelets <5, WBC 3.52, hematocrit 33, neutrophils absolute 1.228.
CDC Split Type:

Write-up: Received FLUMIST on 08/25/2008. On 9/21/2008 was admitted to CMH with diagnosis ITP. Was told by specialists ITP caused by virus; per mom, only known before ITP was live FLUMIST. 11/12/08-records received for DOS 9/21-9/23/08-DC DX: ITP. Presented with petechial rash on shins bilaterally. Rash non=pruritic. Bruising later same day. Evening of admission developed raised erythematous lesion on tongue and corners of mouth. Treated with IVIG. Follow-up: As of 1/7/09 was to followup in hospital hematology clinic in 2-3 months. If counts normal then, would discharge from hematology as resolved. If counts still abnormal followup CBC''s in office / clinic until resolved. Last platelets 153K (NL 150 - 450).


VAERS ID: 331918 (history)  
Age: 1.55  
Gender: Male  
Location: Florida  
Vaccinated:2008-10-08
Onset:2008-10-25
   Days after vaccination:17
Submitted: 2008-11-10
   Days after onset:16
Entered: 2008-11-10
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
DTAP: DTAP (INFANRIX) / GLAXOSMITHKLINE BIOLOGICALS AC14B084AA / 3 LL / IM
HEP: HEP B (RECOMBIVAX HB) / MERCK & CO. INC. 1106F / 2 RL / IM
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 0664Y / 0 RL / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: Idiopathic thrombocytopenic purpura, Platelet count decreased
SMQs:, Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 2 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: none
Current Illness: none
Preexisting Conditions: Repair of small urethral opening done in foreign country at 2 months of age. Also in foreign country, hospitalized for one week at 6 months of age for "fever and breathing problems." PMH: Came to country approx 2 mo prior.
Diagnostic Lab Data: Platelets 14,000 10/25/08. Recovered to 151,000 on 10/29/08
CDC Split Type:

Write-up: Patient developed ITP on 10/25/08 with a platelet count of 14,000. 12/2/08 Reviewed hospital medical records of 10/25-10/27/2008. FINAL DX: Idiopathic thrombocytopenic purpura Records reveal patient experienced extensive bruising & petechiae, marked auricular & inguinal lymphadenopathy x 1 day. Tx w/IVIG


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