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Found 963 cases where Symptom is Idiopathic t hrombocytopenic purpura or Thrombocytopenia or Th rombocytopenic purpura and Vaccination Date on/after '2006-06-01'

Case Details

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VAERS ID: 308021 (history)  
Form: Version 1.0  
Age: 21.0  
Gender: Female  
Location: Ohio  
Vaccinated:2007-01-01
Onset:2007-03-01
   Days after vaccination:59
Submitted: 2008-03-07
   Days after onset:372
Entered: 2008-03-19
   Days after submission:11
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEP: HEP B (RECOMBIVAX HB) / MERCK & CO. INC. - / 2 UN / UN

Administered by: Private       Purchased by: Other
Symptoms: Platelet count decreased, Platelet transfusion, Thrombocytopenia
SMQs:, Haematopoietic thrombocytopenia (narrow), Systemic lupus erythematosus (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 0 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: FIORICET TABLETS; folic acid; prednisone
Current Illness: Allergic reaction to antibiotics
Preexisting Conditions:
Allergies:
Diagnostic Lab Data: Platelet count 01/??/07 20,000 (value)
CDC Split Type: WAES0703USA03729

Write-up: Information has been received from a registered nurse (RN) concerning a female with an allergy to erythromycin who was vaccinated with a second dose of Recombivax HB at a hospital in January of 2007. Concomitant therapy included folic acid, prednisone and FIORICET TABLETS. Subsequently, the patient experienced thrombocytopenia. It was reported that the patient has received two doses of Recombivax HB so far but it was unknown if the thrombocytopenia occurred with dose 1 or dose 2 or with both. Unspecified medical attention was sought, "bloodwork showed that patient''s levels went down to 20,000". The patient was treated with steroids and her thrombocytopenia had only slightly improved. It was reported that the patient will not be given dose 3. As of 23-Mar-2007, the patient''s status was unknown. No product quality complaint was involved. Follow-up information was received on 07-JUN-2007 indicating that the patient was hospitalized as a result of thrombocytopenia. A platelet transfusion was performed and the patient was treated with IVIG. At the time of this report the patient was "still being treated". It was indicated that the patient''s thrombocytopenia occurred in March 2007 after receiving his second dose of Recombivax HB in January 2007. Additional information has been requested.


VAERS ID: 308332 (history)  
Form: Version 1.0  
Age: 17.0  
Gender: Female  
Location: Michigan  
Vaccinated:2007-11-29
Onset:0000-00-00
Submitted: 2008-03-26
Entered: 2008-03-27
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 2 UN / UN

Administered by: Other       Purchased by: Other
Symptoms: Blood product transfusion, Contusion, Laboratory test, Thrombocytopenia
SMQs:, Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Accidents and injuries (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 0 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: diagnostic laboratory - unknown
CDC Split Type: WAES0803USA03311

Write-up: Information has been received from a physician concerning a 17 year old female patient who on 05-OCT-2007 and 29-NOV-2007 was vaccinated with the first and second doses of GARDASIL, respectively. It was reported that post vaccination the patient complained of severe bruising on her arm and leg, without impact. It is unknown exactly where on the arm or leg bruising occurred. The patient was hospitalized and "lots of tests were performed" leading to a diagnosis of immune thrombocytopenia. The patient was treated with "Immunoglobulin Intravenous," and was discharged from the hospital. At the time of this report the patient''s outcome was unknown. No product quality complaint was involved. Immune thrombocytopenia was considered to be an other medically important event. Additional information has been requested.


VAERS ID: 309085 (history)  
Form: Version 1.0  
Age: 0.0  
Gender: Male  
Location: Wisconsin  
Vaccinated:2007-07-01
Onset:2007-07-02
   Days after vaccination:1
Submitted: 2008-01-23
   Days after onset:205
Entered: 2008-04-08
   Days after submission:75
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEP: HEP B (FOREIGN) / MERCK & CO. INC. 0608F / 1 LL / UN

Administered by: Private       Purchased by: Other
Symptoms: Ascites, Biopsy bone marrow normal, Biopsy liver normal, Biopsy skin normal, Cardiopulmonary failure, Convulsion, Death, Dyspnoea, Encephalopathy, Endotracheal intubation, General physical health deterioration, Hepatosplenomegaly, Multi-organ failure, Oxygen supplementation, Peritoneal dialysis, Platelet count decreased, Platelet transfusion, Pseudomonal sepsis, Pyrexia, Rash, Renal failure, Thrombocytopenia
SMQs:, Rhabdomyolysis/myopathy (broad), Acute renal failure (narrow), Cardiac failure (narrow), Liver related investigations, signs and symptoms (narrow), Hepatic failure, fibrosis and cirrhosis and other liver damage-related conditions (narrow), Anaphylactic reaction (narrow), Acute pancreatitis (broad), Agranulocytosis (broad), Angioedema (broad), Haematopoietic thrombocytopenia (narrow), Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (narrow), Anticholinergic syndrome (broad), Retroperitoneal fibrosis (broad), Shock-associated circulatory or cardiac conditions (excl torsade de pointes) (broad), Torsade de pointes, shock-associated conditions (broad), Hypovolaemic shock conditions (broad), Toxic-septic shock conditions (broad), Anaphylactic/anaphylactoid shock conditions (broad), Hypoglycaemic and neurogenic shock conditions (broad), Convulsions (narrow), Acute central respiratory depression (broad), Pulmonary hypertension (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (narrow), Noninfectious meningitis (broad), Haemodynamic oedema, effusions and fluid overload (narrow), Cardiomyopathy (broad), Generalised convulsive seizures following immunisation (narrow), Chronic kidney disease (narrow), Hypersensitivity (narrow), Tumour lysis syndrome (broad), Respiratory failure (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (narrow), Hypoglycaemia (broad)

Life Threatening? Yes
Birth Defect? No
Died? Yes
   Date died: 2007-08-10
   Days after onset: 39
Permanent Disability? Yes
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? Yes
Previous Vaccinations:
Other Medications:
Current Illness: None
Preexisting Conditions: None. Prenatal and PMH: Mother (+) for Gestational Diabetes. GBS (+)-treated. Mother had febrile illness/GE 10-14 days prior to delivery.
Allergies:
Diagnostic Lab Data: Lab studies showed on DOL #2 showed a normal CBC and differential. <24 hours after the vaccine, showed severe thrombocytopenia which remained low throughout his hospital course despite twice daily platelet transfusions, etc. Labs and Diagnostics: WBCs 21.5. Platelets 9000 on DOL#3 and remained low. HCT and Hgb low. Chemistry abnormal. BUN 75. LFTs abnormal. Hearing test failed. US of head (-) for intracranial hemorrhage. Abd US (+) for enlarged kidneys with increased echo texture, moderate ascites. EEG abnormal. ECG sinus tach. Chromosomal analysis WNL. Urine organic acids (+).
CDC Split Type:

Write-up: Patient was a term infant who had had an uneventful delivery. He did develop a fever in the first 24 hours of life, was treated with IV antibiotics but blood culture was negative so IV abx were stopped after 48 hours. He was monitored for several days and did well. He was scheduled for discharge and received HepB vaccine 24 hour prior to scheduled discharge. 12 hours after immunization, parents report his fevers returned and he developed a skin rash. He also had difficulty breathing requiring supplemental oxygen by nasal cannula. A few days later, he deteriorated dramatically, required endotracheal intubation and started having seizures. He then became encephalopathic and had cardiopulmonary collapse as well as multi-system organ failure. An EXTENSIVE work up was done. No infectious, endocrinologic, hematologic or neurologic cause was found. He developed massive ascites, hepatosplenomagaly and renal failure requiring peritoneal dialysis. He had skin biopsies, liver biopsies, bone marrow biopsies in addition to an exhaustive amount of blood work for common and rare disorders-all were negative. Patient eventually died at 6 weeks of age from Pseudomonal sepsis. Lab studies showed on DOL #2 showed a normal CBC and differential. <24 hours after the vaccine, showed severe thrombocytopenia which remained low throughout his hospital course despite twice daily platelet transfusions, etc. 4/11/2008 Autopsy report and Case Summary received for DOD 8/10/2007. Term infant developed fever (T=103''F), respiratory distress and irritability at 4 hrs of age. Txd with Acyclovir for presumed viral infection, viral cultures (-). Pt later developed macular rash which resolved. Pt developed fever and increasing respiratory distress ultimately requiring intubation on 7/8/07. Infant became edematous and developed thrombocytopenia and seizures. Transfered to higher level of care. Upon admission pt exibited temperature elevations, twitching, rash, throbocytopenia. Sepsis w/u (-). Pt dx: Bone marrow failure with gram-negative sepsis and renal failure. Deeply purpuric rash noted after admission. 6 wk hospital course was dominated by diffuse edema, respiratory distress, thrombocytopenia and renal failure. ID consult suspect Neonatal Onset Multisystem Inflammatory Disease (NOMID). Autopsy revealed anasarca, Pseudomonas pneumonia, multiple hemorrhagic infarcts of the spleen, hypoplastic bone marrow, cholestatic hepatopathy, and marked thymic involution. Presumed COD: Overwhemling sepsis. Contributing COD: Pancytopenia.


VAERS ID: 309900 (history)  
Form: Version 1.0  
Age: 22.0  
Gender: Male  
Location: North Carolina  
Vaccinated:2008-03-11
Onset:2008-03-21
   Days after vaccination:10
Submitted: 2008-04-17
   Days after onset:27
Entered: 2008-04-17
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEPA: HEP A (NO BRAND NAME) / UNKNOWN MANUFACTURER - / UNK UN / UN
SMALL: SMALLPOX (NO BRAND NAME) / UNKNOWN MANUFACTURER - / 1 UN / -
TYP: TYPHOID VI POLYSACCHARIDE (NO BRAND NAME) / UNKNOWN MANUFACTURER A0522 / 1 UN / UN

Administered by: Military       Purchased by: Military
Symptoms: Platelet count decreased, Thrombocytopenia
SMQs:, Haematopoietic thrombocytopenia (narrow), Systemic lupus erythematosus (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Patient was given Hepatitis A vaccine on 11 March 2008 as well.
Current Illness: None
Preexisting Conditions: No chronic medical conditions; NKDA; No birth defects. PMH: childhood hospitalization for measles & respiratory illness. Smoker & ETOH user.
Allergies:
Diagnostic Lab Data: Labs: 3/11/08; CBC: PLT 170K; WBC 8.7; HGB 13.8; HCT 41.1%; 3/17/08 CBC: PLT 129K; WBC 6.4; HGB 14.3; HCT 43%; 3/21/08 CBC: PLT 71K; WBC 7.5; HGB 14.5; HCT 43.5%; 4/15/08 CBC: PLT 137K; WBC 6.4; HGB 14.5; HCT 43.5%. LABS: Pre-vaccination plts 170K, post vaccination plts 129K with a low on 3/21/08 of 70K. Most recent plts 174K on 5/13/08.
CDC Split Type:

Write-up: 22 year old patient received ACAM2000, Typhoid, and Hepatitis A vaccines on 11 March 2008. He was found on follow-up lab testing to have developed Thrombocytopenia (last PLT 70K) after an initially normal PLT count of 170K before beginning the study. 6/24/08 Reviewed medical records of 4/15/2008. FINAL DX: thrombocytopenia Records reveal patient was in good health on day of vaccination. Had 1-2 days of mild axillary pain s/p vaccinations.


VAERS ID: 314918 (history)  
Form: Version 1.0  
Age: 15.0  
Gender: Female  
Location: Tennessee  
Vaccinated:2008-05-27
Onset:2008-05-30
   Days after vaccination:3
Submitted: 2008-05-30
   Days after onset:0
Entered: 2008-06-04
   Days after submission:5
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEPA: HEP A (HAVRIX) / GLAXOSMITHKLINE BIOLOGICALS AHAVB264CA / 1 LA / IM
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 1757U / 1 RA / IM
MNQ: MENINGOCOCCAL CONJUGATE (MENACTRA) / SANOFI PASTEUR U2406AA / 1 LA / IM

Administered by: Private       Purchased by: Private
Symptoms: Idiopathic thrombocytopenic purpura
SMQs:, Haemorrhage terms (excl laboratory terms) (narrow), Hypersensitivity (narrow)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness:
Preexisting Conditions: Dx ITP PMH: allergies PCN, cephapir
Allergies:
Diagnostic Lab Data: Dx with ITP (5-30-08) LABS: SGOT 90, SGPT 87. UA w/occult blood. LABS: Initial plts 7K (L). Final plts 75. Monospot (+).
CDC Split Type:

Write-up: Dx with ITP. 6/10/08 Reviewed PCP medical records of 5/27-6/6/08. FINAL DX: Idiopathic thrombocytopenic purpura; mononucleosis Records reveal that on day of vaccination patient experienced low grade fever, decreased appetite, nausea, hands itching x 1 day. Exam revealed excoriated area of left hand between thumb & 1st digit appearing like eczema. Returned to office 5/30 w/petechial rash all over except hands & feet & diarrhea. Referred to hematology. Tx w/IVIG. Returned to office 6/2 w/improved purpura. Returned to clinic 6/4 w/continued improvement but new erythematous exudate & enlarged tonsills & cervical lymphadenopathy. Referred to heme for additional IVIG. By 6/6 platelets & rash had improved considerably. To continue f/u in 10 days for labs. 7/4/08 Reviewed heme/onc clinic medical records of 5/30/08 FINAL DX: immune mediated type thrombocytopenia. Records reveal patient experienced fever, achiness, nausea & diarrhea approx 8 days prior to onset of symptoms which resolved; gum bleeding & lower extremity petecchial rash on day of consult. Seen by PCP & referred emergently to heme/onc. Tx w/IVIG while in clinic & serial labs followed.


VAERS ID: 315202 (history)  
Form: Version 1.0  
Age: 4.0  
Gender: Female  
Location: New York  
Vaccinated:2008-05-30
Onset:2008-05-31
   Days after vaccination:1
Submitted: 2008-06-06
   Days after onset:6
Entered: 2008-06-06
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
DTAP: DTAP (DAPTACEL) / SANOFI PASTEUR C2953AA / 5 LA / UN
IPV: POLIO VIRUS, INACT. (IPOL) / SANOFI PASTEUR A0474 / 4 LA / UN
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 0454X / 2 RA / UN
VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. 1854U / 2 RA / UN

Administered by: Private       Purchased by: Private
Symptoms: Blood urine present, Contusion, Ear pain, Full blood count, Idiopathic thrombocytopenic purpura, Injection site bruising
SMQs:, Haemorrhage terms (excl laboratory terms) (narrow), Haemorrhage laboratory terms (narrow), Accidents and injuries (narrow), Hypersensitivity (narrow)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: None
Current Illness: None
Preexisting Conditions: Hives on Amoxicillin 11/8/05
Allergies:
Diagnostic Lab Data: CBC; U/A - Blood 3+
CDC Split Type:

Write-up: Patient seen 5/30/08 for her routine kindergarten physical - no concerns noted, left. On 5/31, mom noted some bruising near shot site then noticed bruising on shoulders and skin. Continued to spread. By 6/4/08 c/o of ear pain and was seen in office. Diagnosed with ITP.


VAERS ID: 316769 (history)  
Form: Version 1.0  
Age: 1.0  
Gender: Female  
Location: Oregon  
Vaccinated:2008-06-11
Onset:2008-06-16
   Days after vaccination:5
Submitted: 2008-06-20
   Days after onset:4
Entered: 2008-06-20
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMRV: MEASLES + MUMPS + RUBELLA + VARICELLA (PROQUAD) / MERCK & CO. INC. 0910U / 1 LL / SC

Administered by: Public       Purchased by: Public
Symptoms: Crying, Decreased appetite, Emotional distress, Erythema, Full blood count, Haematocrit normal, Haemoglobin normal, Idiopathic thrombocytopenic purpura, Irritability, Petechiae, Platelet count decreased, Pyrexia, Rash, White blood cell count normal
SMQs:, Anaphylactic reaction (broad), Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Hostility/aggression (broad), Depression (excl suicide and self injury) (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (narrow), Hypoglycaemia (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: POLYVIFLOR 0.25 QD
Current Illness: None
Preexisting Conditions: Eczema; underweight
Allergies:
Diagnostic Lab Data: ER 6/18/08: CBC with WBC 6900; hgb 11.3; hct 33.8%; platelets 2000
CDC Split Type:

Write-up: 6/1708- 6:12pm TC from mom reporting rash increasing flat red spots over body - started night before. 6/18/08 at 10:45am seen by Dr. -S: hx of fever & irritability x2 nights; decreased appetite. O: crying, inconsolable; petechiae up to 3 (most pinpoint) on trunk, face, neck & extremities. Referred to local ER; discharge dx ITP - given 20cc of NS & ROCEPHIN. Clinically looks great at discharge. F/U appt 6-23-08.


VAERS ID: 317885 (history)  
Form: Version 1.0  
Age: 1.0  
Gender: Female  
Location: Oregon  
Vaccinated:2008-06-11
Onset:2008-06-16
   Days after vaccination:5
Submitted: 2008-06-20
   Days after onset:4
Entered: 2008-06-30
   Days after submission:10
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MMRV: MEASLES + MUMPS + RUBELLA + VARICELLA (PROQUAD) / MERCK & CO. INC. 0910U / 1 LL / SC

Administered by: Public       Purchased by: Public
Symptoms: Crying, Decreased appetite, Haematocrit normal, Haemoglobin normal, Idiopathic thrombocytopenic purpura, Irritability, Petechiae, Platelet count decreased, Pyrexia, Rash, White blood cell count
SMQs:, Anaphylactic reaction (broad), Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Hostility/aggression (broad), Depression (excl suicide and self injury) (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (narrow), Hypoglycaemia (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Polyviflor 0.25 QD
Current Illness: None
Preexisting Conditions: Eczema; Underweight
Allergies:
Diagnostic Lab Data: ER 6/18/08: CBC with WBC 6900; HGB 11.3; HCT 33.89; Platelets 2000.
CDC Split Type: OR200815

Write-up: 6/17/08 - 6:12pm TC from mom reporting rash, increased flat red spots over body - started night before. 6/18/08 around 10:45 am seen by doctor - symptoms: history of fever and irritability for 2 nights; decreased appetite. O: crying, inconsolable; petechiae up to 3 inches (most pinpoint) on trunk, face, neck and extremities. Referred to local ER, discharge diagnosis ITP - given 20cc/k of NS and Rocephin. Clinically looks great at discharge. F/U appointment 6-23-08.


VAERS ID: 318045 (history)  
Form: Version 1.0  
Age: 4.0  
Gender: Male  
Location: New York  
Vaccinated:2008-05-05
Onset:2008-05-14
   Days after vaccination:9
Submitted: 2008-07-01
   Days after onset:48
Entered: 2008-07-01
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
DTAP: DTAP (DAPTACEL) / SANOFI PASTEUR C2798AA / 5 RA / IM
IPV: POLIO VIRUS, INACT. (IPOL) / SANOFI PASTEUR A0490 / 4 LA / IM
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 1324F / 2 RA / SC
VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. 1360U / 2 LA / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: Full blood count, Idiopathic thrombocytopenic purpura, Smear test
SMQs:, Haemorrhage terms (excl laboratory terms) (narrow), Hypersensitivity (narrow)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 2 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: Pulmicort, Xopenex, Concerta, Singulair
Current Illness: None
Preexisting Conditions: Asthma; ADHD, combined type; Static encephalopathy with mild developmental delays secondary to Shaken Baby Syndrome. PMH: Shaken Baby syndrome, developmental delays, ADHD. allergies
Allergies:
Diagnostic Lab Data: CBC including platelet count, peripheral smear. Labs and Diagnostics: Platelet counts 6-18K up to 54K by D/c.
CDC Split Type:

Write-up: Patient developed ITP 9 days after immunization. 07/14/2008 MR received for DOS 5/15-16/2008 with DX: ITP. Pt presented after low platelet count discovered on routine labwork. Parent reports increased bruising recently. PE (+) for echymoses on the legs, and scattered purpura and petechiae all over. Admitted for IVIG. Platelets up to 54K on d/C day.


VAERS ID: 318549 (history)  
Form: Version 1.0  
Age: 62.0  
Gender: Female  
Location: California  
Vaccinated:2008-03-01
Onset:2008-06-01
   Days after vaccination:92
Submitted: 2008-07-08
   Days after onset:37
Entered: 2008-07-09
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
VARZOS: ZOSTER (ZOSTAVAX) / MERCK & CO. INC. - / UNK UN / UN

Administered by: Other       Purchased by: Other
Symptoms: Anaemia, Aplastic anaemia, Biopsy bone marrow abnormal, Neutrophil count decreased, Thrombocytopenia
SMQs:, Agranulocytosis (narrow), Haematopoietic cytopenias affecting more than one type of blood cell (narrow), Haematopoietic erythropenia (narrow), Haematopoietic leukopenia (narrow), Haematopoietic thrombocytopenia (narrow), Systemic lupus erythematosus (broad), Malignancy related therapeutic and diagnostic procedures (narrow), Malignant lymphomas (broad), Myelodysplastic syndrome (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: bone marrow biopsy, aplastic anemia; absolute neutrophil, under 500
CDC Split Type: WAES0807USA00307

Write-up: Information has been received from a physician concerning a 62 year old healthy female who in March 2008, was vaccinated with a dose of ZOSTAVAX (Oka/Merck). In June 2008, the patient was diagnosed with aplaestic anemia, after presenting with anemia, thrombocytopenia, and Absolute Neutrophil Count (ANC) under 500, with a bone marrow biopsy consistent with that diagnosis. The patient was noted to be anemic on a blood draw in April (done in anticipation of blood donation). At the time of this report, the outcome was unknown. Upon internal review, aplastic anemia was determined to be an other important medical event. Additional information has been requested.


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