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Found 928 cases where Symptom is Idiopathic t hrombocytopenic purpura or Thrombocytopenia or Th rombocytopenic purpura and Vaccination Date on/after '2006-06-01'

Case Details

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VAERS ID: 290452 (history)  
Age: 77.0  
Gender: Female  
Location: Michigan  
Vaccinated:2007-08-27
Onset:2007-09-01
   Days after vaccination:5
Submitted: 2007-09-12
   Days after onset:11
Entered: 2007-09-13
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
VARZOS: ZOSTER (ZOSTAVAX) / MERCK & CO. INC. - / - UN / UN

Administered by: Other       Purchased by: Other
Symptoms: Blood culture, Blood culture negative, Nausea, Platelet count decreased, Thrombocytopenia
SMQs:, Acute pancreatitis (broad), Haematopoietic thrombocytopenia (narrow), Systemic lupus erythematosus (broad), Gastrointestinal nonspecific symptoms and therapeutic procedures (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? Yes
ER or Doctor Visit? Yes
Hospitalized? Yes, 3 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: [therapy unspecified]
Current Illness: Hypertension
Preexisting Conditions: PMH: HTN, H. pylori, GERD, high cholesterol, arthritis
Diagnostic Lab Data: blood culture - no infection, platelet count 70000 LABS: Blood c/s neg. Urine c/s gram positive cocci. Phosphorous 1.7(L). LFTs elevated. CXR WNL. Platelets 71. WBC 5.7. Rapid strep neg. IgG 499 (L). IgM 361 (H). Varicella IgG & IgM (+)
CDC Split Type: WAES0709USA00813

Write-up: Information has been received from a physician concerning a 77 year old female with hypertension and no known allergies who on approximately 27-AUG-2007 was vaccinated with a single dose of Zostavax (Oka/Merck). Concomitant therapy included unspecified blood pressure medication. On an unspecified night (not the same night as the vaccination) after having dinner the patient developed nausea. The patient sought medical attention at the hospital and food poisoning was ruled out. Blood work revealed the patient had thrombocytopenia, platelet count 70,000 and blood culture revealed no infection. She was admitted to the hospital. The patient had no rash. The patient "is slightly getting better" since being admitted to the hospital. No further information was provided. There was no product quality complaint involved. The patient''s thrombocytopenia and nausea were considered serious for hospitalization. Additional information has been requested. 10/8/07 Patient demographics provided by CDC. 10/16/07 Reviewed hospital medical records which reveal patient experienced low blood pressure, nausea, vomiting, fever, fatigue, sore throat, dizziness, syncope. Exam revealed hypotension, throat erythema & vesicular lesions in mouth/throat. Admitted 9/5-9/8/2007. Tx w/IV antibiotics & antivirals FINAL DX: UTI, septic shock, acute renal failure, thrombocytopenia secondary to septic shock.


VAERS ID: 290787 (history)  
Age: 11.0  
Gender: Male  
Location: Ohio  
Vaccinated:2007-09-06
Onset:2007-09-15
   Days after vaccination:9
Submitted: 2007-09-18
   Days after onset:3
Entered: 2007-09-18
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
TDAP: TDAP (ADACEL) / SANOFI PASTEUR C2632AA / 0 RA / IM

Administered by: Private       Purchased by: Private
Symptoms: Idiopathic thrombocytopenic purpura, Petechiae
SMQs:, Haemorrhage terms (excl laboratory terms) (narrow), Hypersensitivity (narrow)

Life Threatening? Yes
Died? No
Permanent Disability? No
Recovered? Yes
ER or Doctor Visit? Yes
Hospitalized? Yes, 2 days
   Extended hospital stay? No
Previous Vaccinations: ITP (VAERS 179311)~DTaP (no brand name)~5~5.00~Patient
Other Medications: None
Current Illness: None
Preexisting Conditions: PMH: ITP 2001 following DTap, IPV, MMR.
Diagnostic Lab Data: Platelet count 9-16-07 3 (Normal 130-400). Labs and Diagnostics: Platelets counts 20K, 4K, up to 34K prior to d/c. IgE high 263. IgG low 713. C4 Complement low 15. Flow cytometry Peripheral T/B Immunophenotype with Lymphocytes low 7, Absolute Lymphocytes low at 896, Absolute CD3 low at 643 and Absolute CD4 low 387, otherwise WNL. Stool Guiac (+).
CDC Split Type:

Write-up: Pt found to have extensive petechial rash 9 days after receiving Tdap. Admitted for ITP to hospital. 11/21/2007 MR received for DOS 9/16-18/2007 with D/C DX: ITP. Child with hx of ITP following vaccines in 2001 (VAERS 179311) presented with platelet count of 3,000 and petechial rash on feet and legs. Pt had a 30 minute nosebleed which was diffficult to control. Admitted to current hospital with platelet count of 20,000. Pt reported high fever with rigors on day of tetanus booster 9/6/07 and currently c/o nasal congestion, rhinorhea, and a sore throat. Pt txd with IVIG with increase in platelets.


VAERS ID: 291643 (history)  
Age: 1.0  
Gender: Male  
Location: Pennsylvania  
Vaccinated:2007-06-01
Onset:2007-06-27
   Days after vaccination:26
Submitted: 2007-09-28
   Days after onset:93
Entered: 2007-09-28
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEPA: HEP A (VAQTA) / MERCK & CO. INC. 0246U / 0 RA / IM
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 1323F / 0 RA / SC
VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. 0444U / 0 LA / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: Idiopathic thrombocytopenic purpura, Immunoglobulins, Platelet count decreased
SMQs:, Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? Yes, 4 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: none
Current Illness: none
Preexisting Conditions: none PMH: URI, pharyngitis several weeks prior to admit.
Diagnostic Lab Data: LABS: platelets 3. LDH 967 (H).
CDC Split Type:

Write-up: Patient developed Idiopathic thrombocytopenia within 30 days of receiving the MMR vaccine. He has required immunglobulin multiple times. At 16 months of age he continues to have low platelet counts, is at risk for bleeding diathesis. 11/2/07 Reviewed hospital medical records which reveal patient experienced progressive bruising over 3 day period on bilateral LEs. Developed additional bruising over arms, trunk & nose w/nosebleed. Admitted 6/25-6/28/07. Exam revealed petechiae of hard palate as well as multiple ecchymosis & petechaie. Received IVIG x 2 doses. Improved & d/c to home w/helmet, f/u labs & hematology clinic. FINAL DX: Immune thrombocytopenic purpura.


VAERS ID: 292253 (history)  
Age: 17.0  
Gender: Female  
Location: New York  
Vaccinated:2007-04-30
Onset:2007-05-04
   Days after vaccination:4
Submitted: 2007-09-28
   Days after onset:147
Entered: 2007-10-05
   Days after submission:7
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / - UN / UN
MNQ: MENINGOCOCCAL CONJUGATE (MENACTRA) / SANOFI PASTEUR - / - UN / UN

Administered by: Private       Purchased by: Private
Symptoms: Contusion, Petechiae, Platelet count decreased, Thrombocytopenia
SMQs:, Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Accidents and injuries (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness: 10/7/06 - Virus 11/15/06 - Fever 5/4/07 Bruises
Preexisting Conditions: None
Diagnostic Lab Data: Chronic thrombocytopenia Low platelet count from (3,000) - no medication is causing remission 12/26/07-records received-a positive anti-gliadin antibody, a borderline H. Pylori serum antigen and a normal tissue transglutaminase.platelets fluctuate between 3 and 110.
CDC Split Type:

Write-up: Pronounced bruising then developed petechiae on ankles shoulders, neck, torso and face. Called Dr. (internist) in June-took blood 6/22/07-Blood work revealed thrombocytopenia at (8000) immediately went to Oncologist Dr. Levels went to (3,000) on (win Ro) Prednisone since 6/25 to present. 10/15/07-records received- office visit 5/4/07-C/O irregular menses. First and second doses of Gardisil no complaints. Note on 6/13/07-C/O easy bruising, dots on skin more on legs than anywhere else. Positive ecchymosis, petcchia. To see hematologist. 12/26/07-records received for DOS 6/25-11/9/07-Receiving WINRHO. Gastroenterology consultation 12/14/07-presented with ITP, No abdominal pain, fever, weight loss, early stiety, anoreixia, nausea, vomiting, melena, hematemesis, rectal bleed. PE: enlarged thyroid. Impression:eradicationof H. pylori may be associated with improvement of ITP. 1/12/2010 According to various health professionals. The Gardasil shots is the primary cause for my daughter''s immune dysfunction. My daughter did not have any prior illness that caused her present condition of (ITP).


VAERS ID: 295404 (history)  
Age: 75.0  
Gender: Female  
Location: D.C.  
Vaccinated:2007-10-10
Onset:2007-10-20
   Days after vaccination:10
Submitted: 2007-11-02
   Days after onset:13
Entered: 2007-11-02
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
FLU3: INFLUENZA (SEASONAL) (FLULAVAL) / GLAXOSMITHKLINE BIOLOGICALS AFLLA055AA / - UN / IM

Administered by: Private       Purchased by: Private
Symptoms: Activated partial thromboplastin time, Antinuclear antibody, Contusion, Epistaxis, Full blood count, Haematoma, Mouth ulceration, Petechiae, Prothrombin time, Rash macular, Skin discolouration, Thrombocytopenia
SMQs:, Severe cutaneous adverse reactions (broad), Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Oropharyngeal conditions (excl neoplasms, infections and allergies) (narrow), Accidents and injuries (narrow), Hypotonic-hyporesponsive episode (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? No
Hospitalized? Yes, 2 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: SYNTHROID; ZYRTEC; HCTZ/ Triam; Sonata; Vitamin
Current Illness:
Preexisting Conditions: Chronic fatigue; LBBB; Hypothyroidism; HBP; NKDA PMH: HTN, IBS, sleep disorder, hives (dermagraphia),hand tremor x 2 yrs, L$gR. depression. Granddaugher w/platelet disorder.
Diagnostic Lab Data: CBC, CMP, PT, PTT and ANA LABS: platelets 14,000. Bone marrow biopsy revealed reactive disease c/w ineffective thrombopoiesis or peripheral destruction of platelets. LABS: 10/23 plts 3K. Bone marrow biopsy revealed megakaryocytic hyperplasia. Plts 10/26 48K.
CDC Split Type:

Write-up: The patient states that over the last one to two days she has noticed a marked proliferation of tiny red spots all over her body. She also points out a blood blister on the buccal mucosa and she has had some nosebleeds. She is also bruising more easily. There is no prior history of this. She has a granddaughter who has had platelet disorder. Appears in no acute distress. Temp-97.7. Pulse-80. Blood pressure-130/80. The patient has diffuse petechial rash most marked on the lower extremities. There is an approximately silver-dollar sized hematoma in the right buccal mucosa. There was some purplish discoloration on the back of one hand, but no frank ecchymoses. Probable thrombocytopenia. 11/6/07 Reviewed hospital medical records which reveal patient experienced diffuse petechiae, blood blisters x 3-4 days & nose bleed x 1 day when seen in clinic 10/24/2007. Admitted 11/2-11/4/2007. Tx w/IVIG x 2 & steroids. FINAL DX: ITP. 12/21/07 Reviewed pcp medical records which reveal patient experienced marked proliferation of tiny red spots all over body x 2 days when seen in office 10/23/07. Also w/blood blister on buccal mucosa, nosebleeds & easy bruising. Dx of probable thrombocytopenia. Referred to hematologist & labs done. When seen 11/13 had be on IVIG & steroids for ITP, possibly related to flu vax. IVIG failed by 11/29 visit & was being tx w/Rituxan x 4 doses & steroids. Initially responded to tx but by 12/6/07 splenectomy recommended. When seen initially by hematologist on 10/24, direct admit to hospital for IVIG x 2. Bone marrow biopsy done. D/c home on continued steroids & home infused IVIG weekly. Referred to surgeon for possible splenectomy. FINAL DX: severe thrombocytopenia.


VAERS ID: 296568 (history)  
Age: 1.06  
Gender: Male  
Location: Kentucky  
Vaccinated:2007-10-12
Onset:2007-10-31
   Days after vaccination:19
Submitted: 2007-11-13
   Days after onset:13
Entered: 2007-11-13
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
FLUX: INFLUENZA (SEASONAL) (NO BRAND NAME) / UNKNOWN MANUFACTURER - / 0 LA / UN
HEPA: HEP A (NO BRAND NAME) / UNKNOWN MANUFACTURER - / 0 RL / UN
MMR: MEASLES + MUMPS + RUBELLA (NO BRAND NAME) / UNKNOWN MANUFACTURER - / 0 LA / UN
VARCEL: VARICELLA (NO BRAND NAME) / UNKNOWN MANUFACTURER - / 0 RA / UN

Administered by: Unknown       Purchased by: Unknown
Symptoms: Idiopathic thrombocytopenic purpura, Immunoglobulins, Petechiae, Platelet count decreased
SMQs:, Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? No
Hospitalized? Yes, 4 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: Dimeatapp for a cold.
Current Illness: He had a cold 11/30/07-records received- Mild upper respiratory symptoms 2 weeks ago.
Preexisting Conditions: Heart Mumor
Diagnostic Lab Data: On 10-31-2007 his Platelet count was 6. While at they done lab work 11-02-2007 his platelets were 8. Then on 11-04-2007 his platelets were 6 again. On 11-06-2007 after IVIG his platelets were 51. Then on 11-08-2007 they were 293. He has to have more labs on 11-15-2007. He was diagnosed with Immune Thrombocytopenia Purpura. 11/30/07-records received-WBC 15.8, lymphocyte 65. Platelets 6000. On second admission platelets 5000.
CDC Split Type:

Write-up: Patient received his shots on Oct. 12, 2007. On Oct. 30, 2007 my husband and I noticed that he had a bruise and could not figure out how he got it. Then the next morning he had petechiae on his feet and legs.He also got another bruise between that night and morning. We took him to see Dr. He sent us to the Lab to get A CBC. His platelets were 6. He then called the Hospital and they told us to bring him on down there. 11/30/07-records received for DOS 10/31-11/207 and 11/4-11/6/07-DC DX: for both admissions:Idiopathic thrombocytopenic purpura. Anemia and Acute otitis media. Admitted for increasing bruising and low platelets. Increased bruising noted past 2 days. Prior to second admission fussy and pulling at his eat. Treated with WinRho and IVIG.


VAERS ID: 296854 (history)  
Age: 1.0  
Gender: Female  
Location: Florida  
Vaccinated:2007-09-11
Onset:2007-10-29
   Days after vaccination:48
Submitted: 2007-11-07
   Days after onset:9
Entered: 2007-11-15
   Days after submission:8
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEPA: HEP A (VAQTA) / MERCK & CO. INC. 10270U / 0 UN / UN
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 0424U / 0 UN / UN
VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. AHAVB182 / 0 UN / UN

Administered by: Private       Purchased by: Unknown
Symptoms: Full blood count, Idiopathic thrombocytopenic purpura, Platelet count, Pruritus
SMQs:, Anaphylactic reaction (broad), Haemorrhage terms (excl laboratory terms) (narrow), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? Yes
ER or Doctor Visit? Yes
Hospitalized? Yes, 2 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications:
Current Illness: No
Preexisting Conditions: No
Diagnostic Lab Data: CBC-Platelets-1 12/12/07-records received- Platelets 21,000 and 7,000, eosinophils 6. BUN/creat ratio 42.5. LDH 389.
CDC Split Type:

Write-up: 18 days after vaccine developed pruritic spots. Admitted to Diagnosis: ITP. 12/12/07-records received for DOS 9/29-10/1/07-DC DX: Acute idiopathic thrombocytopenic purpura, questionable measles/mumps/rubella induced. C/O rash started 6 days prior to admission. Petechia all over face and body.


VAERS ID: 297730 (history)  
Age: 15.0  
Gender: Female  
Location: Texas  
Vaccinated:2007-08-02
Onset:2007-08-17
   Days after vaccination:15
Submitted: 2007-11-26
   Days after onset:101
Entered: 2007-11-26
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. 0927U / 1 LA / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Acne, Idiopathic thrombocytopenic purpura, Immunoglobulins, Menorrhagia, Platelet count decreased, Pruritus generalised
SMQs:, Anaphylactic reaction (broad), Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? No
ER or Doctor Visit? Yes
Hospitalized? No
Previous Vaccinations: See remarks above~ ()~~0.00~In Patient|none~ ()~~0.00~In Sibling
Other Medications:
Current Illness: None
Preexisting Conditions: None PMH: heavy painful menses x 1 year. Dizziness & fainting during periods. Allergy to ceclor, hives. Mild HTN. Facial acne & on tetracycline.
Diagnostic Lab Data: Blood examinations (labs) taken at Hospital LABS: 10/4/07: WBC 19.16 (H), H/H 14.2/42.1 (N), plts 48K. 10/26/07: WBC 6.29 (N), H/H 12.4/36.5 (N), plts 43K. 11/9/07: H/H 12.4/35 (L), plts 232K (N). Throat c/s neg for strep. 11/30/07: UA WNL. Sed rate & chem WNL. WBC 4.24 (L), H/H 12.9/37.9 (N), plts 203 (N). 12/21/07: plts 233 (N). 12/12/07: pelvic US endometrial stripe thinner than on prior study of 8/24/07.
CDC Split Type:

Write-up: 5/18/07 patient given first Gardasil(HPV) lot 1447F. 8/2/07 patient given second Gardasil (HPV lot 09270 mfg Merck. 8/17/07 - Patient taken to Tx Hosp Emerg Room for excesssive bleeding related to menstrual cycle. Blood test reveals platelet level approx 32K. ITP diagnosed. Platelet level would go down to 2K on 9/4/07. Treatments given have been Immune Globulin, WinRHO, and Prednisone. Patient on birth control pills to stop bleeding. Latest lab taken show level at 232K, first time over 100K since mid-August. At present, patient still has some itching (all over) and acne on face (from medicines?). Still monitoring platelet level - hope this nightmare is over. Sister age 12 (at time) received same HPV vaccinations with no adverse reaction so far. Not certain about Route in quest #13. 12/18/07 Reviewed hospital ER & Clinic medical records which reveal patient experienced heavy menses with clots & went to ER 8/17/07. Tx w/tapering steroidsReferred to Heme, GYN & PMD. Clinic records of 9/20-12/12/2007 indicate patient bleeding controlled w/low dose estrogen. Plts max low 2k on 9/4 w/bruising & petechiae. Received IVIG 9/7 x 1, plts rose to 16k. . Received WinRho 9/11 & plts rose to 28k. 9/20 plts 12k, tx w/tapering steroids until 10/21. 11/9 plts 232k but restarted steroid taper for 2 more wks. 11/30 plts 203k & plan was to observe off meds. No labs reported on 12/12 visit. ER DX: thrombocytopenia & menorrhagia, hemodynamically stable. 2/22/08 Reviewed pcp medical records & vax records. Corrected lot # in database. Received initial HPV vax on 5/18/07, IM in left arm, lot # 1447E. On 8/2/07 c/o nausea & dizziness s/p 1st HPV vax. Vomiting w/each period & felt dizzy, cramping & heavy periods. To see GYN if anti-inflammatories not helpful. Office vs of 8/20 revealed pt w/ very heavy mentstuation & epistaxis. Seen in ER where plt ct 36K. Referred to GYN. Returned to office 9/5/07 s/p dx w/ITP, plts 2K & had received IVIG. 9/14 plts 28K per t/c. 11/7/07 vs for stuffy runny nose, sore throat & urticarial rash on back. Dx w/URI, urticaria, thrombocytopenia. Last plt ct noted as 43K on BCP. FINAL DX: Idiopathic thrombocytopenic purpura.


VAERS ID: 297837 (history)  
Age: 15.0  
Gender: Male  
Location: Unknown  
Vaccinated:2007-10-11
Onset:2007-10-21
   Days after vaccination:10
Submitted: 2007-10-31
   Days after onset:10
Entered: 2007-11-26
   Days after submission:26
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
FLU3: INFLUENZA (SEASONAL) (FLUZONE) / SANOFI PASTEUR U2452AA / - UN / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Platelet count decreased, Thrombocytopenia
SMQs:, Haematopoietic thrombocytopenia (narrow), Systemic lupus erythematosus (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Died? No
Permanent Disability? No
Recovered? Yes
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness: Acne
Preexisting Conditions: Acne
Diagnostic Lab Data: Platelets 66k 10-21-07;platelets 190k 10-28-07
CDC Split Type:

Write-up: Thrombocytopenia - transient


VAERS ID: 300040 (history)  
Age: 33.0  
Gender: Female  
Location: Maryland  
Vaccinated:2007-11-07
Onset:2007-11-14
   Days after vaccination:7
Submitted: 2007-12-17
   Days after onset:33
Entered: 2007-12-17
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
FLUX: INFLUENZA (SEASONAL) (NO BRAND NAME) / UNKNOWN MANUFACTURER UNKNOWN / - UN / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Aspiration bone marrow, Biopsy bone marrow, Blood culture negative, Coagulation test, Coombs indirect test negative, Haematuria, Menorrhagia, Platelet count decreased, Postpartum state, Purpura, Red blood cells urine positive, Thrombocytopenia, Urine analysis abnormal, Virus serology test negative
SMQs:, Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Normal pregnancy conditions and outcomes (narrow), Chronic kidney disease (broad), Tubulointerstitial diseases (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Died? No
Permanent Disability? No
Recovered? Yes
ER or Doctor Visit? Yes
Hospitalized? Yes, 2 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: None
Current Illness: None
Preexisting Conditions: PMH: 6 mos post partum via c-section. Chronic recurrent sinusitis w/recently resolved sinus congestion. Seasonal allergies. Asthma in remote past. Sinus surgery. Family hx of cardiac disease.
Diagnostic Lab Data: Thrombocytopenia as mentioned under (7). Viral serologies negative for CMV/EBV/Hepatitis viruses?Parvovirus/Rubella. Hematuria with Tntc (too numerous to count) RBCs on U/A. Blood culture -ve x1. Indirect Coombs test -ve. DIC panel -ve. Bone marrow biopsy and aspirate results pending. LABS: Initial plts 1,000. Final plts 11,000. CXR WNL.
CDC Split Type:

Write-up: Postpartum month 6. Menorrhagia and purpuric rash over legs and oral mucosa about 1 week after vaccine administration. Thrombocytopenia on labs - 1000 platelet count. Given prednisone 100 mg by mouth daily. Platelet count rose to 37,000 in 10 days, but then started dropping again and in another 11 days was down to 8000. Given Anti-D Immune globulin- platelets rose to 87,000 2 days later and to 421,000 1 week after the Anti-D. 1/18/08 Reviewed hospital medical records which reveal patient experienced extremely heavy menstrual flow beginning on 11/6/07. Next day she noted red spots on legs & oral mucosa, called her pcp who sent her to ER. Exam revealed petechial rash & bruises. Heme consult obtained. Tx w/IV steroids w/improvement. D/C to home on oral steroids w/heme f/u. FINAL DX: thrombocytopenia, possibly idiopathic thrombocytopenic purpura; hypocalcemia, resolved.


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