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Found 963 cases where Symptom is Idiopathic t hrombocytopenic purpura or Thrombocytopenia or Th rombocytopenic purpura and Vaccination Date on/after '2006-06-01'

Case Details

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VAERS ID: 280702 (history)  
Form: Version 1.0  
Age: 29.0  
Gender: Female  
Location: Florida  
Vaccinated:2007-05-21
Onset:2007-05-22
   Days after vaccination:1
Submitted: 2007-06-06
   Days after onset:15
Entered: 2007-06-06
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEP: HEP B (ENGERIX-B) / GLAXOSMITHKLINE BIOLOGICALS AHBVB377AA / 1 LA / IM
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. 1182F / 2 RA / SC

Administered by: Unknown       Purchased by: Unknown
Symptoms: Contusion, Feeling abnormal, Haematoma, Pyrexia, Rash, Thrombocytopenic purpura
SMQs:, Anaphylactic reaction (broad), Haemorrhage terms (excl laboratory terms) (narrow), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Dementia (broad), Accidents and injuries (narrow), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, 3 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: BIRTH CONTROL PILLS
Current Illness: none records received 9/21/07-For last 8 days prior to ER visit taking antibiotics similar to Bactrim from Russia. Recent history of upper respiratory infection.
Preexisting Conditions: none known
Allergies:
Diagnostic Lab Data: none available 9/21/07-records received-WBC 3.3, platelets 3000. CMP within normal limits. Blood culture negative.
CDC Split Type:

Write-up: Patient received Hep B vaccine and MMR vaccine on Monday, May 21, 2007. By the next day, she began to feel "bad" and have fever. By Friday, May 25, 2007, she found a rash on her legs and bruises/hematomas all over her body. She went an emergency department where she was admitted to hospital x 4 days. She was treated with transfusions and steroids and discharged with a diagnosis of "immune thrombocytopenic purpura" by pt. report. Patient came to our office on 6-05 when she looked well, but some bruising remained. 9/21/07-records received for DOS 5/25-5/28/07. DC DX: Immune thrombocytopenia probably secondary to measles, mumps, rubella vaccination. C/O bruising and multiple rashes over bilateral extremities. PE: Petechial rashes on lower extremities, bruises with ecchymosis over bilateral hip area and elbows.


VAERS ID: 281380 (history)  
Form: Version 1.0  
Age: 17.0  
Gender: Female  
Location: New York  
Vaccinated:2007-04-19
Onset:2007-05-01
   Days after vaccination:12
Submitted: 2007-06-08
   Days after onset:38
Entered: 2007-06-12
   Days after submission:4
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
MNQ: MENINGOCOCCAL CONJUGATE (MENACTRA) / SANOFI PASTEUR U2135AA / UNK LA / IM

Administered by: Private       Purchased by: Private
Symptoms: Haematocrit decreased, Haemoglobin decreased, Idiopathic thrombocytopenic purpura, Papillitis, Papilloedema, Platelet count decreased, Scotoma, Visual disturbance
SMQs:, Haematopoietic erythropenia (broad), Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Haemorrhage laboratory terms (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Glaucoma (broad), Optic nerve disorders (narrow), Lens disorders (broad), Retinal disorders (broad), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Hypoglycaemia (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, 2 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications:
Current Illness: None
Preexisting Conditions: PCOS metabolic syndrome with increased level insulin resistance
Allergies:
Diagnostic Lab Data: Platelet count 12,000, HGB 10.5, HCT 35 records received 6/20/07-Labs: Plateletes 12,000. Hemoglobin 10.5, hematocrit 30. PT 12.8. EBV negative. Mono screen negative. Seen in ER MRI brain showed an incidental pineal cyst. Spinal tap negative.
CDC Split Type:

Write-up: Idiopathic thrombocytopenia, vesical scotamate-papilledema bilaterally or papillite bilaterally also received a PPD on same day as Menactra. 6/20/07-records received for DOS-05/02-05/04/07-DC DX:Idiopathic Thrombocytopenia Purpura. Presented to ER with hsitory of bruising of the lower extremities with petechial type rash, rash of lower extremities particularly of ankles and mid calf. C/O aches and pain prior to presentation of rash. Treated with IVIG and after second dose complained of headache. Seen after discharge by neurologist. Complained of headaches and vomiting and low grade fevers which persisted for couple of weeks. Experienced visual scotomata in form of green spots and saw an ophthalmologist who diagnosed bilateral papilledema. Visual symptoms resolved and on revisit to ophth. diagnosed papillitis as opped to papilledema. PE: spontaneous venous pulsations were minimally present bilaterally. No overt features of increased intracranial pressure.


VAERS ID: 281907 (history)  
Form: Version 1.0  
Age: 1.0  
Gender: Female  
Location: Connecticut  
Vaccinated:2007-03-20
Onset:2007-04-02
   Days after vaccination:13
Submitted: 2007-06-14
   Days after onset:73
Entered: 2007-06-15
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HEPA: HEP A (NO BRAND NAME) / UNKNOWN MANUFACTURER - / 2 UN / UN
MMR: MEASLES + MUMPS + RUBELLA (MMR II) / MERCK & CO. INC. - / 2 UN / UN
PNC: PNEUMO (PREVNAR) / PFIZER/WYETH - / 4 - / IM
VARCEL: VARICELLA (VARIVAX) / MERCK & CO. INC. - / 2 UN / UN

Administered by: Private       Purchased by: Private
Symptoms: Blood culture positive, Dialysis, Haemolytic anaemia, Haemolytic uraemic syndrome, Hepatic failure, Mechanical ventilation, Pneumococcal bacteraemia, Pneumonia pneumococcal, Pneumonia streptococcal, Pyrexia, Respiratory failure, Thrombocytopenia, Transfusion, Vaccination failure
SMQs:, Acute renal failure (narrow), Hepatic failure, fibrosis and cirrhosis and other liver damage-related conditions (narrow), Haemolytic disorders (narrow), Anaphylactic reaction (broad), Haematopoietic thrombocytopenia (narrow), Lack of efficacy/effect (narrow), Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Shock-associated circulatory or cardiac conditions (excl torsade de pointes) (broad), Torsade de pointes, shock-associated conditions (broad), Hypovolaemic shock conditions (broad), Toxic-septic shock conditions (broad), Anaphylactic/anaphylactoid shock conditions (broad), Hypoglycaemic and neurogenic shock conditions (broad), Acute central respiratory depression (narrow), Guillain-Barre syndrome (broad), Renovascular disorders (broad), Chronic kidney disease (narrow), Hypersensitivity (broad), Respiratory failure (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (narrow), Infective pneumonia (narrow)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, 30 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness: Unknown
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: Blood culture 04/00/2007 positive for streptococcus pneumoniae
CDC Split Type: HQWYE503106JUN07

Write-up: Information regarding Prevnar vaccine was received from a healthcare professional regarding a 12-month-old female patient who completed her primary series, having received a fourth dose on 20-Mar-2007. The patient also received a dose of Varivax, a second dose of Hepatitis A Vaccine (manufacturer unknown) and a second dose of M-M-R II (Merck Sharp and Dome) on the same day. On 02-APR-2007, the patient was hospitalized for pneumococcal pneumonia, pneumococcal bacteremia, streptococcal pneumoniae induced hemolytic uremic syndrome, respiratory failure and liver failure. On 20-Mar-2007, the patient received a fourth dose of Prevnar, completing her primary series. On 02-Apr-2007, the patient was hospitalized with a fever (temperature not reported), pneumococcal pneumonia, and thrombocytopenia (laboratory values not available). A blood culture was performed and was positive for Streptococcus pneumoniae. No serotype results were available. The patient was diagnosed with Streptococcal pneumoniae induced hemolytic uremic syndrome which included hemolytic anemia requiring multiple blood transfusions, renal failure requiring peritoneal dialysis, respiratory failure requiring intubation for two weeks and liver failure. The patient was hospitalized for four weeks. It was reported she recovered from all events and was discharged to home on 02-May-2007. Discharge medications included Norvasc, Ativan, aspirin, folate and Poly-Vi-Sol. No additional information was available at the time of this report. Blood culture (results: positive for Streptococcus pneumoniae) was done in Apr-2007.


VAERS ID: 283821 (history)  
Form: Version 1.0  
Age: 0.2  
Gender: Male  
Location: Texas  
Vaccinated:2007-04-25
Onset:2007-04-27
   Days after vaccination:2
Submitted: 2007-07-03
   Days after onset:67
Entered: 2007-07-05
   Days after submission:2
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
DTAP: DTAP (DAPTACEL) / SANOFI PASTEUR C2628AA / 1 LL / -
HBHEPB: HIB + HEP B (COMVAX) / MERCK & CO. INC. 1416F / 1 RL / -
IPV: POLIO VIRUS, INACT. (IPOL) / SANOFI PASTEUR Z0548 / 1 LL / -
PNC: PNEUMO (PREVNAR) / PFIZER/WYETH B086848 / 1 RL / -
RV5: ROTAVIRUS (ROTATEQ) / MERCK & CO. INC. 0024U / 1 MO / PO

Administered by: Other       Purchased by: Other
Symptoms: Conjunctivitis, Diarrhoea, Kawasaki's disease, Nasal congestion, Pharyngeal erythema, Pyrexia, Rash, Thrombocytopenia
SMQs:, Severe cutaneous adverse reactions (broad), Anaphylactic reaction (broad), Haematopoietic thrombocytopenia (narrow), Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Pseudomembranous colitis (broad), Oropharyngeal conditions (excl neoplasms, infections and allergies) (narrow), Gastrointestinal nonspecific symptoms and therapeutic procedures (narrow), Vasculitis (narrow), Conjunctival disorders (narrow), Ocular infections (broad), Hypersensitivity (narrow), Noninfectious diarrhoea (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (narrow)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 7 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: aspirin, corticosteroids (unspecified), globulin, immune
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: Unknown records received 7/25/07-Labs elevated CRP and alpha-1 antitrypsin. Stool culture negative. Blood culture negative. Urine culture no organism seen. WBC 20.94, platelet 1242. Mono 9.3CXR viral aiways disease.Echocardiogram revealed coronary ectasia with moderate dilation of left and right coronary arteries with associated aneurysms. Found to have dilation diffuse and along the whole course of the circumflex.
CDC Split Type: WAES0706USA04355

Write-up: Information has been received from a physician concerning a 9 week old male who on 25-APR-2007 was vaccinated with an oral 2 ml dose of Rotateq (Lot# 656194/0024U). Concomitant therapy included aspirin, corticosteroids (unspecified), and globulin, immune, IV. On 27-APR-2007, two days after taking Rotateq the patient had a fever and congestion. Then on 02-MAY-2007 the patient still had a fever and also developed a red throat. When the physician saw the patient on 01-JUN-2007, the fever was still there, and the patient had a rash, congestion, diarrhea, and conjunctivitis in the eyes. On 12-JUN-2007 the patient fever still continued and he had thrombocytopenia. Also on 12-JUN-2007 the patient went to the emergency room. While in the emergency room the patient was diagnosed with Kawaski syndrome. The patient had two huge cornea aneurysms. No product quality complaint was involved. No other information was provided. The patient''s experiences were considered to be life threatening by the reporter. A lot check has been requested. Additional information has been requested. 7/25/07-records received without DC summary. Consulation report 3 month old admitted on 6/13/07 for Kawasaki Disease. Fifteen days prior to admission began with fever max of 102.7 on first day of illness. Daily fevers between 100-101. Fine rash over trunk and dorsum hands. Bilateral conjunctivitis. Over course of illness developed intermittent cracked lips with occasional bleeding followed by pale appearance was reportedly gummy. Cyclic resulting in return of cracked lips and bleeding. Fussy. On day 15 in ED noted to have desquamation of fingertips and toes. RX with IVIG. 12/17/07-DC summary received for DOS 6/13-6/20/07-DC DX Kawasaki Disease


VAERS ID: 285537 (history)  
Form: Version 1.0  
Age: 29.0  
Gender: Male  
Location: California  
Vaccinated:2007-07-09
Onset:2007-07-10
   Days after vaccination:1
Submitted: 2007-07-10
   Days after onset:0
Entered: 2007-07-23
   Days after submission:13
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
TDAP: TDAP (ADACEL) / SANOFI PASTEUR C2758AA / 1 LA / IM

Administered by: Private       Purchased by: Private
Symptoms: Erythema, Oedema, Thrombocytopenic purpura
SMQs:, Cardiac failure (broad), Anaphylactic reaction (broad), Angioedema (broad), Haemorrhage terms (excl laboratory terms) (narrow), Haemodynamic oedema, effusions and fluid overload (narrow), Cardiomyopathy (broad), Hypersensitivity (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness: Puncture wound
Preexisting Conditions: PCN
Allergies:
Diagnostic Lab Data: None
CDC Split Type:

Write-up: + edema, no pitting, mild erythema, mild TTP, no warmth.


VAERS ID: 285901 (history)  
Form: Version 1.0  
Age: 88.0  
Gender: Female  
Location: D.C.  
Vaccinated:2007-05-29
Onset:2007-06-06
   Days after vaccination:8
Submitted: 2007-07-13
   Days after onset:37
Entered: 2007-07-25
   Days after submission:12
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
VARZOS: ZOSTER (ZOSTAVAX) / MERCK & CO. INC. 1411F / 1 UN / SC

Administered by: Military       Purchased by: Military
Symptoms: Biopsy bone marrow abnormal, Blood bilirubin, Blood test normal, Ecchymosis, Petechiae, Platelet count decreased, Renal function test normal, Thrombocytopenia, White blood cell count
SMQs:, Haematopoietic cytopenias affecting more than one type of blood cell (broad), Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Malignancy related therapeutic and diagnostic procedures (narrow), Malignant lymphomas (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, 7 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: Glipizide XL, ca-carbonate, Allegra, mv, Tylenol, guiafenesin, ASA, Vit E, Lantus Insulin, Colace, Lisinopril, Actonel/Risedronate, Tolterodine, Flonase, Simethicone, Milk of Mag, Refresh eye drops, Nifedipine, Metoprolol
Current Illness: Bronchiectasis, NPH c vp Shunt, DM, Peripheral Neuropathy, HLD, GERD, Dementia
Preexisting Conditions: NKDA records received 9/14/07-PMH: bronchiectasis. nph VP shunt. DM. Peripheral neuropathy. GERD demetia.
Allergies:
Diagnostic Lab Data: normal lytes and renal fxn, nl wbc and h/h, nl lft, nl tbili/dbili, nl coags, platelets <10,000 (410,000 baseline plt) bone marrow smear: abnormal appearing basophils and leukocytes, tear drop cells, nucleated red cells, no schistocyes, paucity platelets 287.5 Thrombocytopenia temporally associated to receipt of the Zostavax vaccine and to nifedipine records received 9/14/07- Labs: bone marrow smear, abnormal appearing basophils and leukocytes, tear drop cells, nucleated red cells, no schistocytes, paucity platelets.
CDC Split Type:

Write-up: Thrombocytopenia, Ecchymosis, Petechiae 9/14/07-records received new onset of thrombocytopenia purpura and petechiae, admitted on 6/12/07. One week after receipt of zostavax vaccine developed purpuric lesions on oral mucosa and tongue. Few days later developed diffuse petechial rash on upper and lower extremities and trunk. Received 5 doses of IVIG. Assessment thrombocytopenia temporally associated to receipt of zostavax vaccine and to nefedipine.


VAERS ID: 286366 (history)  
Form: Version 1.0  
Age: 38.0  
Gender: Male  
Location: Unknown  
Vaccinated:2007-05-31
Onset:2007-07-13
   Days after vaccination:43
Submitted: 2007-07-26
   Days after onset:13
Entered: 2007-07-31
   Days after submission:5
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
ANTH: ANTHRAX (BIOTHRAX) / EMERGENT BIOSOLUTIONS FAV106 / 7+ LA / SC

Administered by: Military       Purchased by: Military
Symptoms: Injection site swelling, Leukopenia, Malaise, Myalgia, Platelet count decreased, Rash, Thrombocytopenia, White blood cell count decreased
SMQs:, Rhabdomyolysis/myopathy (broad), Anaphylactic reaction (broad), Haematopoietic leukopenia (narrow), Haematopoietic thrombocytopenia (narrow), Systemic lupus erythematosus (narrow), Extravasation events (injections, infusions and implants) (broad), Haemodynamic oedema, effusions and fluid overload (narrow), Eosinophilic pneumonia (broad), Hypersensitivity (narrow), Tendinopathies and ligament disorders (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: None
Current Illness: None
Preexisting Conditions:
Allergies:
Diagnostic Lab Data: Plts 128, WBC count 2.8
CDC Split Type:

Write-up: Left arm and swelling at injection site, diffuse rash on trunk, malaise and diffuse myalgias. Mild leukopenia and thrombocytopenia.


VAERS ID: 287369 (history)  
Form: Version 1.0  
Age: 23.0  
Gender: Female  
Location: Virginia  
Vaccinated:2007-04-27
Onset:2007-06-01
   Days after vaccination:35
Submitted: 2007-08-06
   Days after onset:66
Entered: 2007-08-08
   Days after submission:2
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 1 - / IM

Administered by: Other       Purchased by: Other
Symptoms: Contusion, Epistaxis, Idiopathic thrombocytopenic purpura, Immunoglobulins, Platelet count decreased
SMQs:, Haematopoietic thrombocytopenia (narrow), Haemorrhage terms (excl laboratory terms) (narrow), Systemic lupus erythematosus (broad), Accidents and injuries (narrow), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? Yes, ? days
   Extended hospital stay? Yes
Previous Vaccinations:
Other Medications: Hormonal contraceptives; Tetracycline
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: Platelet count 06/??/07 - 2000; Platelet count 07/26/07 - 8000
CDC Split Type: WAES0707USA04986

Write-up: Information has been received from a physician concerning a 23 year old female patient who during the last week of April 2007 was vaccinated IM with a first dose of Gardasil. Concomitant therapy included tetanus toxoid, tetracycline and hormonal contraceptives (unspecified brand). In June 2007, the patient developed nose bleed and bruising of her body. The patient''s platelet count reached 2000 and was hospitalized for ITP (Idiopathic Thrombocytopenic Purpura). The patient was treated with intravenous immunoglobulin and high dose corticosteroids (unspecified). The patient responded to the corticosteroids (unspecified) but became intolerant to the side effects. There have been more than one attempts to taper the patient off the corticosteroid but the platelets decreased each time. As of 26-JUL-2007, the patient''s platelet count was 8000. No other details were provided. Physician did not provide specifics on corticosteroid side effects that the patient developed. The patient had not recovered. The events nose bleeds, bruising of patient''s body, and Idiopathic Thrombocytopenic Purpura (ITP) were considered to be life-threatening. Additional information has been requested.


VAERS ID: 288850 (history)  
Form: Version 1.0  
Age: 24.0  
Gender: Male  
Location: Unknown  
Vaccinated:2007-08-08
Onset:2007-08-09
   Days after vaccination:1
Submitted: 2007-08-10
   Days after onset:1
Entered: 2007-08-23
   Days after submission:13
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
ANTH: ANTHRAX (BIOTHRAX) / EMERGENT BIOSOLUTIONS FAV109 / 5 RA / SC

Administered by: Military       Purchased by: Military
Symptoms: Erythema, Idiopathic thrombocytopenic purpura, Joint effusion, Oedema peripheral, Pain in extremity, Skin warm
SMQs:, Cardiac failure (broad), Anaphylactic reaction (broad), Angioedema (broad), Haemorrhage terms (excl laboratory terms) (narrow), Haemodynamic oedema, effusions and fluid overload (narrow), Hypersensitivity (narrow), Arthritis (broad), Tendinopathies and ligament disorders (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness: None
Preexisting Conditions: None
Allergies:
Diagnostic Lab Data: N/A
CDC Split Type:

Write-up: 24 yo male with (R) UE redness, warmth, swelling, and pain x 1 day. Received 5th anthrax vaccination 2 days ago. PE reveals large erythematous and edematous area measuring 31.75 x 18.5 cm with + effusion over elbow and + ITP to post elbow.


VAERS ID: 289355 (history)  
Form: Version 1.0  
Age: 70.0  
Gender: Female  
Location: New York  
Vaccinated:2007-06-15
Onset:2007-07-01
   Days after vaccination:16
Submitted: 2007-08-29
   Days after onset:59
Entered: 2007-08-30
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
VARZOS: ZOSTER (ZOSTAVAX) / MERCK & CO. INC. - / UNK UN / SC

Administered by: Other       Purchased by: Other
Symptoms: Contusion, Drug hypersensitivity, Idiopathic thrombocytopenic purpura, Laboratory test, Platelet count
SMQs:, Angioedema (broad), Haemorrhage terms (excl laboratory terms) (narrow), Accidents and injuries (narrow), Hypersensitivity (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? Yes
Office Visit? No
ER Visit? Yes
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: aspirin; atenolol; TRICOR; gemfibrozil; lisinopril
Current Illness: Drug hypersensitivity
Preexisting Conditions: Idiopathic thrombocytopenia, splenectomy
Allergies:
Diagnostic Lab Data: diagnostic laboratory - results not reported, platelet count - results not reported
CDC Split Type: WAES0708USA04473

Write-up: Information has been received from a registered nurse concerning a 70 year old female with a history of xylocaine allergy, and a splenectomy after idiopathic thrombocytopenia, who in "mid June 2007" was vaccinated SC with a dose of Zostavax. Concomitant therapy included gemfibrozil, lisinopril (manufacturer unknown), Tricor, atenolol and aspirin. The patient was seen by the doctor on 25-JUN-2007 with a 4-5 day history of bruising. The doctor prescribed prednisone as treatment. Lab studies included blood work and platelet counts, results were not reported. The patient also received platelets on multiple occasions as an outpatient. The patient was diagnosed with idiopathic thrombocytopenia "17 days after vaccination." The patient saw a hematologist and an allergist. The patient recovered "about three weeks ago" on approximately 02-AUG-2007. No other information was provided. There was no product quality complaint involved. The reporter considered idiopathic thrombocytopenia to be serious, life threatening, and other important medical events. Additional information has been requested.


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