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Found 413 cases where Vaccine is HPV or HPV2 or HPV4 and Patient Died

Case Details

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VAERS ID: 380081 (history)  
Form: Version 1.0  
Age: 13.0  
Sex: Female  
Location: Foreign  
Vaccinated:2009-07-17
Onset:2009-08-08
   Days after vaccination:22
Submitted: 2010-02-05
   Days after onset:181
Entered: 2010-02-12
   Days after submission:7
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / UNK UN / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Coma, Death, Dyspnoea, Pyrexia
SMQs:, Anaphylactic reaction (broad), Hyperglycaemia/new onset diabetes mellitus (broad), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Acute central respiratory depression (broad), Pulmonary hypertension (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Cardiomyopathy (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Hypoglycaemia (broad)

Life Threatening? Yes
Birth Defect? No
Died? Yes
   Date died: 2009-08-08
   Days after onset: 0
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? Yes, 0 days
   Extended hospital stay? No
Previous Vaccinations:
Other Medications: RANTAC; acetaminophen, aminophylline; chloroquine
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: Unknown
CDC Split Type: WAES1001USA03765

Write-up: Information has been received from a physician concerning a 13 year old school girl studying in class nine of health center. On 17-JUL-2009, patient received first dose of GARDASIL left deltoid. Concomitant medications included chloroquine, RANTAC, paracetamol, "IV fluids RL" and aminophyline drip. During the process of community mobilization for second dose of GARDASIL the multipurpose health worker was informed that the patient developed fever on 01-AUG-2009 and was treated by local registered medical practitioner (RMP). The patient did not recover and was admitted to the hospital on 08-AUG-2009. On the same day, GENTAMYCIN was given. She developed dyspnoea and went into coma and so was referred and was shifted to another hospital where she expired on 08-AUG-2009 at around 9:00 pm. The cause of death was determined as "death due to viral fever". The information was provided from patient''s maternal grandparents as she was staying with them. This event occurred after 23 days of receiving first dose of GARDASIL. The female health worker informed the medical officer in charge and he investigated the death and completed the first information report as per AEFI guidelines. The case sheet mentions as "pyrexia of unknown origin". This information was then communicated to district immunization officer, who determined that the death was not related to the vaccine and so a decision was taken to close the investigation.


VAERS ID: 382971 (history)  
Form: Version 1.0  
Age: 10.0  
Sex: Female  
Location: Foreign  
Vaccinated:2009-10-09
Onset:2009-10-29
   Days after vaccination:20
Submitted: 2010-03-18
   Days after onset:140
Entered: 2010-03-18
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV2: HPV (CERVARIX) / GLAXOSMITHKLINE BIOLOGICALS AHPVA050AG / 2 LA / IM

Administered by: Other       Purchased by: Other
Symptoms: Basophil percentage decreased, Blood smear test abnormal, Death, Eosinophil percentage, Haemoglobin decreased, Headache, Lymphocyte percentage, Malaria, Monocyte percentage decreased, Neutrophil percentage increased, Pyrexia, White blood cell count increased
SMQs:, Haematopoietic erythropenia (broad), Haematopoietic leukopenia (broad), Haemorrhage laboratory terms (broad), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Opportunistic infections (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2009-10-30
   Days after onset: 1
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness: Unknown
Preexisting Conditions:
Allergies:
Diagnostic Lab Data: Basophils, 30Oct2009, 0%; Blood smear test, 30Oct2009, Positive; Eosinophils, 30Oct2009, 1%; Hemoglobin, 30Oct2009, 4g/dl; Lymphocytes, 30Oct2009, 28%; Monocytes, 30Oct2009, 0%; Neutrophils, 30Oct2009, 71%; White blood cell count, 30Oct2009, 46200/mm3
CDC Split Type: B0639818A

Write-up: This case was reported by a healthcare professional and described the occurrence of malaria in a 10-year-old female subject who was vaccinated with CERVARIX (GlaxoSmithKline). Previous and/or concurrent vaccination included CERVARIX; GlaxoSmithKline; intramuscular; left deltoid given on 2 September 2009. On 9 October 2009, the subject received 2nd dose of CERVARIX (intramuscular, left deltoid). No adverse event was reported during the observation period of 30 minutes after each dose of CERVARIX. The subject migrated to another village with her parents. She was in good condition and doing well. On 29 October 2009, 1 month after vaccination with the 2nd dose of CERVARIX, the subject experienced severe headache and fever. She visited a private local clinic for treatment as an outdoor patient. The subject was given an injection of an unspecified drug in the right upper arm by the physician. Malaria was suspected and a blood test was prescribed. Unspecified medication was also provided by the physician. On 30 October 2009, the subject was brought to the hospital in critical condition. The laboratory test on blood showed low hemoglobin level 4g/dl which is only 27.58% of a normal level, white blood cells 46200/mm3 with 71% neutrophils, 28% lymphocytes, 1% eosinophils, 0% monocytes and 0% basophils. The thin and thick blood smear analysis revealed many rings of trophozoites and schizont of plasmodium Vivax. The diagnosis of malaria was made. The subject was sent to the community health center where a treatment was started. Around 1 hour later, the subject was declared dead. The subject died on 30 October 2009 from malaria. An autopsy was not performed.


VAERS ID: 384205 (history)  
Form: Version 1.0  
Age: 13.0  
Sex: Female  
Location: Foreign  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2010-04-02
Entered: 2010-04-05
   Days after submission:3
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 1 UN / UN

Administered by: Other       Purchased by: Other
Symptoms: Death, Headache, Vaccine positive rechallenge
SMQs:

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: Unknown
CDC Split Type: WAES1003USA04772

Write-up: Information has been received from a nurse practitioner concerning a 13 year old female patient who on unspecified dates was vaccinated with three doses of GARDASIL at the nurse practitioner''s previous practice. The patient experienced headache after getting first and second dose of GARDASIL. The patient sought unspecified medical attention. After the third dose of GARDASIL the patient experienced headache and died on the same day. The cause of death was not reported. Additional information has been requested.


VAERS ID: 387594 (history)  
Form: Version 1.0  
Age: 11.0  
Sex: Female  
Location: Foreign  
Vaccinated:2010-01-22
Onset:2010-04-28
   Days after vaccination:96
Submitted: 2010-05-14
   Days after onset:16
Entered: 2010-05-17
   Days after submission:3
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 3 UN / UN

Administered by: Unknown       Purchased by: Unknown
Symptoms: Death
SMQs:

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2010-04-29
   Days after onset: 1
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: Unknown
CDC Split Type: WAES1005USA01063

Write-up: Information has been received from a physician via the Program for Appropriate Technology concerning an 11 year old patient who on 21-JUL-2009 and 09-OCT-2009 was vaccinated with a first and second dose of GARDASIL respectively (routes, site of injection and lot numbers not reported). On 22-JAN-2010, the patient received her third dose of GARDASIL respectively (route, site of injection and lot number not reported). Subsequently, the patient died on 29-APR-2010, 96 days after the patient received her third dose. Additional information has been expected.


VAERS ID: 389806 (history)  
Form: Version 1.0  
Age:   
Sex: Female  
Location: Foreign  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2010-06-01
Entered: 2010-06-02
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 3 UN / UN

Administered by: Unknown       Purchased by: Unknown
Symptoms: Completed suicide, Death
SMQs:, Suicide/self-injury (narrow)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: Unknown
CDC Split Type: WAES1005USA04360

Write-up: Information has been received from a health professional, via the Program for Appropriate Technology (PATH), concerning a female patient who on an unspecified date, was vaccinated with the third dose of GARDASIL. Subsequently, on an unspecified date, the patient committed suicide. The cause of death was suicide. At this time, relationship of suicide death to GARDASIL is unknown. Additional information has been requested.


VAERS ID: 391339 (history)  
Form: Version 1.0  
Age: 16.0  
Sex: Female  
Location: Foreign  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2010-06-23
Entered: 2010-06-24
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / UNK UN / UN

Administered by: Unknown       Purchased by: Unknown
Symptoms: Death, Ovarian cancer
SMQs:, Ovarian malignant tumours (narrow), Non-haematological malignant tumours (narrow)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: Unknown
CDC Split Type: WAES1006USA03011

Write-up: Information has been received from a physician via CSL as part of a business agreement (manufacturer control # 20100617KC1) concerning a 16 year old female who on an unspecified date was vaccinated with a dose of GARDASIL (lot # not reported). After the GARDASIL vaccination, 3 months later, the patient died of ovarian cancer. The patient was treated at a women''s hospital. The physician stated that there was no causal relationship between the vaccine and death. Additional information has been requested.


VAERS ID: 393523 (history)  
Form: Version 1.0  
Age: 12.0  
Sex: Female  
Location: Foreign  
Vaccinated:2008-11-07
Onset:2008-11-28
   Days after vaccination:21
Submitted: 2010-07-23
   Days after onset:601
Entered: 2010-07-23
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV2: HPV (CERVARIX) / GLAXOSMITHKLINE BIOLOGICALS AHPVA021AA / 1 UN / IM

Administered by: Other       Purchased by: Other
Symptoms: Ascites, Autopsy, Bronchopneumonia, Cardiac arrest, Cough, Death, Dyspnoea, Endotracheal intubation, Generalised oedema, Hypotension, Inflammation, Lower respiratory tract infection, Mechanical ventilation, Mediastinitis, Necrosis, Oedema, Pleural effusion, Pleurisy, Pyrexia, Respiratory distress, Respiratory syncytial virus infection, Respiratory syncytial virus test positive, Skin oedema, Speech disorder, Streptococcal sepsis, Streptococcus test positive, Tachycardia, Tachypnoea, Tracheitis, Upper respiratory tract infection, Upper respiratory tract inflammation
SMQs:, Torsade de pointes/QT prolongation (broad), Cardiac failure (broad), Liver related investigations, signs and symptoms (narrow), Hepatic failure, fibrosis and cirrhosis and other liver damage-related conditions (narrow), Anaphylactic reaction (narrow), Acute pancreatitis (broad), Angioedema (broad), Asthma/bronchospasm (broad), Neuroleptic malignant syndrome (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Arrhythmia related investigations, signs and symptoms (broad), Shock-associated circulatory or cardiac conditions (excl torsade de pointes) (narrow), Dementia (broad), Acute central respiratory depression (broad), Psychosis and psychotic disorders (broad), Pulmonary hypertension (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Haemodynamic oedema, effusions and fluid overload (narrow), Cardiomyopathy (broad), Eosinophilic pneumonia (broad), Hypersensitivity (broad), Respiratory failure (narrow), Drug reaction with eosinophilia and systemic symptoms syndrome (broad), Infective pneumonia (narrow), Dehydration (broad), Hypokalaemia (broad), Sepsis (narrow), Opportunistic infections (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2008-11-28
   Days after onset: 0
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness: Unknown
Preexisting Conditions:
Allergies:
Diagnostic Lab Data: Body height, 02Dec2008, 172cm; Respiratory rate, 28Nov2008, 60 (at admission); Weight, 02Dec2008, 59kg; 02 Dec 2008: Bacterial test B haemolytic strep group B. 02 Dec 2008: Viral test. Nasal swab: respiratory syncytical virus.
CDC Split Type: B0554054A

Write-up: This case was reported by the Medicines and Healthcare products Regulatory Agency (GB-MHRA-ADR 20357549) and described the occurrence of streptococcal septicemia in a 12-year-old female subject who was vaccinated with CERVARIX. Previous vaccinations included 1st dose CERVARIX given 07 October 2008, smallpox vaccine 1996 and November 2000, Meningococcal c vaccine 22 November 2000, MMR vaccine 22 November 2000, Diphtheria toxoid 1996 and November 2000, Hib vaccine 1996 and November 2000, bacillus clostridium tetani 1996 and November 2000, whooping cough vaccine 1996 and November 2000 and poliomyelitis vaccine 1996 and November 2000. On 7 November 2008 the subject received unspecified second dose of CERVARIX (.5 ml, intramuscular, batch AHPVA021AA). At an unspecified time after vaccination with CERVARIX, the subject experienced streptococcal septicemia. The subject died on 30 November 2008 from streptococcal septicemia. It was unknown whether an autopsy was performed. MHRA Verbatim Text: Patient died 3 weeks following 2nd HPV Vaccination. Reported to have died due to Streptococcal A Septicemia. Still awaiting coroners verdict. Follow-up information received on 14 July 2010 from the MHRA: The patient had a cough for one week and then developed fever for three days. Patient was admitted to hospital three weeks after CERVARIX vaccination when the cough got worse and they developed difficulty breathing. On admission the respiratory rate was 60 per minute and they were distressed. They became so distressed they were unable to speak. The patient was transferred to the high dependency unit. On 28 November 2008 the patient then became tachycardic and a chest infection was diagnosed and the patient was taken to the theatre and intubated and ventilated. The patient crashed an hour later and had arrests characterized by very severe hypotension. The patient became asystolic. Despite all efforts the decision that further attempts were futile was made and the patient died on 28 November 2008. The cause of death was streptococcal septicemia. The coroner states that there is no doubt death was due to a group A streptococcal septicaemia. There was active inflammation of the upper respiratory tracts, the mediastinum, and focally the lungs. Group A streptococcus was cultured from multiple sites both at post-mortem and during the short terminal illness. It was noted that a respiratory syncytial virus was identified from the nose swab. According to the coroner it was probable that an upper respiratory tract infection was the portal of the devastating bacterial infection that caused death and it was possible that the respiratory syncytial virus was significant here. Post mortem results: A post mortem was carried out and there was found to be a considerable degree of generalized subcutaneous oedema. Both pleural cavities contained approximately 150mls of turbid yellow fluid. The lungs were found to have a necrotizing pleuritis with some extension of acute inflammation into the pulmonary parenchyma that is immediately adjacent to the pleural surface, though extensive pneumonia is not identified. Some inflammation and oedema extends into the pulmonary interstitium in the areas close to the pleural and mediastinal surface of the lungs. Some areas of bronchopneumonia are identified. The pericardial cavity contains approximately 50ml of clear liquid and the peritoneal cavity contains approximately 250-300ml of clear yellow fluid. The trachea shows evidence of an acute tracheitis with mediastinitis of the upper mediastinum. The larynx shows evidence of an upper respiratory tract infection. The thymus shows marked oedema, and the presence of scattered inflammatory cells.


VAERS ID: 393871 (history)  
Form: Version 1.0  
Age: 15.0  
Sex: Female  
Location: Foreign  
Vaccinated:2010-05-25
Onset:2010-05-28
   Days after vaccination:3
Submitted: 2010-07-28
   Days after onset:61
Entered: 2010-07-29
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. NJ29430 / 2 UN / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Completed suicide, Death
SMQs:, Suicide/self-injury (narrow)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2010-05-28
   Days after onset: 0
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness:
Preexisting Conditions: Depression
Allergies:
Diagnostic Lab Data: Unknown
CDC Split Type: WAES1007USA03148

Write-up: Information has been received from the agency via a Case Line Listing via CSL, as part of a business agreement, concerning a 15 year old female patient with a history of depression who on 25-MAY-2010, was vaccinated with the second 0.5 ml IM dose of GARDASIL (batch # NK20450, lot # NJ29430). On 28-MAY-2010, within one week following vaccination, the patient experienced suicide (severe) and died. The cause of death was suicide. The agency felt that suicide was unlikely related to therapy with GARDASIL. No further information is available. A lot check has been initiated. This was originally reported by a practice nurse.


VAERS ID: 396027 (history)  
Form: Version 1.0  
Age: 14.0  
Sex: Female  
Location: Foreign  
Vaccinated:0000-00-00
Onset:0000-00-00
Submitted: 2010-08-19
Entered: 2010-08-20
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 2 UN / UN

Administered by: Unknown       Purchased by: Unknown
Symptoms: Sudden death
SMQs:, Torsade de pointes/QT prolongation (broad), Arrhythmia related investigations, signs and symptoms (broad), Cardiomyopathy (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Unknown
Current Illness:
Preexisting Conditions: Unknown
Allergies:
Diagnostic Lab Data: Unknown
CDC Split Type: WAES1008USA01799

Write-up: Information has been received from a consumer, as part of a marketing research program concerning a 14 year old female who on an unspecified date was vaccinated with the second dose of GARDASIL (Lot # unknown). The consumer reported that the patient who was a friend of her daughter died suddenly 2 weeks after receiving the second dose of GARDASIL. No further information is available.


VAERS ID: 398755 (history)  
Form: Version 1.0  
Age: 0.2  
Sex: Female  
Location: Foreign  
Vaccinated:2010-09-01
Onset:2010-09-01
   Days after vaccination:0
Submitted: 2010-09-16
   Days after onset:15
Entered: 2010-09-17
   Days after submission:1
Vaccin­ation / Manu­facturer Lot / Dose Site / Route
HPV4: HPV (GARDASIL) / MERCK & CO. INC. - / 1 UN / IM

Administered by: Unknown       Purchased by: Unknown
Symptoms: Death, Drug exposure via breast milk, General physical health deterioration
SMQs:, Neonatal exposures via breast milk (narrow)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: None
Current Illness:
Preexisting Conditions: None
Allergies:
Diagnostic Lab Data: None
CDC Split Type: WAES1009USA00625B1

Write-up: Information has been received from a physician for the pregnancy registry for GARDASIL, concerning a female who on 01-SEP-2010 was vaccinated with the first dose of GARDASIL (lot number not reported) intramuscularly while breastfed her baby was 40 day old (WAES 1009USA00625), it was reported that the mother''s and baby''s health were good (well controlled). On 02-SEP-2010, in the morning, the baby''s condition was still good but in the afternoon the condition suddenly drop. The family immediately took the baby to hospital and it did not help since the baby died shortly after that. The cause of death was not reported, it was also reported as "not recovered from death". No further information is available.


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